Übersicht der Publikationen

Zacharias, M.; Kashofer, K.; Wurm, P.; Regitnig, P.; Schütte, M.; Neger, M.; Ehmann, S.; Marsh, L. M.; Kwapiszewska, G.; Loibner, M. et al.; Birnhuber, A.; Leitner, E.; Thüringer, A.; Winter, E.; Sauer, S.; Pollheimer, M. J.; Vagena, F. R.; Lackner, C.; Jelusic, B.; Ogilvie, L.; Durdevic, M.; Timmermann, B.; Lehrach, H.; Zatloukal, K.; Gorkiewicz, G.: Host and microbiome features of secondary infections in lethal covid-19. iScience 25 (9), 104926 (2022)

Kornak, U.; Saha, N.; Keren, B.; Neumann, A.; Taylor Tavares, A. L.; Piard, J.; Kopp, J.; Rodrigues Alves, J. G.; de los Santos, M. R.; El Choubassi, N. et al.; Ehmke, N.; Jäger, M.; Spielmann, M.; Pantel, J. T.; Lejeune, E.; Fauler, B.; Mielke, T.; Hecht, J.; Meierhofer, D.; Strom, T. M.; Laugel, V.; Brice, A.; Mundlos, S.; Bertoli-Avella, A.; Bauer, P.; Heyd, F.; Boute, O.; Dupont, J.; Depienne, C.; Van Maldergem, L.; Fischer-Zirnsak, B.: Alternative splicing of BUD13 determines the severity of a developmental disorder with lipodystrophy and progeroid features. GENETICS IN MEDICINE 24 (9), S. 1927 - 1940 (2022)

Aznaourova, M.; Schmerer, N.; Janga, H.; Zhang , Z.; Pauck, K.; Bushe, J.; Volkers, S. M.; Wendisch, D.; Georg, P.; Ntini, E. et al.; Aillaud, M.; Gündisch, M.; Mack, E.; Skevaki , C.; Keller, C.; Bauer, C.; Bertrams, W.; Marsico, A.; Nist, A.; Stiewe, T.; Gruber, A. D.; Ruppert, C.; Li, Y.; Garn, H.; Sander, L. E.; Schmeck, B.; Schulte, L. N.: Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19. Proceedings of the National Academy of Sciences of the United States of America 119 (36), e2120680119 (2022)

Khilji, S. K.; Goerdeler , F.; Frensemeier, K.; Warschkau, D.; Lühle, J.; Fandi, Z.; Schirmeister, F.; Chen, Z. A.; Turak, O.; Mallagaray, A. et al.; Boerno, S.; Timmermann, B.; Rappsilber, J.; Seeberger, P. H.; Moscovitz, O.: Generation of glycan-specific nanobodies. Cell Chemical Biology 29 (8), S. 1353 - 1361 (2022)

Prasse, P.; Iversen, P.; Lienhard, M.; Thedinga, K.; Herwig, R.; Scheffer, T.: Pre-Training on In Vitro and Fine-Tuning on Patient-Derived Data Improves Deep Neural Networks for Anti-Cancer Drug-Sensitivity Prediction. Cancers / Molecular Diversity Preservation International (MDPI) 14 (16), 3950 (2022)

Boschann, F.; Cogulu, M. Ö.; Pehlivan, D.; Balachandran, S.; Vallecillo-Garcia, P.; Grochowski, C. M.; Hansmeier, N. R.; Coban Akdemir, Z. H.; Prada-Medina, C. A.; Aykut, A. et al.; Fischer-Zirnsak, B.; Badura, S.; Durmaz, B.; Ozkinay, F.; Hägerling, R.; Posey, J. E.; Stricker, S.; Gillessen-Kaesbach, G.; Spielmann, M.; Horn, D.; Brockmann, K.; Lupski, J. R.; Kornak, U.; Schmidt, J.: Biallelic variants in ADAMTS15 cause a novel form of distal arthrogryposis. GENETICS IN MEDICINE, S1098-3600(22)00849-8 (2022)

Berghöfer, J.; Khaveh, N.; Mundlos, S.; Metzger, J.: Simultaneous testing of rule- and model-based approaches for runs of homozygosity detection opens up a window into genomic footprints of selection in pigs. BMC Genomics 23, 564 (2022)

Knisbacher, B. A.; Lin, Z.; Hahn, C. K.; Nadeu, F.; Duran-Ferrer, M.; Stevenson, K. E.; Tausch, E.; Delgado, J.; Barbera-Mourelle, A.; Taylor-Weiner, A. et al.; Bousquets-Muñoz, P.; Diaz-Navarro, A.; Dunford, A.; Anand, S.; Kretzmer, H.; Gutierrez-Abril, J.; López-Tamargo, S.; Fernandes, S. M.; Sun, C.; Sivina, M.; Rassenti, L. Z.; Schneider, C.; Li, S.; Parida, L.; Meissner, A.; Aguet , F.; Burger, J. A.; Wiestner, A.; Kipps, T. J.; Brown, J. R.; Hallek, M.; Stewart, C.; Neuberg, D. S.; Martín-Subero , J. I.; Puente, X. S.; Stilgenbauer, S.; Wu, C. J.; Campo, E.; Getz, G.: Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nature Genetics (2022)

Wilder , A. P.; Dudchenko , O.; Curry , C.; Korody , M.; Turbek , S. P.; Daly, M.; Misuraca , A.; Wang, G.; Khan , R.; Weisz, D. et al.; Fronczek, J.; Lieberman Aiden , E.; Houck , M. L.; Shier , D. M.; Ryder , O. A.; Steiner , C. C.: A Chromosome-Length Reference Genome for the Endangered Pacific Pocket Mouse Reveals Recent Inbreeding in a Historically Large Population. Genome Biology and Evolution 14 (8), evac122 (2022)

Asimi, V.; Sampath Kumar, A.; Niskanen, H.; Riemenschneider, C.; Hetzel, S.; Naderi, J.; Fasching, N.; Popitsch, N.; Du, M.; Kretzmer, H. et al.; Smith, Z. D.; Weigert, R.; Walther, M.; Mamde, S.; Meierhofer, D.; Wittler, L.; Buschow, R.; Timmermann, B.; Cisse, I. I.; Ameres, S. L.; Meissner, A.; Hnisz, D.: Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 54 (8), S. 1238 - 1247 (2022)

Hudert, C. A.; Adams, L. A.; Alisi, A.; Anstee, Q. M.; Crudele, A.; Draijer, L. G.; Furse, S.; Hengstler, J. G.; Jenkins, B.; Karnebeek, K. et al.; Kelly, D. A.; Koot, B. G.; Koulman, A.; Meierhofer, D.; Melton, P. E.; Mori, T. A.; Snowden, S. G.; van Mourik, I.; Vreugdenhil, A.; Wiegand, S.; Mann, J. P.: Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17-beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms. Hepatology Communications 6 (8), S. 1934 - 1948 (2022)

Yuan, W.; Ma, S.; Brown, J. R.; Kim, K.; Murek, V.; Trastulla, L.; Meissner, A.; Lodato, S.; Shetty, A. S.; Levin, J. Z. et al.; Buenrostro, J. D.; Ziller, M. J.; Arlotta, P.: Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex. Nature Neuroscience 25 (8), S. 1049 - 1058 (2022)

Louvet, L.; Lenglet, G.; Krautzberger, A. M.; Mentaverri, R.; Hague, F.; Kowalewski, C.; Mahtal, N.; Lesieur, J.; Bonnet, A.-L.; Andrique, C. et al.; Gaucher, C.; Gomila, C.; Schrewe, H.; Tharaux, P.-L.; Kamel, S.; Chaussain, C.; Six, I.: Vasorin plays a critical role in vascular smooth muscle cells and arterial functions. Journal of Cellular Physiology (2022)

Kuhn, T.; Kaiser, K.; Lebek, S.; Altenhofen, D.; Knebel, B.; Herwig, R.; Rasche, A.; Pelligra, A.; Görigk, S.; Khuong, J. M.-A. et al.; Vogel, H.; Schürmann, A.; Blüher, M.; Chadt, A.; Al-Hasani, H.: Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene. Human Molecular Genetics 2022, ddac150 (2022)

Klimm, F.: Topological data analysis of truncated contagion maps. Chaos 32, 073108 (2022)

Mattei, A. L.; Bailly, N.; Meissner, A.: DNA methylation: a historical perspective. Trends in Genetics 38 (7), S. 676 - 707 (2022)

Heck, R.; Fischer-Zirnsak, B.; Photiadis, J.; Horn, D.; Gehle, P.: Different ascending aortic phenotypes with similar mutations in two patients with Loeys-Dietz-Syndrome type 2. Interactive CardioVascular and Thoracic Surgery 35 (1), ivac159 (2022)

Rosebrock, D.; Arora, S.; Mutukula, N.; Volkman, R.; Gralinska, E.; Balaskas, A.; Aragonés Hernández, A.; Buschow, R.; Brändl, B.; Müller, F.-J. et al.; Arndt, P. F.; Vingron, M.; Elkabetz, Y.: Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells. Nature Cell Biology 24, S. 981 - 995 (2022)

Thedinga, K.; Herwig, R.: Gradient tree boosting and network propagation for the identification of pan-cancer survival networks. STAR Protocols 3 (2), 101353 (2022)

Hilal, T.; Killam, B. Y.; Grozdanović, M.; Dobosz-Bartoszek, M.; Loerke, J.; Bürger, J.; Mielke, T.; Copeland, P. R.; Simonović, M.; Spahn, C. M. T.: Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Science 376, S. 1338 - 1343 (2022)