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Journal Article (40)

1.

MPG.PuRe

DOI

publisher-version

Journal Article
Tsankov, A. M.; Wadsworth, M. H.; Akopian, V.; Charlton, J.; Allon, S. J.; Arczewska, A. A.; Mead, B. E.; Drake, R. S.; Smith, Z. D.; Mikkelsen, T. S. et al.; Shalek, A. K.; Meissner, A.: Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development 2019 (2019)
2.

MPG.PuRe

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publisher-version

supplementary-material

Journal Article
Giesselmann, P.; Hetzel, S.; Müller, F.-J.; Meissner, A.; Kretzmer, H.: Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 2019 (2019)
3.

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publisher-version

Journal Article
Modic, M.; Grosch, M.; Rot, G.; Schirge, S.; Lepko, T.; Yamazaki, T.; Lee, F. C. Y.; Rusha, E.; Shaposhnikov, D.; Palo, M. et al.; Merl-Pham, J.; Cacchiarelli, D.; Rogelj, B.; Hauck, S. M.; von Mering, C.; Meissner, A.; Lickert, H.; Hirose, T.; Drukker, M.: Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell 74 (5), e13, pp. 951 - 965 (2019)
4.

MPG.PuRe

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publisher-version

Journal Article
Chan, M. M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T. M.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Jones, M. G. et al.; Khodaverdian, A.; Nir, Y.; Meissner, A.; Weissman, J. S.: Molecular recording of mammalian Embryogenesis. Nature 570 (7759), pp. 77 - 82 (2019)
5.

MPG.PuRe

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publisher-version

Journal Article
Gaiti, F.; Chaligne, R.; Gu, H.; Brand, R. M.; Kothen-Hill, S.; Schulman, R. C.; Grigorev, K.; Risso, D.; Kim, K.-T.; Pastore, A. et al.; Huang, K. Y.; Alonso, A.; Sheridan, C.; Omans, N. D.; Biederstedt, E.; Clement, K.; Wang, L.; Felsenfeld, J. A.; Bhavsar, E. B.; Aryee, M. J.; Allan, J. N.; Furman, R.; Gnirke, A.; Wu, C. J.; Meissner, A.; Landau, D. A.: Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 569 (7757), pp. 576 - 580 (2019)
6.

MPG.PuRe

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publisher-version

Journal Article
Pastore, A.; Gaiti, F.; Lu, S. X.; Brand, R. M.; Kulm, S.; Chaligne, R.; Gu, H.; Huang, K. Y.; Stamenova, E. K.; Béguelin, W. et al.; Jiang, Y.; chulman, R. C.; Kim, K.-T.; Alonso, A.; Allan, J. N.; Furman, R. R.; Gnirke, A.; Wu, C. J.; Melnick, A. M.; Meissner, A.; Bernstein, B. E.; Abdel-Wahab, O.; Landau, D. A.: Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications 10 (1) (2019)
7.

MPG.PuRe

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Full

Journal Article
Hinohara, K.; Wu, H.-J.; Vigneau, S.; McDonald, T. O.; Igarashi, K. J.; Yamamoto, K. N.; Madsen, T.; Fassl, A.; Egri, S. B.; Papanastasiou, M. et al.; Ding, L.; Peluffo, G.; Cohen, O.; Kales, S. C.; Lal-Nag, M.; Rai, G.; Maloney, D. J.; Jadhav, A.; Simeonov, A.; Wagle, N.; Brown, M.; Meissner, A.; Sicinski, P.; Jaffe, J. D.; Jeselsohn, R.; Gimelbrant, A. A.; Michor, F.; Polyak, K.: KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell 35 (2), pp. 330 - 332 (2019)
8.

MPG.PuRe

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publisher-version

Journal Article
Klein, H.-U.; McCabe, C.; Gjoneska, E.; Sarah E. Sullivan, S. E.; Kaskow, B. J.; Tang, A.; Smith, R. V.; Xu, J.; Pfenning, A. R.; Bernstein, B. E. et al.; Meissner, A.; Schneider, J. A.; Mostafavi, S.; Tsai, L.-H.; Young-Pearse, T. L.; Bennett, D. A.; De Jager, P. L.: Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience 22 (1), pp. 37 - 46 (2019)
9.

MPG.PuRe

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pre-print

Journal Article
Gießelmann, P.; Brändl, B.; Raimondeau, E.; Bowen, R.; Rohrandt, C.; Tandon, R.; Kretzmer, H.; Assum, G.; Galonska, C.; Siebert, R. et al.; Ammerpohl, O.; Heron, A.; Schneider, S. A.; Ladewig, J.; Koch, P.; Schuldt, B. M.; Graham, J. E.; Meissner, A.; Müller, F.-J.: Repeat expansion and methylation state analysis with nanopore sequencing. bioRxiv (Preprint Server) (2018)
10.

MPG.PuRe

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publisher-version

Journal Article
Zhang, Y.; Charlton, J.; Karnik, R.; Beerman, I.; Smith, Z. D.; Gu, H.; Boyle, P.; Mi , X.; Clement, K.; Pop, R. et al.; Gnirke, A.; Rossi, D. J.; Meissner, A.: Targets and genomic constraints of ectopic Dnmt3b expression. eLife 7 (2018)
11.

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publisher-version

Journal Article
Ichida, J. K.; Staats, K. A.; Davis-Dusenbery, B. N.; Clement, K.; Galloway, K. E.; Babos, K. N.; Shi, Y.; Son, E. Y.; Kiskinis, E.; Atwater, N. et al.; Gu, H.; Gnirke, A.; Meissner, A.; Eggan, K.: Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development 145 (22) (2018)
12.

MPG.PuRe

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correspondence

Journal Article
Bernstein, E.; Meissner, A.; Ramalho-Santos, M.: Paying PIs from grants blocks talent and diversity. Nature 563 (7731), p. 325 (2018)
13.

MPG.PuRe

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publisher-version

Journal Article
Rajavelu, A.; Lungu, C.; Emperle, M.; Dukatz, M.; Bröhm, A.; Broche, J.; Hanelt, I.; Parsa, E.; Schiffers, S.; Karnik, R. et al.; Meissner, A.; Carell, T.; Rathert, P.; Jurkowska, R. Z.; Jeltsch, A.: Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research (London) 46 (17), pp. 9044 - 9056 (2018)
14.

MPG.PuRe

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publisher-version

Journal Article
Cacchiarelli, D.; Qiu, X.; Srivatsan, S.; Manfredi, A.; Ziller, M.; Overbey, E.; Grimaldi, A.; Grimsby, J.; Pokharel, P.; Livak, K. J. et al.; Li, S.; Meissner, A.; Mikkelsen, T. S.; Rinn, J. L.; Trapnell, C.: Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome. Cell Systems 7 (3), e3, pp. 258 - 268 (2018)
15.

MPG.PuRe

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publisher-version

Journal Article
Di Stefano, B.; Ueda, M.; Sabri, S.; Brumbaugh, J.; Huebner, A. J.; Sahakyan, A.; Clement, K.; Clowers, K. J.; Erickson, A. R.; Shioda, K. et al.; Gygi, S. P.; Gu, H.; Shioda, T.; Meissner, A.; Takashima, Y.; Plath, K.; Hochedlinger, K.: Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature methods 15 (9), pp. 732 - 740 (2018)
16.

MPG.PuRe

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publisher-version

Journal Article
Schwarz, B. A.; Cetinbas, M.; Clement, K.; Walsh, R. M.; Cheloufi, S.; Gu, H.; Langkabel, J.; Kamiya, A.; Schorle, H.; Meissner, A. et al.; Sadreyev, R. I.; Hochedlinger, K.: Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming. Cell Stem Cell 23 (2), e5, pp. 289 - 305 (2018)
17.

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publisher-version

Journal Article
Nehme, R.; Zuccaro, E.; Ghosh, S. D.; Li, C.; Sherwood, J. L.; Pietilainen, O.; Barrett, L. E.; Limone, F.; Worringer, K. A.; Kommineni, S. et al.; Zang, Y.; Cacchiarelli, D.; Meissner, A.; Adolfsson, R.; Haggarty, S.; Madison, J.; Muller, M.; Arlotta, P.; Fu, Z.; Feng, G.; Eggan, K.: Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Reports 23 (8) (2018)
18.

MPG.PuRe

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publisher-version

Journal Article
Pasque, V.; Karnik, R.; Chronis, C.; Petrella, P.; Langerman, J.; Bonora, G.; Song, J.; Vanheer, L.; Dimashkie, A. S.; Meissner, A. et al.; Plath, K.: X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports 10 (5), pp. 1537 - 1550 (2018)
19.

MPG.PuRe

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publisher-version

Journal Article
Shukla, S. A.; Bachireddy, P.; Schilling, B.; Galonska, C.; Zhan, Q.; Bango, C.; Langer, R.; Lee, P. C.; Gusenleitner, D.; Keskin, D. B. et al.; Babadi, M.; Mohammad, A.; Gnirke, A.; Clement, K.; Cartun, Z. J.; Van Allen, E. M.; Miao, D.; Huang, Y.; Snyder, A.; Merghoub, T.; Wolchok, J. D.; Garraway, L. A.; Meissner, A.; Weber, J. S.; Hacohen, N.; Neuberg, D.; Potts, P. R.; Murphy, G. F.; Lian, C. G.; Schadendorf, D.; Hodi, F. S.; Wu, C. J.: Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell 173 (3) (2018)
20.

MPG.PuRe

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publisher-version

Journal Article
Cesana, M.; Guo, M. H.; Cacchiarelli, D.; Wahlster, L.; Barragan, J.; Doulatov, S.; Vo, L. T.; Salvatori, B.; Trapnell, C.; Clement, K. et al.; Cahan, P.; Tsanov, K. M.; Sousa, P. M.; Tazon-Vega, B.; Bolondi, A.; Giorgi, F. M.; Califano, A.; Rinn, J. L.; Meissner, A.; Hirschhorn, J. N.; Daley, G. Q.: A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell 22 (4) (2018)