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The proteomic landscape of genome-wide genetic perturbations. Cell 43.
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BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage. Development, dev.201450 (2023)
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Creation of a structured molecular genomics report for Germany as a local adaption of HL7's Genomic Reporting Implementation Guide. Journal of the American Medical Informatics Association, ocad061 (2023)
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Quantitative protein biomarker panels: a path to improved clinical practice through proteomics. Embo Molecular Medicine 46.
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Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation. Nature Communications 47.
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Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex. Nature Communications 48.
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Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors. npj Regenerative Medicine 49.
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Endosome dysfunction leads to gain-of-function TLR7 and human lupus. bioRxiv (Preprint Server) (2023)
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Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 51.
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Prediction of protein–protein interactions using sequences ofintrinsically disordered regions. Proteins: Structure, Function, and Bioinformatics 52.
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Comparison of Empirical Zn2+ Models in Protein–DNA Complexes. biophysica 53.
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Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3. Nature Communications 54.
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FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature 55.
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8, pp. 441 - 454 (2023)
Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC. Nature Microbiology 56.
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Linear: a framework to enable existing software to resolve structural variants in long reads with flexible and efficient alignment-free statistical models. Briefings in Bioinformatics 57.
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Cryo-EM captures early ribosome assembly in action. Nature Communications 58.
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Aberrant phase separation and nucleolar dysfunction in rare genetic diseases. Nature 59.
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Flow-Matching: Efficient Coarse-Graining of Molecular Dynamics. Journal of Chemical Theory and Computation 60.
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19 (2), e1009894 (2023)
AI reveals insights into link between CD33 and cognitive impairment in Alzheimer’s Disease. PLOS Computational Biology