Publication Overview

Journal Article (2265)

1. 1.
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   Lehrach, H.: Virtual Clinical Trials, an Essential Step in Increasing the Effectiveness of the Drug Development Process. Public Health Genomics (2051)
2. 2.
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   Auburger, G.; Sen, N.-E.; Meierhofer, D.; Başak, A.-N.; Gitler, A. D.: Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2. Trends in Neurosciences 40 (8), pp. 507 - 516 (2017)
3. 3.
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   Binder, H.; Hopp, L.; Schweiger, M. R.; Hoffmann, S.; Jühling, F.; Kerick, M.; Timmermann, B.; Siebert, S.; Grimm, C.; Nersisyan, L. et al.; Arakelyan, A.; Herberg, M.; Buske, P.; Loeffler-Wirth, H.; Rosolowski, M.; Engel, C.; Przybilla, J.; Peifer, M.; Friedrichs, N.; Moeslein, G.; Odenthal, M.; Hussong, M.; Peters, S.; Holzapfel, S.; Nattermann, J.; Hueneburg, R.; Schmiegel, W.; Royer-Pokora, B.; Aretz, S.; Kloth, M.; Kloor, M.; Buettner, R.; Galle, J.; Loeffler, M.: Genomic and transcriptomic heterogeneity of colorectal tumors arising in Lynch Syndrome. The Journal of Pathology (2017)
4. 4.
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   Choi, J.; Clement, K.; Huebner, A. J.; Webster, J.; Etchegaray, J.-P.; Gu, H.; Boyle, P.; Elling, U.; Mostoslavsky, R.; Sadreyev, R. et al.; Park, P. J.; Gygi, S. P.; Meissner, A.; Hochedlinger, K.: DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell 20 (5), pp. 706 - 719 (2017)
5. 5.
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   Choi, J.; Huebner, A. J.; Clement, K.; Walsh, R. M.; Savol, A.; Lin, K.; Gu, H.; Di Stefano, B.; Brumbaugh, J.; Kim, S.-Y. et al.; Sharif, J.; Rose, C. M.; Mohammad, A.; Odajima, J.; Charron, J.; Shioda, T.; Gnirke, A.; Gygi, S.; Koseki, H.; Sadreyev, R. I.; Xiao, A.; Meissner, A.; Hochedlinger, K.: Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature 548 (7666), pp. 219 - 223 (2017)
6. 6.
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   Corwin, T.; Woodsmith, J.; Apelt, F.; Fontaine, J.-F.; Meierhofer, D.; Helmuth, J.; Grossmann, A.; Andrade-Navarro, M. A.; Ballif, B. A.; Stelzl, U.: Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate. Cell Systems (2017)
7. 7.
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   Koch, F.; Scholze, M.; Wittler, L.; Schifferl, D.; Sudheer, S.; Grote, P.; Timmermann, B.; Macura, K.; Herrmann, B. G.: Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors. Developmental Cell 42, pp. 1 - 13 (2017)
8. 8.
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   Lange, L.; Marks, M.; Liu, J.; Wittler, L.; Bauer, H.; Piehl, S.; Bläß, G.; Timmermann, B.; Herrmann, B. G.: Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a. Biology Open 6 (6), pp. 752 - 764 (2017)
9. 9.
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   Lienhard, M.; Grasse, S.; Rolff, J.; Frese, S.; Schirmer, U.; Becker, M.; Börno, S. T.; Timmermann, B.; Chavez, L.; Sültmann, H. et al.; Leschber, G.; Fichtner, I.; Schweiger, M. R.; Herwig, R.: QSEA – modelling of genome-wide DNA methylation from sequencing enrichment experiments. Nucleic Acids Research (London) (2017)
10. 10.
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    Lim, S.-Y.; Macheleidt, I.; Dalvi, P.; Schäfer, S. C.; Kerick, M.; Ozretić, L.; Ortiz-Cuaran, S.; George, J.; Merkelbach-Bruse, S.; Wolf, J. et al.; Timmermann, B.; Thomas, R. K.; Schweiger, M. R.; Buettner, R.; Odenthal, M.: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells. Scientific Reports (2017)
11. 11.
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    Lorenz, C.; Lesimple, P.; Bukowiecki, R.; Zink, A.; Inak, G.; Mlody, B.; Singh, M.; Semtner, M.; Mah, N.; Auré, K. et al.; Leong, M.; Zabiegalov, O.; Lyras, E.-M.; Pfiffer, V.; Fauler, B.; Eichhorst, J.; Wiesner, B.; Huebner, N.; Priller, J.; Mielke, T.; Meierhofer, D.; Izsvák, Z.; Meier, J. C.; Bouillaud, F.; Adjaye, J.; Schuelke, M.; Wanker, E. E.; Lombès, A.; Prigione, A.: Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell 20 (5), e9, pp. 659 - 674 (2017)
12. 12.
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    Love, M. I.; Huska, M.; Jurk, M.; Schöpflin, R.; Starick, S. R.; Schwahn, K.; Cooper, S. B.; Yamamoto, K. R.; Thomas-Chollier, M.; Vingron, M. et al.; Meijsing, S. H.: Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation. Nucleic Acids Research (London) 45 (4), pp. 1805 - 1819 (2017)
13. 13.
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    Medina, A. B.; Banaszczak, M.; Ni, Y.; Aretz, I.; Meierhofer, D.: ρ⁰ Cells Feature De-Ubiquitination of SLC Transporters and Increased Levels and Fluxes of Amino Acids. International Journal of Molecular Sciences (2017)
14. 14.
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    Seidel, G.; Meierhofer, D.; Şen, N.-E.; Guenther, A.; Krobitsch, S.; Auburger, G.: Quantitative Global Proteomics of Yeast PBP1 Deletion Mutants and Their Stress Responses Identifies Glucose Metabolism, Mitochondrial, and Stress Granule Changes. Journal of Proteome Research 16 (2), pp. 504 - 515 (2017)
15. 15.
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    Torres-Odio, S.; Key, J.; Hoepken, H.-H.; Canet-Pons, J.; Valek, L.; Roller, B.; Walter, M.; Morales-Gordo, B.; Meierhofer, D.; Harter, P. N. et al.; Mittelbronn, M.; Tegeder, I.; Gispert, S.; Auburger, G.: Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. Journal of Neuroinflammation (2017)
16. 16.
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    Twardziok, M.; Meierhofer, D.; Börno, S. T.; Timmermann, B.; Jäger, S.; Boral, S.; Eggert, A.; Delebinski, C. I.; Seifeert, G.: Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses. BMC Complementary and Alternative Medicine (2017)
17. 17.
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    Warren, C. R.; O’Sullivan, J. F.; Friesen, M.; Becker, C. E.; Zhang, X.; Liu, P.; Wakabayashi, Y.; Morningstar, J. E.; Shi, X.; Choi, J. et al.; Xia, F.; Peters, D. T.; Florido, M. H. C.; Tsankov, A. M.; Duberow, E.; Comisar, L.; Shay, J.; Jiang, X.; Meissner, A.; Musunuro, K.; Kathiresan, S.; Daheron, L.; Zhu, J.; Gerszten, R. E.; Deo, R. C.; Vasan, R. S.; O’Donnell, C. J.; Cowan, C. A.: Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell 20 (4), pp. 547 - 557 (2017)
18. 18.
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    Xu, S.; Brockmoeller, T.; Navarro-Quezada, A.; Kuhl, H.; Gase, K.; Ling, Z.; Zhou, W.; Kreitzer, C.; Stanke, M.; Tang, H. et al.; Lyons, E.; Pandey, P.; Pandey, S. P.; Timmermann, B.; Gaquerel, E.; Baldwin, I. T.: Wild tobacco genomes reveal the evolution of nicotine biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 114 (23), pp. 6133 - 6138 (2017)
19. 19.
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    Yang, J.; Moeinzadeh, M. H.; Kuhl, H.; Helmuth, J.; Xiao, P.; Haas, S.; Liu, G.; Zheng, J.; Sun, Z.; Fan, W. et al.; Deng, G.; Wang, H.; Hu, F.; Zhao, S.; Fernie, A. R.; Börno, S. T.; Timmermann, B.; Zhang, P.; Vingron, M.: Haplotype-resolved sweet potato genome traces back its hexaploidization history. Nature Plants (2017)
20. 20.
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    Yu , V. W. C.; Yusuf , R. Z.; Oki , T.; Wu, J.; Saez, B.; Wang, X.; Cook , C.; Baryawno , N.; Ziller , M. J.; Lee , E. et al.; Gu, H.; Meissner, A.; Lin, C. P.; Kharchenko, P. V.; Scadden , D. T.: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells - Correction. Cell 168 (5), pp. 944 - 945 (2017)