The Sequencing Facility is currently co-chaired on an interim basis by Prof. Dr. Alexander Meissner and Dr. Helene Kretzmer, with day-to-day operations managed by Dr. Stefan Börno. The previous head, Dr. Bernd Timmermann, has moved to industry and the search for a new Head of Sequencing is ongoing. All services and inquiries will be continued as usual.
New sequencing technologies have revolutionized genomic research over the last decade. Today, they enable researchers to investigate (epi)genomes and transcriptomes at an unexampled depth and level of detail.
Founded in 2007 the Next Generation Sequencing (NGS) Group at the Max Planck Institute for molecular Genetics is a central unit which provides its service to all research groups of the institute. Since 2010 the expertise is also provided to scientists outside the MPIMG and the group acquired the status of a Sequencing Core Facility for all institutes of the biological-medical section of the Max Planck Society.
The Sequencing Facility operates several next generation sequencers and maintains a fully equipped lab and staff able to perform a variety of sequencing applications - from sample preparation to data analysis. The NGS unit was founded to help researchers process DNA and RNA samples in an efficient and economical manner. We established automation solutions for the sample preparation to increase the throughput and minimize technical variation. By centralizing equipment and expertise, we have dramatically reduced the overall expense to the society, while increasing the efficiency and quality of the data generated.
The high throughput of our Illumina systems facilitates many applications: Single cell analysis, expression profiling (RNA-Seq), methylation analysis (WGBS, RRBS), copy number analysis as well as the identification of protein binding sites (ChIP-Seq) and the analysis of whole genomes.