Publications of M. Ralser

Breitenbach, M.; Laun, P.; Dickinson, J. R.; Klocker, A.; Rinnerthaler, M.; Dawes, I. W.; Aung-Htut, M. T.; Breitenbach-Koller, L.; Caballero, A.; Nystrom, T. et al.; Buttner, S.; Eisenberg, T.; Madeo, F.; Ralser, M.: The role of mitochondria in the aging processes of yeast. Sub-Cellular Biochemistry 57, pp. 55 - 78 (2012)

Habermann, K.; Mirgorodskaya, E.; Gobom, J.; Lehmann, V.; Müller, H.; Blümlein, K.; Deery, M. J.; Czogiel, I.; Erdmann, C.; Ralser, M. et al.; von Kries, J. P.; Lange, B. M. H.: Functional analysis of centrosomal kinase substrates in Drosophila melanogaster reveals a new function of the nuclear envelope component otefin in cell cycle progression. Molecular and Cellular Biology (Washington, DC) 32 (17), pp. 3554 - 3569 (2012)

Ralser, M.; Michel, S.; Breitenbach, M.: Sirtuins as regulators of the yeast metabolic network. Frontiers in Pharmacology 3, 3:32 (2012)

Hallen, L.; Klein, H.; Stoschek, C.; Wehrmeyer, S.; Nonhoff, U.; Ralser, M.; Wilde, J.; Rohr, C.; Schweiger, M. R.; Zatloukal, K. et al.; Vingron, M.; Lehrach, H.; Konthur, Z.; Krobitsch, S.: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Human Molecular Genetics 20, pp. 104 - 114 (2011)

Bluemlein, K.; Gruning, N. M.; Feichtinger, R. G.; Lehrach, H.; Kofler, B.; Ralser, M.: No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis. Oncotarget 2 (5), pp. 393 - 400 (2011)

Bluemlein, K.; Ralser, M.: Monitoring protein expression in whole-cell extracts by targeted label- and standard-free LC-MS/MS. Nature Protocols 6 (6), pp. 859 - 69 (2011)

Gruning, N. M.; Ralser, M.: Cancer: Sacrifice for survival. Nature 480 (7376), pp. 190 - 1 (2011)

Gruning, N. M.; Rinnerthaler, M.; Bluemlein, K.; Mulleder, M.; Wamelink, M. M.; Lehrach, H.; Jakobs, C.; Breitenbach, M.; Ralser, M.: Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell Metabolism 14 (3), pp. 415 - 27 (2011)

Kruger, A.; Gruning, N. M.; Wamelink, M. M.; Kerick, M.; Kirpy, A.; Parkhomchuk, D.; Bluemlein, K.; Schweiger, M. R.; Soldatov, A.; Lehrach, H. et al.; Jakobs, C.; Ralser, M.: The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Antioxidants & Redox Signaling 15 (2), pp. 311 - 24 (2011)

Kruger, A.; Ralser, M.: ATM is a redox sensor linking genome stability and carbon metabolism. Science Signaling 4 (167), p. pe17 (2011)

Prigione, A.; Lichtner, B.; Kuhl, H.; Struys, E. A.; Wamelink, M.; Lehrach, H.; Ralser, M.; Timmermann, B.; Adjaye, J.: Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Stem Cells 29 (9), pp. 1338 - 48 (2011)

Timmermann, B.; Jarolim, S.; Russmayer, H.; Kerick, M.; Michel, S.; Krüger, A.; Bluemlein, K.; Laun, P.; Grillari, J.; Lehrach, H. et al.; Breitenbach, M.; Ralser, M.: A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. Aging (Albany NY) 2 (8), pp. 475 - 486 (2010)

Wamelink, M. M.; Gruning, N. M.; Jansen, E. E.; Bluemlein, K.; Lehrach, H.; Jakobs, C.; Ralser, M.: The difference between rare and exceptionally rare: molecular characterization of ribose 5-phosphate isomerase deficiency. Journal of Molecular Medicine 88 (9), pp. 931 - 939 (2010)

Gruning, N. M.; Lehrach, H.; Ralser, M.: Regulatory crosstalk of the metabolic network. Trends in Biochemical Sciences 35 (4), pp. 220 - 227 (2010)

Ralser, M.; Wamelink, M. M. C.; Latkolik, S.; Jansen, E. E. W.; Lehrach, H.; Jakobs, C.: Correspondence: Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response. Nature biotechnology 27 (7), pp. 604 - 605 (2009)

Ralser, M.; Zeidler, U.; Lehrach, H.: Interfering with Glycolysis Causes Sir2-Dependent Hyper-Recombination of Saccharomyces cerevisiae Plasmids. PLoS ONE 4 (4), p. e5376 - e5376 (2009)

Ralser, M.; Wamelink, M. M.; Struys, E. A.; Joppich, C.; Krobitsch, S.; Jakobs, C.; Lehrach, H.: A catabolic block does not sufficiently explain how 2-deoxy-d-glucose inhibits cell growth. Proceedings of the National Academy of Sciences of the United States of America (Washington, DC) 105 (46), pp. 17807 - 17811 (2008)

Ralser, M.; Benjamin, I. J.: Reductive stress on life span extension in C. elegans. BMC Research Notes 1, p. 1:19 - 1:19 (2008)

Ralser, M.; Nebel, A.; Kleindorp, R.; Krobitsch, S.; Lehrach, H.; Schreiber, S.; Reinhardt, R.; Timmermann, B.: Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans. BMC Genetics 9, p. 9:38 - 9:38 (2008)

Ralser, M.; Nebel, A.; Kleindorp, R.; Krobitsch, S.; Lehrach, H.; Schreiber, S.; Reinhardt, R.; Timmermann, B.: Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans. BMC Genetics 9, p. 9:38 - 9:38 (2008)