Publications of Bernd Timmermann

Veenvliet, J. V.; Bolondi, A.; Kretzmer, H.; Haut, L.; Scholze-Wittler, M.; Schifferl, D.; Koch, F.; Guignard, L.; Sampath Kumar, A.; Pustet, M. et al.; Heimann, S.; Buschow, R.; Wittler, L.; Timmermann, B.; Meissner, A.; Herrmann, B. G.: Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 370 (6522), eaba4937 (2020)

Neumann, A.; Meinke, S.; Goldammer, G.; Strauch, M.; Schubert, D.; Timmermann, B.; Heyd, F.; Preußner, M.: Alternative splicing coupled mRNA decay shapes the temperature‐dependent transcriptome. EMBO Reports 21 (12), e51369 (2020)

Xiao, Y.; Rabien, A.; Buschow, R.; Amstislavskiy, V.; Busch, J.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Schütte, M.; Mielke, T. et al.; Yaspo, M.-L.; Jung, K.; Meierhofer, D.: Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research 80, pp. 5491 - 5501 (2020)

Wei, X.; Franke, J.; Ost, M.; Wardelmann, K.; Börno, S.; Timmermann, B.; Meierhofer, D.; Kleinridders, A.; Klaus, S.; Stricker, S.: Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis. Journal of Cachexia, Sarcopenia and Muscle 2020, 12632 (2020)

Selevsek, N.; Caiment, F.; Nudischer, R.; Gmuender, H.; Agarkova, I.; Atkinson, F. L.; Bachmann, I.; Baier, V.; Barel, G.; Bauer, C. et al.; Boerno, S.; Bosc, N.; Clayton, O.; Cordes, H.; Deeb, S.; Gotta, S.; Guye, P.; Hersey, A.; Hunter, F. M. I.; Kunz, L.; Lewalle, A.; Lienhard, M.; Merken, J.; Minguet, J.; Oliveira, B.; Pluess, C.; Sarkans, U.; Schrooders, Y.; Schuchhardt, J.; Smit, I.; Thiel, C.; Timmermann, B.; Verheijen, M.; Wittenberger, T.; Wolski, W.; Zerck, A.; Heymans, S.; Kuepfer, L.; Roth, A.; Schlapbach, R.; Niederer, S.; Herwig, R.; Kleinjans, J.: Network integration and modelling of dynamic drug responses at multi-omics levels. Communications Biology 3 (1), 573 (2020)

Real, F. M.; Haas, S. A.; Franchini, P.; Xiong, P.; Simakov, O.; Kuhl, H.; Schöpflin, R.; Heller, D.; Moeinzadeh, M. H.; Heinrich, V. et al.; Krannich , T.; Bressin, A.; Hartmann, M. F.; Wudy, S. A.; Dechmann, D. K. N.; Hurtado, A.; Barrionuevo, F. J.; Schindler, M.; Harabula, I.; Osterwalder, M.; Hiller, M.; Wittler, L.; Visel, A.; Timmermann, B.; Meyer, A.; Vingron, M.; Jiménez, R.; Mundlos, S.; Lupiáñez, D. G.: The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. Science 370 (6513), pp. 208 - 214 (2020)

Aparicio-Soto, M.; Riedel, F.; Leddermann, M.; Bacher, P.; Scheffold, A.; Kuhl, H.; Timmermann, B.; Chudakov, D. M.; Molin, S.; Worm, M. et al.; Heine, G.; Thierse, H.-J.; Luch, A.; Siewert, K.: TCRs with segment TRAV9-2 or a CDR3 histidine are overrepresented among nickel-specific CD4+ T cells. Allergy 75 (10), pp. 2574 - 2586 (2020)

Grosswendt, S.; Kretzmer, H.; Smith, Z. D.; Sampath Kumar, A.; Hetzel, S.; Wittler, L.; Klages, S.; Timmermann, B.; Mukherji, S.; Meissner, A.: Epigenetic regulator function through mouse gastrulation. Nature 584 (7819), pp. 102 - 108 (2020)

Chua, R. L.; Lukassen, S.; Trump, S.; Hennig, B. P.; Wendisch, D.; Pott, F.; Debnath, O.; Thürmann, L.; Kurth, F.; Völker, M. T. et al.; Kazmierski, J.; Timmermann, B.; Twardziok, S.; Schneider, S.; Machleidt, F.; Müller-Redetzky, H.; Maier, M.; Krannich, A.; Schmidt, S.; Balzer, F.; Liebig, J.; Loske, J.; Suttorp, N.; Eils, J.; Ishaque, N.; Liebert, U. G.; von Kalle, C.; Hocke, A.; Witzenrath, M.; Goffinet, C.; Drosten, C.; Laudi, S.; Lehmann, I.; Conrad, C.; Sander, L.-E.; Eils, R.: COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. Nature Biotechnology 38 (8), pp. 970 - 979 (2020)

Xiao, Y.; Clima, R.; Busch, J.; Rabien, A.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Attimonelli, M.; Jung, K.; Meierhofer, D.: Decreased mitochondrial DNA content drives OXPHOS dysregulation in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research 80 (18), pp. 3830 - 3840 (2020)

Herdt, O.; Reich, S.; Medenbach, J.; Timmermann, B.; Olofsson, D.; Preußner, M.; Heyd, F.: The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation. RNA Biology 17 (6), pp. 843 - 856 (2020)

Haltenhof, T.; Kotte, A.; De Bortoli, F.; Schiefer, S.; Meinke, S.; Emmerichs, A.-K.; Petermann, K. K.; Timmermann, B.; Imhof, P.; Franz, A. et al.; Loll, B.; Wahl, M. C.; Preußner, M.; Heyd , F.: A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Molecular Cell 78 (1), pp. 57 - 69 (2020)

Bratovič, M.; Fonfara, I.; Chylinski, K.; Gálvez, E. J. C.; Sullivan, T. J.; Boerno, S.; Timmermann, B.; Boettcher, M.; Charpentier, E.: Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches. Nature Chemical Biology 16 (5), pp. 587 - 595 (2020)

Kupke, S. Y.; Ly, L.-H.; Börno, S. T.; Ruff, A.; Timmermann, B.; Vingron, M.; Haas, S.: Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses 12 (1), 71 (2020)

Fattahi, Z.; Beheshtian, M.; Mohseni, M.; Poustchi, H.; Sellars, E.; Nezhadi, S. H.; Amini, A.; Arzhangi, S.; Jalalvand, K.; Jamali, P. et al.; Mohammadi, Z.; Davarnia, B.; Nikuei, P.; Oladnabi, M.; Mohammadzadeh, A.; Zohrehvand, E.; Nejatizadeh, A.; Shekari, M.; Bagherzadeh, M.; Shamsi‐Gooshki, E.; Börno, S.; Timmermann, B.; Haghdoost, A.; Najafipour, R.; Khorram Khorshid, H. R.; Kahrizi, K.; Malekzadeh, R.; Akbari, M. R.; Najmabadi, H.: Iranome: A catalogue of genomic variations in the Iranian population. Human Mutation 40 (11), pp. 1968 - 1984 (2019)

Alahmad, A.; Paffrath, V.; Clima, R.; Busch, J. F.; Rabien, A.; Kilic, E.; Villegas, S.; Timmermann, B.; Attimonelli, M.; Jung, K. et al.; Meierhofer, D.: Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation. Cancers 11 (9), 1298 (2019)

Segal, J.; Mülleder, M.; Krüger, A.; Adler, T.; Scholze-Wittler, M.; Becker, L.; Calzada-Wack, J.; Garrett, L.; Hölter, S. M.; Rathkolb, B. et al.; Rozman, J.; Racz, I.; Fischer, R.; Busch, D. H.; Neff, F.; Klingenspor, M.; Klopstock, T.; Grüning, N.-M.; Michel, S.; Lukaszewska-McGreal, B.; Voigt, I.; Hartmann, L.; Timmermann, B.; Lehrach, H.; Wolf, E.; Wurst, W.; Gailus-Durner, V.; Fuchs, H.; de Angelis, M. H.; Schrewe, H.; Yuneva, M.; Ralser, M.: Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase (TPI) deficiency. Journal of Inherited Metabolic Disease 22 (5), pp. 839 - 849 (2019)

Bose, D.; Neumann, A.; Timmermann, B.; Meinke, S.; Heyd, F.: Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation. Molecular and Cellular Biology (Washington, DC) 39 (16), e00035-19 (2019)

Despang, A.; Schöpflin, R.; Franke, M.; Ali, S.; Jerković, I.; Paliou, C.; Chan, W.-L.; Timmermann, B.; Wittler, L.; Vingron, M. et al.; Mundlos, S.; Ibrahim, D. M.: Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture. Nature Genetics 51 (8), pp. 1263 - 1271 (2019)

Hu, H.; Kahrizi, K.; Musante, L.; Fattahi, Z.; Herwig, R.; Hosseini, M.; Oppitz, C.; Abedini, S. S.; Suckow, V.; Farzaneh, L. et al.; Beheshtian, M.; Lipkowitz, B.; Akhtarkhavari, T.; Mehvari, S.; Otto, S.; Mohseni, M.; Arzhangi, S.; Jamali, P.; Mojahedi, F.; Taghdiri, M.; Papari, E.; Soltani Banavandi, M. J.; Akbari, S.; Tonekaboni, S. H.; Dehghani, H.; Ebrahimpou, M. R.; Bader, I.; Davarnia, B.; Cohen, M.; Khodaei, H.; Albrecht, B.; Azimi, S.; Zirn, B.; Bastami, M.; Wieczorek, D.; Bahrami, G.; Keleman, K.; Vahid, L. N.; Timmermann, B.; Pourfatemi, F.; Jankhah, A.; Chen, W.; Nikuei, P.; Kalscheuer, V. M.; Oladnabi, M.; Wienker, T. F.; Ropers, H.-H.; Najmabadi, H.: Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 24 (7), pp. 1027 - 1039 (2019)