Publications of David Meierhofer

Journal Article (86)

1.
Journal Article
Ilik, I. A.; Glažar, P.; Tse, K.; Brändl, B.; Meierhofer, D.; Müller, F.-J.; Smith, Z. D.; Aktas, T.: Autonomous transposons tune their sequences to ensure somatic suppression. Nature 626 (8001), pp. 1116 - 1124 (2024)
2.
Journal Article
Kudrin, P.; Singh, A.; Meierhofer, D.; Kuśnierczyk, A.; Ørom, U. A. V.: N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules. EMBO Reports (2024)
3.
Journal Article
Key, J.; Gispert, S.; Reddy Kandi , A.; Heinz, D.; Hamann, A.; Osiewacz, H. D.; Meierhofer, D.; Auburger, G.: CLPP-Null Eukaryotes with Excess Heme Biosynthesis Show Reduced L-arginine Levels, Probably via CLPX-Mediated OAT Activation. Biomolecules 14 (2), 241 (2024)
4.
Journal Article
Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Disrupted degradative sorting of TLR7 is associated with human lupus. Science Immunology, eadi9575 (2024)
5.
Journal Article
van der Weijden, V. A.; Stötzel, M.; Iyer, D. P.; Fauler, B.; Gralinska, E.; Shahraz, M.; Meierhofer, D.; Vingron, M.; Rulands, S.; Alexandrov, T. et al.; Mielke, T.; Bulut-Karslioglu, A.: FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy. Nature Cell Biology (2024)
6.
Journal Article
Basu, S.; Martínez-Cristóbal, P.; Frigolé-Vivas, M.; Pesarrodona, M.; Lewis, M.; Szulc, E.; Bañuelos, C. A.; Sánchez-Zarzalejo, C.; Bielskutė, S.; Zhu, J. et al.; Pombo-García, K.; Garcia-Cabau, C.; Zodi, L.; Dockx, H.; Smak, J.; Kaur, H.; Batlle, C.; Mateos, B.; Biesaga, M.; Escobedo, A.; Bardia, L.; Verdaguer, X.; Ruffoni, A.; Mawji, N. R.; Wang, J.; Obst, J. K.; Tam, T.; Brun-Heath, I.; Ventura, S.; Meierhofer, D.; García, J.; Robustelli, P.; Stracker, T. H.; Sadar, M. D.; Riera, A.; Hnisz, D.; Salvatella, X.: Rational optimization of a transcription factor activation domain inhibitor. Nature Structural & Molecular Biology 30 (12), pp. 1958 - 1969 (2023)
7.
Journal Article
Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Endosome dysfunction leads to gain-of-function TLR7 and human lupus. bioRxiv (Preprint Server) (2023)
8.
Journal Article
Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 25, pp. 579 - 591 (2023)
9.
Journal Article
Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S. D.; Braendl, B.; Gießelmann, P. et al.; Tornisiello, R.; Mohan Parsi, K.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.: T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. eLife 12, e83077 (2023)
10.
Journal Article
Shahryari, M.; Keller, S.; Meierhofer, D.; Wallach, I.; Safraou, Y.; Guo, J.; Marticorena Garcia, S. R.; Braun, J.; Makowski, M. R.; Sack, I. et al.; Berndt, N.: On the relationship between metabolic capacities and in vivo viscoelastic properties of the liver. Frontiers in Bioengineering and Biotechnology 10, 1042711 (2023)
11.
Journal Article
Witt, N.; Galante, D.; Andreotti, S.; Glil, M. A.; Fasanella, A.; Meierhofer, D.; Tomaso, H.: Identification of Universally Applicable and Species-Specific Marker Peptides for Bacillus anthracis. Life 12 (10), 1549 (2022)
12.
Journal Article
Berndt, N.; Hudert, C. A.; Eckstein, J.; Loddenkemper, C.; Henning, S.; Bufler, P.; Meierhofer, D.; Sack, I.; Wiegand, S.; Wallach, I. et al.; Holzhütter, H.-G.: Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences 23 (19), 11072 (2022)
13.
Journal Article
Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S.; Braendl, B.; Giesselmann, P. et al.; Tornisiello, R.; Mohan Parsi, K.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.: Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation. bioRxiv (Preprint Server) (accepted)
14.
Journal Article
Kornak, U.; Saha, N.; Keren, B.; Neumann, A.; Taylor Tavares, A. L.; Piard, J.; Kopp, J.; Rodrigues Alves, J. G.; de los Santos, M. R.; El Choubassi, N. et al.; Ehmke, N.; Jäger, M.; Spielmann, M.; Pantel, J. T.; Lejeune, E.; Fauler, B.; Mielke, T.; Hecht, J.; Meierhofer, D.; Strom, T. M.; Laugel, V.; Brice, A.; Mundlos, S.; Bertoli-Avella, A.; Bauer, P.; Heyd, F.; Boute, O.; Dupont, J.; Depienne, C.; Van Maldergem, L.; Fischer-Zirnsak, B.: Alternative splicing of BUD13 determines the severity of a developmental disorder with lipodystrophy and progeroid features. GENETICS IN MEDICINE 24 (9), pp. 1927 - 1940 (2022)
15.
Journal Article
Asimi, V.; Sampath Kumar, A.; Niskanen, H.; Riemenschneider, C.; Hetzel, S.; Naderi, J.; Fasching, N.; Popitsch, N.; Du, M.; Kretzmer, H. et al.; Smith, Z. D.; Weigert, R.; Walther, M.; Mamde, S.; Meierhofer, D.; Wittler, L.; Buschow, R.; Timmermann, B.; Cisse, I. I.; Ameres, S. L.; Meissner, A.; Hnisz, D.: Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 54, pp. 1238 - 1247 (2022)
16.
Journal Article
Hudert, C. A.; Adams, L. A.; Alisi, A.; Anstee, Q. M.; Crudele, A.; Draijer, L. G.; EU-PNAFLD, I.; Furse, S.; Hengstler, J. G.; Jenkins, B. et al.; Karnebeek, K.; Kelly, D. A.; Koot, B. G.; Koulman, A.; Meierhofer, D.; Melton, P. E.; Mori, T. A.; Snowden, S. G.; van Mourik, I.; Vreugdenhil, A.; Wiegand, S.; Mann, J. P.: Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17- beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms. Hepatology Communications 6 (8), pp. 1934 - 1948 (2022)
17.
Journal Article
Koutsoumparis, A.; Welp, L.; Wulf, A.; Urlaub, H.; Meierhofer, D.; Börno, S.; Timmermann, B.; Busack, I.; Bringmann, H.: Sleep neuron depolarization promotes protective gene expression changes and FOXO activation. Current Biology 32 (10), pp. 2248 - 2262 (2022)
18.
Journal Article
Arnold, M.; Bressin, A.; Jasnovidova, O.; Meierhofer, D.; Mayer, A.: A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination. Molecular Cell 81 (17), e13, pp. 3589 - 3603 (2021)
19.
Journal Article
Jiao, L.; Eickhoff, R.; Egners, A.; Jumpertz , S.; Roth, J.; Erdem, M.; Kroh, A.; Duimel, H.; López-Iglesias, C.; Caro, P. et al.; Heij, L. R.; Schmeding, M.; Meierhofer, D.; Neumann, U. P. ..; Cramer, T.: Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer. The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland, 5768 (2021)
20.
Journal Article
Haggerty, C.; Kretzmer, H.; Riemenschneider, C.; Sampath Kumar, A.; Mattei, A. L.; Bailly, N.; Gottfreund, J.; Giesselmann, P.; Weigert, R.; Brändl, B. et al.; Giehr, P.; Buschow, R.; Galonska, C.; von Meyenn, F.; Pappalardi, M. B.; McCabe, M. T.; Wittler, L.; Giesecke-Thiel, C.; Mielke, T.; Meierhofer, D.; Timmermann, B.; Müller, F.-J.; Walter, J.; Meissner, A.: Dnmt1 has de novo activity targeted to transposable elements. Nature Structural and Molecular Biology 2021 (2021)
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