Publication Overview

De Maio, N.; Kalaghatgi, P.; Turakhia, Y.; Corbett-Detig, R.; Quang Minh, B.; Goldman, N.: Maximum likelihood pandemic-scale phylogenetics. Nature Genetics 55, pp. 746 - 752 (2023)

Bouabid, C.; Rabhi, S.; Thedinga, K.; Barel, G.; Tnani, H.; Rabhi , I.; Benkahla, A.; Herwig, R.; Guizani-Tabbane, L.: Host M-CSF induced gene expression drives changes in susceptible and resistant mice-derived BMdMs upon Leishmania major infection. Frontiers in immunology 14, 1111072 (2023)

Messner, C. B.; Demichev, V.; Muenzner, J.; Aulakh, S. K.; Barthel, N.; Röhl, A.; Herrera-Domínguez, L.; Egger, A.-S.; Kamrad, S.; Hou, J. et al.; Tan, G.; Lemke, O.; Calvani, E.; Szyrwiel, L.; Mülleder, M.; Lilley, K. S.; Boone, C.; Kustatscher, G.; Ralser, M.: The proteomic landscape of genome-wide genetic perturbations. Cell 186 (9), pp. 2018 - 2034 (2023)

Tsaytler, P.; Liu, J.; Blaess, G.; Schifferl, D.; Veenvliet, J. V.; Wittler, L.; Timmermann, B.; Herrmann, B. G.; Koch, F.: BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage. Development, dev.201450 (2023)

Stellmach, C.; Sass, J.; Auber, B.; Boeker, M.; Wienker, T. F.; Heidel, A. J.; Benary, M.; Schumacher, S.; Ossowski, S.; Klauschen, F. et al.; Möller , Y.; Schmutzler, R.; Ustjanzew, A.; Werner, P.; Tomczak, A.; Hölter, T.; Thun, S.: Creation of a structured molecular genomics report for Germany as a local adaption of HL7's Genomic Reporting Implementation Guide. Journal of the American Medical Informatics Association, ocad061 (2023)

Hartl, J.; Kurth, F.; Kappert, K.; Horst, D.; Mülleder, M.; Hartmann, G.; Ralser, M.: Quantitative protein biomarker panels: a path to improved clinical practice through proteomics. Embo Molecular Medicine 15, e16061 (2023)

Melo, U. S.; Jatzlau, J.; Prada-Medina, C. A.; Flex, E.; Hartmann, S.; Ali, S.; Schöpflin, R.; Bernardini, L.; Ciolfi, A.; Moeinzadeh, H. et al.; Klever, M.-K.; Altay, A.; Vallecillo-García, P.; Carpentieri, G.; Delledonne, M.; Ort, M.-J.; Schwestka, M.; Battista Ferrero, G.; Tartaglia, M.; Brusco, A.; Gossen, M.; Strunk, D.; Geißler, S.; Mundlos, S.; Stricker, S.; Knaus, P.; Giorgio, E.; Spielmann, M.: Enhancer hijacking at the ARHGAP36 locus is associated with connective tissue to bone transformation. Nature Communications 14, 2034 (2023)

Kotsaris, G.; Qazi, T. H.; Bucher, C. H.; Zahid, H.; Pöhle-Kronawitter, S.; Ugorets, V.; Jarassier, W.; Börno, S.; Timmermann, B.; Giesecke-Thiel, C. et al.; Economides, A. N.; Le Grand, F.; Vallecillo-García, P.; Knaus, P.; Geissler, S.; Stricker, S.: Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors. npj Regenerative Medicine 8, 19 (2023)

Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Endosome dysfunction leads to gain-of-function TLR7 and human lupus. bioRxiv (Preprint Server) (2023)

Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 25, pp. 579 - 591 (2023)

Kibar, G.; Vingron, M.: Prediction of protein–protein interactions using sequences ofintrinsically disordered regions. Proteins: Structure, Function, and Bioinformatics, prot.26486 (2023)

Kamrad, S.; Correia-Melo, C.; Szyrwiel, L.; Kaur Aulakh, S.; Bähler, J.; Demichev, V.; Mülleder, M.; Ralser, M.: Metabolic heterogeneity and cross-feeding within isogenic yeast populations captured by DILAC. Nature Microbiology 8, pp. 441 - 454 (2023)

Pan, C.; Rahn , R.; Heller, D.; Reinert, K.: Linear: a framework to enable existing software to resolve structural variants in long reads with flexible and efficient alignment-free statistical models. Briefings in Bioinformatics 24 (2), bbad071 (2023)

Qin, B.; Lauer, S. M.; Balke, A.; Vieira-Vieira, C. H.; Bürger, J.; Mielke, T.; Selbach, M.; Scheerer, P.; Spahn, C. M. T.; Nikolay, R.: Cryo-EM captures early ribosome assembly in action. Nature Communications 14, 898 (2023)

Mensah, M. A.; Niskanen, H.; Magalhães, A. P.; Basu, S.; Kircher, M.; Sczakiel, H. L.; Reiter, A. M. V.; Elsner, J.; Meinecke, P.; Biskup, S. et al.; Chung, B. H. Y.; Dombrowsky, G.; Eckmann-Scholz, C.; Hitz, M. P.; Hoischen, A.; Holterhus, P.-M.; Hülsemann, W.; Kahrizi, K.; Kalscheuer, V. M.; Kan, A.; Krumbiegel, M.; Kurth, I.; Leubner, J.; Longardt, A. C.; Moritz, J. D.; Najmabadi, H.; Skipalova, K.; Snijders Blok, L.; Tzschach, A.; Wiedersberg, E.; Zenker, M.; Garcia-Cabau, C.; Buschow, R.; Salvatella, X.; Kraushar, M. L.; Mundlos, S.; Caliebe, A.; Spielmann, M.; Horn, D.; Hnisz, D.: Aberrant phase separation and nucleolar dysfunction in rare genetic diseases. Nature 614, pp. 564 - 571 (2023)

Le-Trilling, V. T. K.; Banchenko, S.; Paydar, D.; Leipe, P. M.; Binting, L.; Lauer, S.; Graziadei, A.; Klingen, R.; Gotthold, C.; Bürger, J. et al.; Bracht, T.; Sitek, B.; Lebbink, R. J.; Malyshkina, A.; Mielke, T.; Rappsilber, J.; Spahn, C. M. T.; Voigt, S.; Trilling, M.; Schwefel, D.: Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor. EMBO Journal 42 (5), e112351 (2023)

Palmer, E. E.; Pusch, M.; Picollo, A.; Forwood, C.; Nguyen, M. H.; Suckow, V.; Gibbons, J.; Hoff, A.; Sigfrid, L.; Megarbane, A. et al.; Nizon, M.; Cogné, B.; Beneteau, C.; Alkuraya, F. S.; Chedrawi, A.; Hashem, M. O.; Stamberger, H.; Weckhuysen, S.; Vanlander, A.; Ceulemans, B.; Rajagopalan, S.; Nunn, K.; Arpin, S.; Raynaud, M.; Motter, C. S.; Ward-Melver, C.; Janssens, K.; Meuwissen, M.; Beysen, D. ....; Kalscheuer, V. M.: Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition. Molecular Psychiatry 28, pp. 668 - 697 (2023)

Henze, L.; Braun, J.; Meyer-Arndt, L.; Jürchott, K.; Schlotz, M.; Michel, J.; Grossegesse, M.; Mangold, M.; Dingeldey, M.; Kruse, B. et al.; Holenya, P.; Mages, N.; Reimer, U.; Eckey, M.; Schnatbaum, K.; Wenschuh, H.; Timmermann, B.; Klein, F.; Nitsche, A.; Giesecke-Thiel, C.; Loyal, L.; Thiel, A.: Primary ChAdOx1 vaccination does not reactivate pre-existing, cross-reactive immunity. Frontiers in immunology 14, 1056525 (2023)

Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S. D.; Braendl, B.; Gießelmann, P. et al.; Tornisiello, R.; Mohan Parsi, K.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.: T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. eLife 12, e83077 (2023)

Binsch, C.; Barbosa, D. M.; Hansen-Dille, G.; Hubert, M.; Hodge, S. M.; Kolasa, M.; Jeruschke, K.; Weiß, J.; Springer, C.; Gorressen, S. et al.; Fischer, J. W.; Lienhard, M.; Herwig, R.; Börno, S.; Timmermann, B.; Cremer, A. L.; Backes, H.; Chadt, A.; Al-Hasani, H.: Deletion of Tbc1d4/As160 abrogates cardiac glucose uptake and increases myocardial damage after ischemia/reperfusion. Cardiovascular Diabetology 22, 17 (2023)