Herwig lab / Bioinformatics Group

Research concept

Research covers i) the development of computational methods for the analysis of molecular data often in collaborative research projects and ii) the integration and interpretation of these data in the context of biological networks. The group has developed computational methods for RNA-seq and MeDIP-seq and works on the integrative analysis of these data in order to elucidate the interplay of methylation, gene expression and genome structure that are operative in human (disease) processes related to cancer, diabetes and drug toxicity. Furthermore, the group has developed and maintains the ConsensusPathDB molecular interaction resource which is a widely used research resource (~970 paper citations).

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