Publication Overview

van Jaarsveld, M. T. M.; Deng, D.; Ordoñez-Rueda, D.; Paulsen, M.; Wiemer, E. A. C.; Zi, Z.: Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest. Oncogenesis 9, 35 (2020)

Bratovič, M.; Fonfara, I.; Chylinski, K.; Gálvez, E. J. C.; Sullivan, T. J.; Boerno, S.; Timmermann, B.; Boettcher, M.; Charpentier, E.: Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches. Nature Chemical Biology 2020 (2020)

Herdt, O.; Reich, S.; Medenbach, J.; Timmermann, B.; Olofsson, D.; Preußner, M.; Heyd, F.: The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation. RNA Biology 2020 (2020)

Haltenhof, T.; Kotte, A.; De Bortoli, F.; Schiefer, S.; Meinke, S.; Emmerichs, A.-K.; Petermann, K. K.; Timmermann, B.; Imhof, P.; Franz, A. et al.; Loll, B.; Wahl, M. C.; Preußner, M.; Heyd , F.: A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Molecular Cell 2020 (2020)

Holzhütter, H.-G.; Wuensch, T.; Gajowski, R.; Berndt, N.; Bulik, S.; Meierhofer, D.; Stockmann, M.: A novel variant of the 13C-methacetin liver function breath test that eliminates the confounding effect of individual differences in sytemic CO2 kinetics. Archives of Toxicology 94 (2), pp. 401 - 415 (2020)

Kupke, S. Y.; Ly, L.-H.; Börno, S. T.; Ruff, A.; Timmermann, B.; Vingron, M.; Haas, S.: Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses 12 (1), pii: E71 (2020)

Alvarez-Dominguez, J. R.; Donaghey, J.; Rasouli, N.; Kenty, J. H. R.; Helman, A.; Charlton, J.; Straubhaar, J. R.; Meissner, A.; Melton, D. A.: Circadian Entrainment Triggers Maturation of Human In Vitro Islets. Cell Stem Cell 26 (1), e10, pp. 108 - 122 (2020)

Kolbe, E.; Aleithe, S.; Rennert, C.; Spormann, L.; Ott, F.; Meierhofer, D.; Gajowski, R.; Stöpel, C.; Hoehme, S.; Kücken, M. et al.; Brusch, L.; Seifert, M.; von Schoenfels, W.; Schafmayer, C.; Brosch, M.; Hoffmann, U.; Damm, G.; Seehofer, D.; Hampe, J.; Gebhardt, R.; Matz-Soja, M.: Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human. Cell Reports 29 (13), e7, pp. 4553 - 4567 (2019)

Grunert, M.; Appelt, S.; Dunkel, I.; Berger, F.; Sperling, S. R.: Altered microRNA and target gene expression related to Tetralogy of Fallot. Scientific Reports 9, 19063 (2019) (2019)

Hiepen, C.; Jatzlau, J.; Hildebrandt, S.; Kampfrath, B.; Goktas, M.; Murgai, A.; Cuellar Camacho, J. L.; Haag, R.; Ruppert, C.; Sengle, G. et al.; Cavalcanti-Adam, E. A.; Blank, K. G.; Knaus, P.: BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics. PLoS Biology 17 (12), e3000557 (2019)

Lammel, D. R.; Meierhofer, D.; Johnston, P.; Mbedi, S.; Rillig, M. C.: The effects of arbuscular mycorrhizal fungi (AMF) and Rhizophagus irregularis on soil microorganisms assessed by metatranscriptomics and metaproteomics. bioRxiv (Preprint-Server) (2019)

Ilik, I. A.; Aktas, T.; Maticzka, D.; Backofen, R.; Akhtar, A.: FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucelic Acids Research, gkz1141 (2019)

Gießelmann, P.; Brändl, B.; Raimondeau, E.; Bowen, R.; Rohrandt, C.; Tandon, R.; Kretzmer, H.; Assum, G.; Galonska, C.; Siebert, R. et al.; Ammerpohl, O.; Heron, A.; Schneider, S. A.; Ladewig, J.; Koch, P.; Schuldt, B. M.; Graham, J. E.; Meissner, A.; Müller, F.-J.: Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing. bioRxiv (Preprint Server), 480285 (2019)

Kottakis, F.; Nicolay, B. N.; Roumane, A.; Karnik, R.; Gu, H.; Nagle, J. M.; Boukhali, M.; Hayward, M. C.; Li, Y. Y.; Chen, T. et al.; Liesa, M.; Hammerman, P. S.; Wong, K. K.; Hayes, D. N.; Shirihai, O. S.; Dyson, N. J.; Haas, W.; Meissner, A.; Bardeesy, N.: Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 575 (7783), E5 (2019)

Sen, N.-E.; Arsovic, A.; Meierhofer, D.; Brodesser, S.; Oberschmidt, C.; Canet-Pons, J.; Kaya, Z.-E.; Halbach, M.-V.; Gispert, S.; Sandhoff, K. et al.; Auburger, G.: In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism. International Journal of Molecular Sciences 2019 (20), 5854 (2019)

Andergassen, D.; Smith, Z. D.; Lewandowski, J. P.; Gerhardinger, C.; Meissner, A.; Rinn, J. L.: In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation. eLife 8, e47214 (2019)

Ramisch, A.; Heinrich, V.; Glaser, L. V.; Fuchs, A.; Yang, X.; Benner, P.; Schöpflin, R.; Li, N.; Kinkley, S.; Römer-Hillmann, A. et al.; Longinotto, J.; Heyne, S.; Czepukojc, B.; Kessler, S. M.; Kiemer, A. K.; Cadenas, C.; Arrigoni, L.; Gasparoni, N.; Manke, T.; Pap, T.; Pospisilik, A.; Hengstler, J.; Walter, J.; Meijsing, S.; Chung, H.-R.; Vingron, M.: CRUP: a comprehensive framework to predict condition-specific regulatory units. Genome Biology: Biology for the Post-Genomic Era 20, 20:227 (2019)

Di Stefano, B.; Luo, E.-C.; Haggerty, C.; Aigner, S.; Charlton, J.; Brumbaugh, J.; Ji, F.; Rabano Jiménez, I.; Clowers, K. J.; Huebner, A. J. et al.; Clement, K.; Lipchina, I.; de Kort, M. A. C.; Anselmo, A.; Pulice, J.; Gerli, M. F. M.; Gu, H.; Gygi, S. P.; Sadreyev, R. I.; Meissner, A.; Yeo, G. W.; Hochedlinger, K.: The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell 25 (5), e13, pp. 622 - 638 (2019)

Brumbaugh , J.; Kim, I. S.; Ji, F.; Huebner, A. J.; Di Stefano , B.; Schwarz, B. A.; Charlton, J.; Coffey, A.; Choi, J.; Walsh, R. M. et al.; Schindler, J. W.; Anselmo, A.; Meissner, A.; Sadreyev, R. I.; Bernstein, B. E.; Hock, H.; Hochedlinger , K.: Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology 21 (11), pp. 1449 - 1461 (2019)

Muller, X.; Schlegel, A.; Kron, P.; Eshmuminov, D.; Würdinger, M.; Meierhofer, D.; Clavien, P.-A.; Dutkowski, P.: Novel Real-Time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation. Annals of Surgery 270 (5), pp. 783 - 790 (2019)