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Journal Article (22)

  1. 1.
    Journal Article
    Ratje, A. H.; Loerke, J.; Mikolajka, A.; Brunner, M.; Hildebrand, P. W.; Starosta, A. L.; Donhofer, A.; Connell, S. R.; Fucini, P.; Mielke, T. et al.; Whitford, P. C.; Onuchic, J. N.; Yu, Y.; Sanbonmatsu, K. Y.; Hartmann, R. K.; Penczek, P. A.; Wilson, D. N.; Spahn, C. M.: Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468 (7324), pp. 713 - 716 (2010)
  2. 2.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  3. 3.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  4. 4.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  5. 5.
    Journal Article
    Connell, S. R.; Takemoto, C.; Wilson, D. N.; Wang, H.; Murayama, K.; Terada, T.; Shirouzu, M.; Rost, M.; Schüler, M.; Giesebrecht, J. et al.; Dabrowski, M.; Mielke, T.; Fucini, P.; Yokoyama, S.; Spahn, C. M. T.: Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Molecular Cell 25 (5), pp. 751 - 764 (2007)
  6. 6.
    Journal Article
    Schluenzen, F.; Takemoto, C.; Wilson, D. N.; Kaminishi, T.; Harms, J. M. ..; Hanawa-Suetsugu, K.; Szaflarski, W.; Kawazoe, M.; Shirouzu, M.; Nierhaus, K. et al.; Yokoyama, S.; Fucini, P.: The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nature Structural & Molecular Biology 13, pp. 871 - 878 (2006)
  7. 7.
    Journal Article
    Wilson, D. N.; Harms, J. M.; Nierhaus, K. H.; Schlünzen, F.; Fucini, P.: Species-specific antibiotic-ribosome interactions: implications for drug development. Biological Chemistry Hoppe-Seyler (Berlin) 386 (12), pp. 1239 - 1252 (2005)
  8. 8.
    Journal Article
    Ilag, L. L.; Videler, H.; McKay, A. R.; Sobott, F.; Fucini, P.; Nierhaus, K. H.; Robinson, C. V.: Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria. Proceedings of the National Academy of Sciences of the United States of America (Washington, DC) 102 (23), pp. 8192 - 8197 (2005)
  9. 9.
    Journal Article
    Giavalisco, P.; Wilson, D.; Kreitler, T.; Lehrach, H.; Klose, J.; Gobom, J.; Fucini, P.: High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome. Plant Molecular Biology 57 (4), pp. 577 - 591 (2005)
  10. 10.
    Journal Article
    Mirgorodskaya, E.; Braeuer, C.; Fucini, P.; Lehrach, H.; Gobom, J.: Nanoflow liquid chromatography coupled to matrix-assisted laser desorption/ionization mass spectrometry: Sample preparation, data analysis, and application to the analysis of complex peptide mixtures. PROTEOMICS 5 (2), pp. 399 - 408 (2005)
  11. 11.
    Journal Article
    Mirgorodskaya, E.; Braeuer, C.; Fucini, P.; Lehrach, H.; Gobom, J.: Nanoflow liquid chromatography coupled to matrix-assisted laser desorption/ionization mass spectrometry: Sample preparation, data analysis, and application to the analysis of complex peptide mixtures. PROTEOMICS 5 (2), pp. 399 - 408 (2005)
  12. 12.
    Journal Article
    Schlünzen, F.; Pyetan, E.; Fucini, P.; Yonath, A.; Harms, J. M.: Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Molecular Microbiology 54 (5), pp. 1287 - 1294 (2004)
  13. 13.
    Journal Article
    Christodoulou, J.; Larsson, G.; Fucini, P.; Connell, S. R.; Pertinhez, T. A.; Hanson, C. L.; Redfield, C.; Nierhaus, K. H.; Robinson, C. V.; Schleucher, J. et al.; Dobson, C. M.: Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes. Proceedings of the National Academy of Sciences 101 (30), pp. 10949 - 10954 (2004)
  14. 14.
    Journal Article
    Gilbert, R. J. C.; Fucini, P.; Connell, S.; Fuller, S. D.; Nierhaus, K. H.; Robinson, C. V.; Dobson, C. M.; Stuart, D. I.: Three-dimensional structures of translating ribosomes by Cryo-EM. Molecular Cell 14 (1), pp. 57 - 66 (2004)
  15. 15.
    Journal Article
    Harms, J. M.; Schlünzen, F.; Fucini, P.; Bartels, H.; Yonath, A.: Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. BMC Biology 2, p. 4 - 4 (2004)
  16. 16.
    Journal Article
    Dinos, G.; Wilson, D. N.; Teraoka, Y.; Szaflarski, W.; Fucini, P.; Kalpaxis, D.; Nierhaus, K. H.: Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding. Molecular Cell 13 (1), pp. 113 - 124 (2004)
  17. 17.
    Journal Article
    Sharma, M. R.; Barat, C.; Wilson, D. N.; Booth, T. M.; Hori-Takemoto, C.; Yokoyama, S.; Fucini, P.; Agrawal, R. K.: ERA protein binds in a functionally important region of the 30S ribosomal subunit. Part 2 Suppl. S, pp. 316A - 317A (2004)
  18. 18.
    Journal Article
    Bashan, A.; Zarivach, R.; Schluenzen, F.; Agmon, I.; Harms, J.; Auerbach, T.; Baram, D.; Berisio, R.; Bartels, H.; Hansen, H. A. S. et al.; Fucini, P.; Wilson, D.; Peretz, M.; Kessler, M.; Yonath, A.: Ribosomal crystallography: peptide bond formation and its inhibition. Biopolymers 70 (1), pp. 19 - 41 (2003)
  19. 19.
    Journal Article
    Berisio, R.; Harms, J.; Schluenzen, F.; Zarivach, R.; Hansen, H. A. S.; Fucini, P.; Yonath, A.: Structural insight into the antibiotic action of telithromycin against resistant mutants (vol 185, pg 4276, 2003). Journal of Bacteriology 185 (14), pp. 4276 - 4279 (2003)
  20. 20.
    Journal Article
    Berisio, R.; Harms, J.; Schluenzen, F.; Zarivach, R.; Hansen, H. A. S.; Fucini, P.; Yonath, A.: Structural insight into the antibiotic action of telithromycin against resistant mutants. Journal of Bacteriology 185 (14), pp. 4276 - 4279 (2003)
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