Contact

Aydan Bulut-Karslioglu, PhD
Aydan Bulut-Karslioglu, PhD
Head of Research Group
Phone:+1 510 4957447
Email:aydan@...

Institute of Regeneration Medicine, University of California San Francisco, CA, USA

Aydan Bulut-Karslioglu will move to the Max Planck Institute for Molecular Genetics in summer 2018.

Bulut-Karslioglu lab

Bulut-Karslioglu lab /Stem Cell Chromatin Group

A diapaused mouse embryo. Pluripotent cells are shown in red. Zoom Image
A diapaused mouse embryo. Pluripotent cells are shown in red. [less]

Our lab studies the molecular mechanisms of chromatin and gene regulation in stem cells and in the developing embryo. Specifically, we aim to dissect the crosstalk between metabolism and chromatin in pluripotent stem cells. Our research strategy integrates in vivo and in vitro techniques, biochemistry, imaging, molecular and developmental biology to study the above questions. Metabolo-epigenetic regulation is widely relevant to numerous cell types across organisms, particularly to stem/progenitor populations at the forefront of quiescence vs proliferation decisions in embryonic and adult tissues and disease states. By employing other stem cell models such as neural stem/progenitor cells, we aim to uncover regulatory pathways critical for the timing of proliferation across mammalian stem cells.

 
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