Publications of Ludovic Vallier

Traba, S. A.; Bacigalupo, L.; Fradin, D.; Talon, I.; Heidenreich, A. C.; Muraro, D.; Garcia-Bernardo, J.; Gribben , C.; Lugtu, F.; Burgos, J. I. et al.; Romero, A.; Chhatriwala, M.; Pecci, A.; Vallier, L.; Rodríguez-Seguí, S. A.: Endogenous glucocorticoid receptor activation modulates early-stage cell differentiation in pancreatic progenitors of mice and humans. Development, Article dev.204361 (2025)

Ortuño-Costela, M. C.; Pinzani, M.; Vallier, L.: Cell therapy for liver disorders: past, present and future. Nature Reviews Gastroenterology & Hepatology 22 (5), pp. 329 - 342 (2025)

Liu, H.; Yin, G.; Leonardi, B. F.; Lan, T.; Ahmed, Y. A.; Berger, H.; Kohlhepp, M. S.; Amiridze, N.; Martagón Calderón, N.; Frau, C. et al.; Vallier, L.; Rezvani, M.; Tacke, F.; Guillot, A.: Reactive cholangiocyte-derived ORM2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming. Gut, Article gutjnl-2024-334425 (2025)

Brumm, A. S.; McCarthy, A.; Gerri, C.; Fallesen, T.; Woods, L.; McMahon, R.; Papathanasiou, A.; Elder, K.; Snell, P.; Christie, L. et al.; Garcia, P.; Shaikly, V.; Taranissi, M.; Serhal, P.; Odia, R. A.; Vasilic, M.; Osnato, A.; Rugg-Gunn, P. J.; Vallier, L.; Hill, C. S.; Niakan, K. K.: Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling. Developmental Cell 60 (2), pp. 174 - 185 (2025)

Frank , A. K.; Chung, B. K.; De Novales, M. L. L.; Engesæter, L. K.; Hoyle , H. W.; Øgaard, J.; Heslop, J.; Karlsen, T. H.; Tysoe, O.; Brevini , T. et al.; Tchorz, J. S.; Vallier, L.; Mohorianu, I.; Sampaziotis, F.; Melum, E.: Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients. Digestive Diseases and Sciences 69 (10), pp. 3810 - 3823 (2024)

Frau, C.; Vallier, L.: Exploiting the plasticity of cholangiocytes to repair the biliary tree. Current Opinion in Genetics & Development 89, Article 102257 (2024)

Tan, J.; Virtue, S.; Norris, D. M.; Conway, O. J.; Yang, M.; Bidault, G. ....; Vallier, L.; Fisher-Wellman, K. H.; Frezza, C.; Vidal-Puig, A. et al.; Fazakerley, D. J.: Limited oxygen in standard cell culture alters metabolism and function of differentiated cells. The EMBO Journal 43 (11), pp. 2127 - 2165 (2024)

Gribben, C.; Galanakis, V.; Calderwood, A.; Williams, E. C.; Chazarra-Gil , R.; Larraz, M.; Frau, C.; Puengel, T.; Guillot, A.; Rouhani, F. J. et al.; Mahbubani, K.; Godfrey, E.; Davies, S. E.; Athanasiadis, E.; Saeb-Parsy, K.; Tacke, F.; Allison, M.; Mohorianu, I.; Vallier, L.: Acquisition of epithelial plasticity in human chronic liver disease. Nature 630 (8015), pp. 166 - 173 (2024)

Vilà-González, M.; Pinte, L.; Fradique, R.; Causa, E.; Kool, H.; Rodrat, M. ....; Vallier, L.: In vitro platform to model the function of ionocytes in the human airway epithelium. Respiratory Research 25 (1), Article 38664797 (2024)

Nakanoh, S.; Sham, K.; Ghimire, S.; Mohorianu, I.; Rayon, T.; Vallier, L.: Human surface ectoderm and amniotic ectoderm are sequentially specified according to cellular density. Science Advances 10 (9), Article eadh7748 (2024)

Fradique , R.; Causa, E.; Delahousse, C.; Kotar, J.; Pinte, L.; Vallier, L.; Vila-Gonzalez, M.; Cicuta , P.: Assessing motile cilia coverage and beat frequency in mammalian in vitro cell culture tissues. Royal Society Open Science 10 (8), Article 230185 (2023)

Rezvani, M.; Vallier, L.; Guillot, A.: Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and Limitations. Cellular and Molecular Gastroenterology and Hepatology 15 (5), pp. 1135 - 1145 (2023)

Brevini, T.; Maes, M.; Webb, G. J.; Fuchs, C. D.; Buescher, G.; Wang, L.; Griffiths, C.; Brown, M. L.; Scott III, W. E.; Pereyra-Gerber, P. et al.; Gelson, W. T. H.; ...; Vallier, L.; Sampaziotis, F.: FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature 615 (7950), pp. 134 - 142 (2023)

Knight-Schrijver, V. R.; Davaapil, H.; Bayraktar, S.; Ross, A. D. B.; Kanemaru, K.; Cranley, J.; Dabrowska, M.; Patel, M.; Polanski, K.; He, X. et al.; Vallier, L.; Teichmann, S.; Gambardella, L.; Sinha, S.: A single-cell comparison of adult and fetal humen epicardium defines the age-associated changes in epicardial activity. Nature Cardiovascular Research 1, pp. 1215 - 1229 (2022)

Nakanoh, S.; Kadiwala, J.; Pinte, L.; Morell, C. M.; Lenaerts, A.-S.; Vallier, L.: Simultaneous depletion of RB, RBL1 and RBL2 affects endoderm differentiation of human embryonic stem cells. PLOS ONE 17 (11), Article e0269122 (2022)

Al-Akkad, W.; Acedo, P.; Vilia, M.-G. ....; Vallier, L.; Pinzani, M.; Rombouts , K.; Mazza, G.: Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance. Cells 11 (22), Article 3652 (2022)

Speicher, A. M.; Korn, L.; Csatári, J.; Gonzalez-Cano, L.; Heming, M.; Thomas, C.; Schroeter, C. B.; Schafflick, D.; Li, X.; Gola, L. et al.; Engler, A.; Kaehne, T.; Vallier, L.; Meuth , S. G.; Meyer Zu Hörste, G.; Kovac, S.; Wiendl, H.; Schöler, H. R.; Pawlowski , M.: Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease. Proceedings of the National Academy of Sciences of the United States of America 119 (43), Article e2123476119 (2022)

Wesley, B. T.; Ross, A. D. B.; Muraro, D.; Miao, Z.; Saxton, S.; Tomaz, R. A.; Morell, C. M.; Ridley, K.; Zacharis, E. D.; Petrus-Reurer, S. et al.; ...; Vallier, L.: Single-cell atlas of human liver development reveals pathways directing hepatic cell fates. Nature Cell Biology 24 (10), pp. 1487 - 1498 (2022)

Jowett, G. M.; Read, E.; Roberts, L. B.; Coman, D.; Vilà González, M.; Zabinski, T.; Niazi, U.; Reis, R.; Trieu, T.-J.; Danovi, D. et al.; Gentleman, E.; Vallier, L.; Curtis, M. A.; Lord , G. M.; Neves, J. F.: Organoids capture tissue-specific innate lymphoid cell development in mice and humans. Cell Reports 40 (9), Article 111281 (2022)

Tomaz, R. A.; Zacharis, E. D.; Bachinger, F.; Wurmser, A. ....; Vallier, L.: Generation of functional hepatocytes by forward programming with nuclear receptors. eLife 11, Article e71591 (2022)