Übersicht der Publikationen

Krakau, S.; Richard, H.; Marsico, A.: PureCLIP: Capturing target-specific protein-RNA interaction footprints from single-nucleotide CLIP-seq data. Genome Biology 18 (1), 1:240 (2017)

Kopp, W.; Vingron, M.: An improved compound Poisson model for the number of motif hits in DNA sequences. Bioinformatics 33 (24), S. 3929 - 3937 (2017)

Regan, J. L.; Schumacher, D.; Staudte, S.; Steffen, A.; Haybaeck, J.; Keilholz, U.; Schweiger, C.; Golob-Schwarzl, N.; Mumberg, D.; Henderson, D. et al.; Lehrach, H.; Regenbrecht, C. R. A.; Schafer, R.; Lange, M.: Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells. Cell Reports 21 (10), S. 2813 - 2828 (2017)

Hector, R. D.; Kalscheuer, V. M.; Hennig, F.; Leonard, H.; Downs, J.; Clarke, A.; Benke, T. A.; Armstrong, J.; Pineda, M.; Bailey, M. E. S. et al.; Cobb, S. R.: CDKL5 variants: Improving our understanding of a rare neurologic disorder. Neurology Genetics 3 (6), e200 (2017)

Kürschner, G.; Zhang, Q.; Clima, R.; Xiao , Y.; Busch, J. F.; Kilic, E.; Jung, K.; Berndt, N.; Bulik, S.; Holzhütter, H.-G. et al.; Gasparre, G.; Attimonelli, M.; Babu, M.; Meierhofer, D.: Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione. Oncotarget 2017, 8:105882-105904 (2017)

Schulz, E. G.: X-chromosome dosage as a modulator of pluripotency, signalling and differentiation? Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 372 (1733), pii: 20160366 (2017)

Ehmke, N.; Graul-Neumann, L.; Smorag, L.; Koenig, R.; Segebrecht, L.; Magoulas, P.; Scaglia, F.; Kilic, E.; Hennig, A. F.; Adolphs, N. et al.; Saha, N.; Fauler, B.; Kalscheuer, V. M.; Hennig, F.; Altmüller, J.; Netzer, C.; Thiele, H.; Nürnberg, P.; Yigit, G.; Jäger, M.; Hecht, J.; Krüger, U.; Mielke, T.; Krawitz, P. M.; Horn, D.; Schuelke, M.; Mundlos, S.; Bacino, C. A.; Bonnen, P. E.; Wollnik, B.; Fischer-Zirnsak, B.; Kornak, U.: De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. The American Journal of Human Genetics 101 (5), S. 833 - 843 (2017)

Heller, D.; Krestel, R.; Ohler, U.; Vingron, M.; Marsico, A.: ssHMM: extracting intuitive sequence-structure motifs from high-throughput RNA-binding protein data. Nucleic Acids Research (London) 45 (19), S. 11004 - 11018 (2017)

Gardner, E. J.; Lam, V. K.; Harris, D. N.; Chuang, N. T.; Scott, E. C.; Pittard, W. S.; Mills, R. E.; 1000 Genomes Project, C.; Timmermann, B.; Devine, S. E.: The Mobile Element Locator Tool (MELT): Population-scale mobile element discovery and biology. Genome Research 27 (11), S. 1916 - 1929 (2017)

Niturad, C. E.; Lev, D.; Kalscheuer, V. M.; Charzewska, A.; Schubert, J.; Lerman-Sagie, T.; Kroes, H. Y.; Oegema, R.; Traverso, M.; Specchio, N. et al.; Lassota, M.; Chelly, J.; Bennett-Back, O.; Carmi, N.; Koffler-Brill, T.; Iacomino, M.; Trivisano, M.; Capovilla, G.; Striano, P.; Nawara, M.; Rzonca, S.; Fischer, U.; Bienek, M.; Jensen, C.; Hu, H.; Thiele, H.; Altmüller, J.; Krause, R.; May, P.; Becker, F.; Euro, E. C.; Balling, R.; Biskup, S.; Haas, S. A.; Nürnberg, P.; van Gassen, K. L. I.; Lerche, H.; Zara, F.; Maljevic, S.; Leshinsky-Silver, E.: Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features. Brain 140 (11), S. 2879 - 2894 (2017)

Vallecillo-García, P.; Orgeur, M.; vom Hofe-Schneider, S.; Stumm, J.; Kappert, V.; Ibrahim, D.; Börno, S. T.; Hayashi, S.; Relaix, F.; Hildebrandt, K. et al.; Sengle, G.; Koch, M.; Timmermann, B.; Marazzi, G.; Sassoon, D. A.; Duprez, D.; Stricker, S.: Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development. Nature Communications 8 (1), 1218 (2017)

Mutzel, V.; Okamoto, I.; Dunkel, I.; Saitou, M.; Giorgetti, L.; Heard, E.; Schulz, E. G.: Two coupled feedback loops explain random mono-allelic Xist upregulation at the onset of X-chromosome inactivation. bioRxive 2017, S. 1 - 54 (2017)

Woodsmith, J.; Apelt, L.; Casado-Medrano, V.; Özkan, Z.; Timmermann, B.; Stelzl, U.: Protein interaction perturbation profiling at amino-acid resolution. Nature methods 14 (12), S. 1213 - 1221 (2017)

Bhat, J.; Helmuth, J.; Chitadze, G.; Kouakanou, L.; Peters, C.; Vingron, M.; Ammerpohl, O.; Kabelitz, D.: Stochastics of Cellular Differentiation Explained by Epigenetics: The Case of T-Cell Differentiation and Functional Plasticity. Scand J Immunol 86 (4), S. 184 - 195 (2017)

Binder, H.; Hopp, L.; Schweiger, M. R.; Hoffmann, S.; Jühling, F.; Kerick, M.; Timmermann, B.; Siebert, S.; Grimm, C.; Nersisyan, L. et al.; Arakelyan, A.; Herberg, M.; Buske, P.; Loeffler-Wirth, H.; Rosolowski, M.; Engel, C.; Przybilla, J.; Peifer, M.; Friedrichs, N.; Moeslein, G.; Odenthal, M.; Hussong, M.; Peters, S.; Holzapfel, S.; Nattermann, J.; Hueneburg, R.; Schmiegel, W.; Royer-Pokora, B.; Aretz, S.; Kloth, M.; Kloor, M.; Buettner, R.; Galle, J.; Loeffler, M.: Genomic and transcriptomic heterogeneity of colorectal tumors arising in Lynch Syndrome. The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland 243 (2), S. 242 - 254 (2017)

Will , A. J.; Cova, G.; Osterwalder, M.; Chan, W. L.; Wittler, L.; Brieske, N.; Heinrich, V.; de Villartay, J. P.; Vingron, M.; Klopocki, E. et al.; Visel, A.; Lupianez, D. G.; Mundlos, S.: Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog). Nature Genetics 49 (10), S. 1539 - 1545 (2017)

Smith, Z. D.; Shi, J.; Gu, H.; Donaghey, J.; Clement, K.; Cacchiarelli, D.; Gnirke, A.; Michor, F.; Meissner, A.: Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature 549 (7673), S. 543 - 547 (2017)

Stumpf, P. S.; Smith, R. C. G.; Lenz, M.; Schuppert, A.; Müller, F.-J.; Babtie, A.; Chan, T. E.; Stumpf, M. P. H.; Please, C. P.; Howison, S. D. et al.; Arai, F.; MacArthur, B. D.: Stem Cell Differentiation as a Non-Markov Stochastic Process. Cell Systems 5 (3), e7, S. 268 - 282 (2017)

Reddy-Alla, S.; Böhme, M. A.; Reynolds, E.; Beis, C.; Grasskamp, A. T.; Mampell, M. M.; Maglione, M.; Jusyte, M.; Rey, U.; Babikir, H. et al.; McCarthy, A. W.; Quentin, C.; Matkovic, T.; Bergeron, D. D.; Mushtaq, Z.; Göttfert, F.; Owald, D.; Mielke, T.; Hell, S. W.; Sigrist, S. J.; Walter, A. M.: Stable positioning of Unc13 restricts synaptic vesicle fusion to defined release sites to promote synchronous neurotransmission. Neuron 95 (6), S. 1350 - 1364 (2017)

Herdt, O.; Neumann, A.; Timmermann, B.; Heyd, F.: The cancer-associated U2AF35 470A>G (Q157R) mutation creates an in-frame alternative 5’ splice site that impacts on splicing regulation in Q157R patients. RNA 2017, pii: rna.061432.117 (2017)