Funding for a master or PhD position is available (2 years with the possibility of extension for another year). Please submit your motivation letter and CV.
Topic:
The area of interest of the Meierhofer group lies in the field of renal cell carcinoma (RCC) and its subtypes.
A brand new timsTOF SCP mass spectrometer (Bruker) will be used to study the spatial proteome at or near single-cell resolution. Metabolic differences, epigenetic marks, and post-translational modifications between adjacent healthy kidney tissues and RCC are waiting to be discovered by a master or doctoral student combining wet lab and computational molecular biology.
Furthermore, organoids, grown from patient derived single cancer cells will be analyzed on a single cell level to shed light on the progression, development, and heterogeneity of RCC. You are welcome to address own research questions in this area.