- Müller lab
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood.
Am J Hum Genet. 2018 Apr 5;102(4):557-573. doi: 10.1016/j.ajhg.2018.02.014. Epub 2018 Mar 22.
Müller lab / Cellular Phenotyping Group
We explore ways to define cellular phenotypes, developmental states and disease processes with genome wide measurements. Our method spectrum spans from nanopore sequencing, signal processing and machine learning to in vitro differentiation of patient-derived pluripotent stem cells.