Publications of Rainer Spang

Odoardi, F.; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D.; Heckelsmiller, K.; Nietfeld, W.; Ellwart, J.; Klinkert, W. E. F. et al.; Lottaz, C.; Nosov, M.; Brinkmann, V.; Spang, R.; Lehrach, H.; Vingron, M.; Wekerle, H.; Fluegel-Koch, C.; Fluegel, A.: T cells become licensed in the lung to enter the central nervous system. Nature 488 (7413), pp. 675 - 679 (2012)

Kostka, D.; Spang, R.: Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures. PLoS Computational Biology 4 (2), p. e22 - e22 (2008)

Jacob, J.; Jentsch, M.; Kostka, D.; Bentink, S.; Spang, R.: Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs. Bioinformatics 24 (7), pp. 995 - 1001 (2008)

Markowetz, F.; Spang, R.: Inferring cellular networks – a review. BMC Bioinformatics 8 (Suppl 6), p. S5 - S5 (2007)

Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F.E.; Bernd, H.-W.; Cogliatti, S. B.; Dierlamm, J.; Feller, A. C. et al.; Hansmann, M.-L.; Haralambieva, E.; Harder, L.; Hasenclever, D.; Kühn, M.; Lenze, D.; Lichter, P.; Martin-Subero, J. I.; Möller, P.; Müller-Hermelink, H.-K.; Ott, G.; Parwaresch, R. M.; Pott, C.; Rosenwald, A.; Rosolowski, M.; Schwaenen, C.; Stürzenhofecker, B.; Szczepanowski, M.; Trautmann, H.; Wacker, H.-H.; Spang, R.; Loeffler, M.; Trümper, L.; Stein, H.; Siebert, R.: A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling. The New England Journal of Medicine: NEJM / Publ. by the Massachusetts Medical Society 354 (23), pp. 2419 - 2430 (2006)

Markowetz, F.; Bloch, J.; Spang, R.: Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinformatics 21, pp. 4026 - 4032 (2005)

Yang, X.; Bentink, S.; Spang, R.: Detecting common gene expression patterns in multiple cancer outcome entities. Biomedical Microdevices 7 (3), pp. 247 - 251 (2005)

Lottaz, C.; Spang, R.: stam - a Bioconductor compliant R package for structured analysis of microarray data. BMC Bioinformatics 6 (1), pp. 1971 - 1978 (2005)

Jaeger, J.; Weichenhan, D.; Ivandic, B.; Spang, R.: Early diagnostic marker panel determination for microarray based clinical studies. Statistical Applications in Genetics and Molecular Biology 4 (1), p. Article 9 - Article 9 (2005)

Scheid, S.; Spang, R.: twilight; a Bioconductor package for estimating the local false discovery rate. Bioinformatics 21 (12), pp. 2921 - 2922 (2005)

Lottaz, C.; Spang, R.: Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data. Bioinformatics 21 (9), pp. 1971 - 1978 (2005)

Markowetz, F.; Spang, R.: Molecular diagnosis: classification, model selection, and performance evaluation. Methods of Information in Medicine 44 (3), pp. 438 - 443 (2005)

Scheid, S.; Spang, R.: A stochastic downhill search algorithm for estimating the local false discovery rate. IEEE ACM Transactions on Computational Biology and Bioinformatics 1 (3), pp. 98 - 108 (2004)

Grzeskowiak, R.; Witt, H.; Drungowski, M.; Thermann, R.; Hennig, S.; Perrot, A.; Osterziel, K. J.; Klingbiel, D.; Scheid, S.; Spang, R. et al.; Lehrach, H.; Ruiz, P.: Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovascular Research 59 (2), pp. 400 - 411 (2003)

Spang, R.: Diagnostic signatures from microarrays: a bioinformatics concept for personalized medicine. BIOSILICO 1 (2), pp. 64 - 68 (2003)

Spang, R.; Rehmsmeier, M.; Stoye, J.: A novel approach to remote homology detection: jumping alignments. Journal of Computational Biology 9 (5), pp. 747 - 760 (2002)

Spang, R.; Zuzan, H.; West, M.; Nevins, J.; Blanchette, C.; Marks, J. R.: Prediction and uncertainty in the analysis of gene expression profiles. GCB ' 01, p. 0033 - 0033 (2002)

Müller, T.; Spang, R.; Vingron, M.: Estimating Amino Acid Substitution Models: A Comparison of Dayhoff's Estimator, the Resolvent Approach and a Maximum Likelihood Method. Molecular Biology and Evolution 19 (1), pp. 8 - 13 (2002)

Scheid, S.; Spang, R.: Microarray Data Analysis: Differential gene expression. In: DNA Microarrays, pp. 227 - 239 (Eds. Nuber; Ulrike). Garland Science, New York (2005)

Markowetz, F.; Grossmann, S.; Spang, R.: Probabilistic soft interventions in Conditional Gaussian networks. In: Artificial Intelligence and Statistics, pp. 214 - 221. Tenth International Workshop on Artificial Intelligence and Statistics, Barbados, January 06, 2005 - January 08, 2005. Society for Artificial Intelligence and Statistics, New Jersey, USA (2005)