Publication Overview

Halecker, S.; Metzger, J.; Strube, C.; Krabben, L.; Kaufer, B.; Denner, J.: Virological and Parasitological Characterization of Mini-LEWE Minipigs Using Improved Screening Methods and an Overview of Data on Various Minipig Breeds. Microorganisms 9 (12), (12):2617 (2021)

Schifferl, D.; Scholze-Wittler, M.; Wittler, L.; Veenvliet, J. V.; Koch, F.; Herrmann, B. G.: A 37 kb region upstream of brachyury comprising a notochord enhancer is essential for notochord and tail development. Development 148 (23), dev200059 (2021)

Thedinga, K.; Herwig, R.: A gradient tree boosting and network propagation derived pan-cancer survival network of the tumor microenvironment. iScience 25 (1), 103617 (2021)

Broecker, F.; Mölling, K.: The Roles of the Virome in Cancer. Microorganisms 9 (12), 2538 (2021)

Glaser, L. V.; Steiger, M.; Fuchs, A.; van Bömmel, A.; Einfeldt, E.; Chung, H.-R.; Vingron, M.; Meijsing, S. H.: Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by FAIRE-STARR-seq. Nucleic Acids Research (London) 49 (21), gkab1100, pp. 12178 - 12195 (2021)

Geanta, M.; Tanwar, A. S.; Lehrach, H.; Satyamoorthy, K.; Brand, A.: Horizon Scanning: Rise of Planetary Health Genomics and Digital Twins for Pandemic Preparedness. OMICS: A Journal of Integrative Biology 26, 0062 (2021)

Keil, M.; Conrad, T.; Becker, M.; Keilholz, U.; Yaspo, M.-L.; Lehrach, H.; Schütte, M.; Haybaeck, J.; Hoffmann, J.: Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data. cancers 13 (23), 6018 (2021)

Kamburov, A.; Herwig, R.: ConsensusPathDB 2022: molecular interactions update as a resource for network biology. Nucleic Acids Research, gkab1128 (2021)

Hung, K. L.; Yost, K. E.; Xie, L.; Shi, Q.; Helmsauer, K.; Luebeck, J.; Schöpflin, R.; Lange, J. T.; Chamorro González, R.; Weiser, N. E. et al.; Chen, C.; Valieva, M.; Wong, I. T.-L.; Wu, S.; Dehkordi, S. R.; Duffy, C. V.; Kraft, K.; Tang, J.; Belk, J. A.; Rose, J. C.; Corces, M. R.; Granja, J. M.; Li, R.; Rajkumar, U.; Friedlein, J.; Bagchi, A.; Satpathy, A. T.; Tjian, R.; Mundlos, S.; Bafna, V.; Henssen, A. G.; Mischel, P. S.; Liu, Z.; Chang, H. Y.: ecDNA hubs drive cooperative intermolecular oncogene expression. Nature 600, pp. 731 - 736 (2021)

Enervald, E.; Powell, L. M.; Boteva, L.; Foti, R.; Ruiz, N. B.; Kibar, G.; Piszczek, A.; Cavaleri, F.; Vingron, M.; Cerase, A. et al.; Buonomo, S. B. C.: RIF1 and KAP1 differentially regulate the choice of inactive versus active X chromosomes. The EMBO Journal 40, e105862 (2021)

Blanco, M. A.; Sykes, D. B.; Gu, L.; Wu, M.; Petroni, R.; Karnik, R.; Wawer, M.; Rico, J.; Li, H.; Jacobus, W. D. et al.; Jambhekar, A.; Cheloufi, S.; Meissner, A.; Hochedlinger, K.; Scadden, D. T.; Shi, Y.: Chromatin-state barriers enforce an irreversible mammalian cell fate decision. Cell Reports 37 (6), 109967 (2021)

Andergassen, D.; Smith, Z. D.; Kretzmer, H.; Rinn, J. L.; Meissner, A.: Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages. Developmental Cell 56 (21), e4, pp. 2995 - 3005 (2021)

Hetzel, S.; Gießelmann, P.; Reinert, K.; Meissner, A.; Kretzmer, H.: RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data. Bioinformatics 37 (21), pp. 3934 - 3935 (2021)

Vowinckel , J.; Hartl, J.; Marx, H.; Kerick, M.; Runggatscher, K.; Keller, M. A.; Mülleder, M.; Day, J.; Weber, M.; Rinnerthaler, M. et al.; Yu, J. S. L.; Kaur Aulakh, S.; Lehmann, A.; Mattanovich, D.; Timmermann, B.; Zhang, N.; Dunn, C. D.; MacRae, J. I.; Breitenbach, M.; Ralser, M.: The metabolic growth limitations of petite cells lacking the mitochondrial genome. Nature Metabolism 3, pp. 1521 - 1535 (2021)

Benner, P.; Vingron, M.: Quantifying the tissue-specific regulatory information within enhancer DNA sequences. NAR: genomics and bioinformatics 3 (4), lqab095 (2021)

Melo, U. S.; Piard, J.; Fischer-Zirnsak, B.; Klever, M.-K.; Schöpflin, R.; Atta Mensah, M.; Holtgrewe, M.; Arbez-Gindre, F.; Martin, A.; Guigue, V. et al.; Gaillard, D.; Landais, E.; Roze, V.; Kremer, V.; Ramanah, R.; Cabrol, C.; Harms, F. L.; Kornak, U.; Spielmann, M.; Mundlos, S.; Van Maldergem, L.: Complete lung agenesis caused by complex genomic rearrangements with neo-TAD formation at the SHH locus. Human Genetics 140, pp. 1459 - 1469 (2021)

Kage, D.; Heinrich, K.; von Volkmann, K.; Kirsch, J.; Feher, K.; Giesecke-Thiel, C.; Kaiser , T.: Multi-angle pulse shape detection of scattered light in flow cytometry for label-free cell cycle classification. Communications Biology 4, 1144 (2021)

Heyder, N. A.; Kleinau, G.; Speck, D.; Schmidt, A.; Paisdzior, S.; Szczepek, M.; Bauer, B.; Koch, A.; Gallandi, M.; Kwiatkowski, D. et al.; Bürger, J.; Mielke, T.; Beck-Sickinger, A. G.; Hildebrand, P. W.; Spahn, C. M. T.; Hilger, D.; Schacherl, M.; Biebermann, H.; Hilal, T.; Kühnen, P.; Kobilka, B. K.; Scheerer, P.: Structures of active melanocortin-4 receptor−Gs-protein complexes with NDP-α-MSH and setmelanotide. Cell Research, 0:1–14 (2021)

Arnold, M.; Bressin, A.; Jasnovidova, O.; Meierhofer, D.; Mayer, A.: A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination. Molecular Cell 81 (17), e13, pp. 3589 - 3603 (2021)

Socha, M.; Sowińska-Seidler, A.; Melo, U. S.; Kragesteen, B. K.; Franke, M.; Heinrich, V.; Schöpflin, R.; Nagel, I.; Gruchy, N.; Mundlos, S. et al.; Sreenivasan, V. K. A.; López, C.; Vingron, M.; Bukowska-Olech, E.; Spielmann, M.; Jamsheer, A.: Position effects at the FGF8 locus are associated with femoral hypoplasia. The American Journal of Human Genetics 108 (9), pp. 1725 - 1734 (2021)