Publication Overview

Journal Article (2561)

1. 1.
   MPG.PuRe

   DOI
   Journal Article

   Grimm, C.; Fischer, A.; Farrelly, A. M.; Kalachand, R.; Castiglione, R.; Wasserburger, E.; Hussong, M.; Schultheis, A. M.; Altmüller, J.; Thiele, H. et al.; Reinhardt, H. C.; Hauschulz, K.; Hennessy, B. T.; Herwig, R.; Lienhard, M.; Buettner, R.; Schweiger, M. R.: Combined Targeted Re-Sequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for PARP1 Inhibitor Sensitivity Testing. The Journal of Molecular Diagnostics 21 (2), pp. 198 - 213 (2019)
2. 2.
   MPG.PuRe

   DOI

   publisher-version
   Journal Article

   Kraft, K.; Magg, A.; Heinrich, V.; Riemenschneider, C.; Schöpflin, R.; Markowski, J.; Ibrahim, D.; Acuna-Hidalgo, R.; Despang, A.; Andrey, G. et al.; Wittler, L.; Timmermann, B.; Vingron, M.; Mundlos, S.: Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 21 (3), pp. 305 - 310 (2019)
3. 3.
   MPG.PuRe

   DOI

   PDF
   Journal Article

   Kahrizi, K.; Hu, H.; Hosseini, M.; Kalscheuer, V. M.; Fattahi, Z.; Beheshtian, M.; Suckow, V.; Mohseni, M.; Lipkowitz, B.; Mehvari, S. et al.; Mehrjoo, Z.; Akhtarkhavari, T.; Ghaderi, Z.; Rahimi, M.; Arzhangi, S.; Jamali, P.; Falahat Chian, M.; Nikuei , P.; Sabbagh Kermani, F.; Sadeghinia, F.; Jazayeri , R.; Tonekaboni, S. H.; Khoshaeen, A.; Habibi, H.; Pourfatemi, F.; Mojahedi , F.; Khodaie‐Ardakani, M.; Najafipour, R.; Wienker, T. F.; Najmabadi , H.; Ropers, H.-H.: Effect of inbreeding on intellectual disability revisited by Trio sequencing. Clinical Genetics: an international journal of genetics in medicine 95 (1), pp. 151 - 159 (2019)
4. 4.
   MPG.PuRe

   DOI

   PDF
   Journal Article

   Gerhauser, C.; Favero, F.; Risch, T.; Simon, R.; Feuerbach, L.; Assenov, Y.; Heckmann, D.; Sidiropoulos, N.; Waszak, S. M.; Hübschmann, D. et al.; Urbanucci, A.; Girma, E. G.; Kuryshev, V.; Klimczak, L. J.; Saini, N.; Stütz, A. M.; Weichenhan, D.; Böttcher, L.-M.; Toth, R.; Hendriksen, J. D.; Koop, C.; Lutsik, P.; Matzk, S.; Warnatz, H.-J.; Amstislavskiy, V.; Feuerstein, C.; Raeder, B.; Bogatyrova, O.; Schmitz, E.-M.; Hube-Magg, C.; Kluth, M.; Huland, H.; Graefen, M.; Lawerenz, C.; Henry, G. H.; Yamaguchi, T. N.; Malewska, A.; Meiners, J.; Schilling, D.; Reisinger, E.; Eils, R.; Schlesner, M.; Strand, D. W.; Bristow, R. G.; Boutros, P. C.; von Kalle, C.; Gordenin, D.; Sültmann, H.; Brors, B.; Sauter, G.; Plass, C.; Yaspo, M.-L.; Korbel, J. O.; Schlomm, T.; Weischenfeldt, J.: Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories. Cancer Cell 34 (6), pp. 996 - 1011 (2018)
5. 5.
   MPG.PuRe

   DOI

   PDF
   Journal Article

   Adachi, K.; Kopp, W.; Wu, G.; Heising, S.; Greber, B.; Stehling, M.; Araúzo-Bravo, M. J.; Boerno, S. T.; Timmermann, B.; Vingron, M. et al.; Schöler, H. R.: Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency - Correction. Cell Stem Cell 23 (6), pp. 900 - 904 (2018)
6. 6.
   MPG.PuRe

   DOI
   Journal Article

   Hudert , C. A.; Selinski, S.; Rudolph, B.; Bläker, H.; Loddenkemper, C.; Thielhorn, R.; Berndt, N.; Golka, K.; Cadenas, C.; Reinders, J. et al.; Henning, S.; Bufler, P.; Jansen, P. L. M.; Holzhütter, H. G.; Meierhofer, D.; Hengstler, J. G.; Wiegand, S.: Genetic determinants of steatosis and fibrosis progression in pediatric non-alcoholic fatty liver disease. Liver International 2018 (2018)
7. 7.
   MPG.PuRe

   DOI
   Journal Article

   Hudert, C. A.; Selinski, S.; Rudolph, B.; Bläker, H.; Loddenkemper, C.; Thielhorn, R.; Berndt, N.; Golka, K.; Cadenas, C.; Reinders, J. et al.; Henning, S.; Bufler, P.; Jansen, P. L. M.; Holzhütter, H.; Meierhofer, D.; Hengstler, J. G.; Wiegand, S.: Genetic determinants of steatosis and fibrosis progression in paediatric non‐alcoholic fatty liver disease. Liver International 2018, pp. 1 - 17 (2018)
8. 8.
   MPG.PuRe

   DOI

   PDF
   Journal Article

   Schöne, S.; Bothe, A. M.; Einfeldt, E.; Borschiwer, M.; Benner, P. F.; Vingron, M.; Thomas-Chollier, M.; Meijsing, S. H.: Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise. PLoS Genetics 14 (11), e1007793 (2018)
9. 9.
   MPG.PuRe

   DOI

   PDF
   Journal Article

   Barel, G.; Herwig, R.: Network and Pathway Analysis of Toxicogenomics Data. Frontiers in Genetics 9, 9:484 (2018)
10. 10.
    MPG.PuRe

    DOI
    Journal Article

    Khayat, W.; Hackett , A.; Shaw, M.; Ilie , A.; Dudding-Byth , T.; Kalscheuer, V. M.; Christie , L.; Corbett , M. A.; Juusola , J.; Friend, K. L. et al.; Kirmse , B. M.; Gecz , J.; Field, M.; Orlowski, J.: A recurrent missense variant in SLC9A7 causes nonsyndromic X-linked intellectual disability with alteration of Golgi acidification and aberrant glycosylation. Human Molecular Genetics (2018)
11. 11.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Basilicata, M. F.; Bruel, A.-L.; Semplicio, G.; Keller Valsecchi, C. I.; Aktaş, T.; Duffourd, Y.; Rumpf, T.; Morton, J.; Bache, I.; Szymanski, W. G. et al.; Gilissen, C.; Vanakker, O.; Õunap, K.; Mittler, G.; van der Burgt, I.; El Chehadeh, S.; Cho, M. T.; Pfundt, R.; Tan, T. Y.; Kirchhoff, M.; Menten, B.; Vergult, S.; Lindstrom, K.; Reis, A.; Johnson, D. S.; Fryer, A.; McKay, V.; Study, D. D. D.; Fisher, R. B.; Thauvin-Robinet, C.; Francis, D.; Roscioli, T.; Pajusalu, S.; Radtke, K.; Ganesh, J.; Brunner, H. G.; Wilson, M.; Faivre, L.; Kalscheuer, V. M.; Thevenon, J.; Akhtar, A.: De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nature Genetics 50 (10), pp. 1442 - 1451 (2018)
12. 12.
    MPG.PuRe

    DOI

    PDF

    PDF
    Journal Article

    Kragesteen , B. K.; Spielmann, M.; Paliou, C.; Heinrich, V.; Schöpflin, R.; Esposito, A.; Annunziatella, C.; Bianco , S.; Chiariello, A. M.; Jerković , I. et al.; Harabula, I.; Guckelberger, P.; Pechstein, M.; Wittler, L.; Chan, W.-L.; Franke, M.; Lupiáñez , D. G.; Kraft, K.; Timmermann, B.; Vingron, M.; Visel, A.; Nicodemi, M.; Mundlos, S.; Andrey, G.: Dynamic 3D chromatin architecture determines enhancer specificity and morphogenetic identity in limb development. Nature Genetics 50 (10), pp. 1463 - 1473 (2018)
13. 13.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Verheijen, M. C. T.; Schrooders, Y.; Nudischer, R.; Börno, S. T.; Schlapbach, R.; Gotta, S.; Kleinjans, J. C. S.; Lienhard, M.; Clayton, O.; Timmermann, B. et al.; Selevsek, N.; Gmuender, H.; Herwig, R.; Caiment, F.: DMSO-induced drastic changes in cellular processes and epigenetic landscape in vitro. TOXICOLOGY LETTERS 2018, 295:S215 (2018)
14. 14.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Adachi, K.; Kopp, W.; Wu, G.; Heising, S.; Greber, B.; Stehling, M.; Araúzo-Bravo, M. J.; Boerno, S. T.; Timmermann, B.; Vingron, M. et al.; Schöler, H. R.: Esrrb unlocks silenced enhancers for reprogramming to naïve pluripotency. Cell Stem Cell 23 (2), pp. 266 - 275 (2018)
15. 15.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Adachi, K.; Kopp, W.; Wu, G.; Heising, S.; Greber, B.; Stehling , M.; Araúzo-Bravo, M. J.; Boerno, S. T.; Timmermann, B.; Vingron, M. et al.; Schöler, H. R.: Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency. Cell Stem Cell 23 (2), pp. 266 - 275 (2018)
16. 16.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Grasse, S.; Lienhard, M.; Frese, S.; Kerick, M.; Steinbach, A.; Grimm, C.; Hussong, M.; Rolff, J.; Becker, M.; Dreher, F. et al.; Schirmer, U.; Boerno, S. T.; Ramisch, A.; Leschber, G.; Timmermann, B.; Grohé, C.; Lüders, H.; Vingron, M.; Fichtner, I.; Klein, S.; Odenthal, M.; Büttner, R.; Lehrach, H.; Sültmann, H.; Herwig, R.; Schweiger, R. M.: Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance. Genome Medicine 10 (1), 10:55 (2018)
17. 17.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Charzewska, A.; Maiwald, R.; Kahrizi, K.; Oehl‐Jaschkowitz, B.; Dufke, A.; Lemke, J. R.; Enders, H.; Najmabadi, H.; Tzschach, A.; Hachmann, W. et al.; Jensen, C.; Bienek, M.; Poznański, J.; Nawara, M.; Chilarska, T.; Obersztyn, E.; Hoffman‐Zacharska, D.; Gos, M.; Bal, J.; Kalscheuer, V. M.: The power of the Mediator complex—Expanding the genetic architecture and phenotypic spectrum of MED12‐related disorders. Clinical Genetics: an international journal of genetics in medicine 2018, 13412 (2018)
18. 18.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Selvan, N.; George, S.; Serajee, F. J.; Shaw, M.; Hobson, L.; Kalscheuer, V.; Nripesh, P.; Levy, S. E.; Taylor, J.; Aftimos, S. et al.; Schwartz, C. E.; Huq, A. M.; Gecz, J.; Wells, L.: O-GlcNAc transferase missense mutations linked to X-linked intellectual disability deregulate genes involved in cell fate determination and signaling. Journal of Biological Chemistry 293 (27), pp. 10810 - 10824 (2018)
19. 19.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Berndt, N.; Bulik, S.; Wallach, I.; Wünsch, T.; König, M.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology. Nature Communications 9 , 9:2386 (2018)
20. 20.
    MPG.PuRe

    DOI

    PDF
    Journal Article

    Louloupi, A.; Ntini, E.; Conrad, T.; Ørom, U. A.: Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency. Cell Reports 23 (12), pp. 3429 - 3437 (2018)