Publications of T. Mielke

Liu, C.; Young, A. L.; Starling-Windhof, A.; Bracher, A.; Saschenbrecker, S.; Rao, B. V.; Rao, K. V.; Berninghausen, O.; Mielke, T.; Hartl, F. U. et al.; Beckmann, R.; Hayer-Hartl, M.: Coupled chaperone action in folding and assembly of hexadecameric Rubisco. Nature 463 (7278), pp. 197 - 202 (2010)

Becker, T.; Bhushan, S.; Jarasch, A.; Armache, J.-P.; Soledad, S.; Jossinet, F.; Gumbart, J.; Mielke, T.; Berninghausen, O.; Schulten, K. et al.; Westhof, E.; Gilmore, R.; Mandon, E. C.; Beckmann, R.: Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science 326 (5958), pp. 1369 - 1373 (2009)

Jan-Christian Schuette, J.-C.; Murphy, F. V.; Kelley, A. C.; Weir, J. R.; Giesebrecht, J.; Connell, S. R.; Loerke, J.; Mielke, T.; Zhang, W.; Penczek, P. A. et al.; Ramakrishnan, V.; Spahn, C. M. T.: GTPase activation of elongation factor EF-Tu by the ribosome during decoding. The EMBO Journal 28 (6), pp. 755 - 765 (2009)

Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)

Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)

Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)

Chen, J. Z.; Sachse, C.; Xu, C.; Mielke, T.; Spahn, C. M. T.; Grigorieff, N.: A dose-rate effect in single-particle electron microscopy. Journal of Structural Biology 161 (1), pp. 92 - 100 (2008)

Kuhn, C.-D.; Geiger, S. R.; Baumli, S.; Gartmann, M.; Gerber, J.; Jennebach, S.; Mielke, T.; Tschochner, H.; Beckmann, R.; Cramer, P.: Functional architecture of RNA polymerase I. Cell 131 (7), pp. 1260 - 1272 (2007)

Connell, S. R.; Takemoto, C.; Wilson, D. N.; Wang, H.; Murayama, K.; Terada, T.; Shirouzu, M.; Rost, M.; Schüler, M.; Giesebrecht, J. et al.; Dabrowski, M.; Mielke, T.; Fucini, P.; Yokoyama, S.; Spahn, C. M. T.: Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Molecular Cell 25 (5), pp. 751 - 764 (2007)

Schüler, M.; Connell, S. R.; Lescoute, A.; Giesebrecht, J.; Dabrowski, M.; Schroeer, B.; Mielke, T.; Penczek, P. A.; Westhof, E.; Spahn, C. M. T.: Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nature Structural & Molecular Biology 13 (12), pp. 1092 - 1096 (2006)

Halic, M.; Blau, M.; Becker, T.; Mielke, T.; Pool, M. R.; Wild, K.; Sinning, I.; Beckmann, R.: Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature 444 (7118), pp. 507 - 511 (2006)

Andersen, C. B. F.; Becker, T.; Blau, M.; Anand, M.; Halic, M.; Balar, B.; Mielke, T.; Boesen, T.; Pedersen, J. S.; Spahn, C. M. T. et al.; Kinzy, T. G.; Andersen, G. R.; Beckmann, R.: Structure of eEF3 and the mechanism of transfer RNA release from the E-site. Nature 443 (7112), pp. 663 - 668 (2006)

Halic, M.; Gartmann, M.; Schlenker, O.; Mielke, T.; Pool, M. R.; Sinning, I.; Beckmann, R.: Signal recognition particle receptor exposes the ribosomal translocon binding site. Science 312 (5774), pp. 745 - 747 (2006)

Harnett, D.; Ambrozkiewicz, M. C.; Zinnall, U.; Rusanova, A.; Borisova, E.; Dannenberg, R.; Imami, K.; Münster-Wandowski,, A.; Fauler, B.; Mielke, T. et al.; Selbach, M.; Landthaler, M.; Spahn, C. M. T.; Tarabykin, V.; Ohler, U.; Kraushar, M.: A critical period of translational control during brain development at codon resolution. (2022)

van der Weijden, V. A.; Stötzel, M.; Fauler, B.; Iyer, D.; Shahraz, M.; Meierhofer, D.; Rulands, S.; Alexandrov, T.; Mielke, T.; Bulut-Karslioglu, A.: Metabolic enhancement of mammalian developmental pausing. (2022)