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Journal Article (34)

  1. 1.
    Journal Article
    Bhushan, S.; Hoffmann, T.; Seidelt, B.; Frauenfeld, J.; Mielke, T.; Berninghausen, O.; Wilson, D. N.; Beckmann, R.: SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center. PLoS Biology 9 (1), p. e1000581 (2011)
  2. 2.
    Journal Article
    Ratje, A. H.; Loerke, J.; Mikolajka, A.; Brunner, M.; Hildebrand, P. W.; Starosta, A. L.; Donhofer, A.; Connell, S. R.; Fucini, P.; Mielke, T. et al.; Whitford, P. C.; Onuchic, J. N.; Yu, Y.; Sanbonmatsu, K. Y.; Hartmann, R. K.; Penczek, P. A.; Wilson, D. N.; Spahn, C. M.: Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468 (7324), pp. 713 - 716 (2010)
  3. 3.
    Journal Article
    Armache, J. P.; Jarasch, A.; Anger, A. M.; Villa, E.; Becker, T.; Bhushan, S.; Jossinet, F.; Habeck, M.; Dindar, G.; Franckenberg, S. et al.; Marquez, V.; Mielke, T.; Thomm, M.; Berninghausen, O.; Beatrix, B.; Soding, J.; Westhof, E.; Wilson, D. N.; Beckmann, R.: Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Preceedings of the National Academy of Sciences USA 107 (46), pp. 19748 - 19753 (2010)
  4. 4.
    Journal Article
    Armache, J. P.; Jarasch, A.; Anger, A. M.; Villa, E.; Becker, T.; Bhushan, S.; Jossinet, F.; Habeck, M.; Dindar, G.; Franckenberg, S. et al.; Marquez, V.; Mielke, T.; Thomm, M.; Berninghausen, O.; Beatrix, B.; Soding, J.; Westhof, E.; Wilson, D. N.; Beckmann, R.: Localization of eukaryote-specific ribosomal proteins in a 5.5-A cryo-EM map of the 80S eukaryotic ribosome. Proceedings of the National Academy of Sciences USA 107 (46), pp. 19754 - 19759 (2010)
  5. 5.
    Journal Article
    Bhushan, S.; Meyer, H.; Starosta, A. L.; Becker, T.; Mielke, T.; Berninghausen, O.; Sattler, M.; Wilson, D. N.; Beckmann, R.: Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide. (2010)
  6. 6.
    Journal Article
    Bhushan, S.; Gartmann, M.; Halic, M.; Armache, J. P.; Jarasch, A.; Mielke, T.; Berninghausen, O.; Wilson, D. N.; Beckmann, R.: alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel. Nature Structural & Molecular Biology 17 (3), pp. 313 - 317 (2010)
  7. 7.
    Journal Article
    Wilson, D. N.; Gupta, R.; Mikolajka, A.; Nierhaus, K. H.: Ribosomal proteins: role in ribosomal functions. Encyclopedia of Life Sciences 2009, p. 10 - 10 (2009)
  8. 8.
    Journal Article
    Wilson, D. N.; Starosta, A. L.; Yamamoto, H.; Nierhaus, K. H.: Inhibitors of the elongation cycle of protein synthesis. Encyclopedia of Life Sciences 2009, p. 13 - 13 (2009)
  9. 9.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  10. 10.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  11. 11.
    Journal Article
    Connell, S. R.; Topf, M.; Qin, Y.; Wilson, D. N.; Mielke, T.; Fucini, P.; Nierhaus, K. H.; Spahn, C. M. T.: A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology 15 (9), pp. 910 - 915 (2008)
  12. 12.
    Journal Article
    Szaflarski, W.; Vesper, O.; Teraoka, Y.; Plitta, B.; Wilson, D. N.; Nierhaus, K. H.: New features of the ribosome and ribosomal inhibitors: non-enzymatic recycling, misreading and back-translocation. Journal of Molecular Biology 380 (1), pp. 193 - 205 (2008)
  13. 13.
    Journal Article
    Di Giacco, V.; Márquez, V.; Yan Qin, Y.; Pech, M.; Triana-Alonso, F. J.; Wilson, D. N.; Nierhaus, K. H.: Shine-Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG. Proceedings of the National Academy of Sciences of the United States of America 105 (31), pp. 10715 - 10720 (2008)
  14. 14.
    Journal Article
    Wilson, D. N.; Nierhaus, K. H.: The oxazolidinone class of drugs find their orientation on the ribosome. Molecular Cell 26 (4), pp. 460 - 462 (2007)
  15. 15.
    Journal Article
    Wilson, D. N.; Nierhaus, K. H.: The weird and wonderful world of bacterial ribosome regulation. Critical Reviews in Biochemistry and Molecular Biology (Boca Raton, FL) 42 (3), pp. 187 - 219 (2007)
  16. 16.
    Journal Article
    Connell, S. R.; Takemoto, C.; Wilson, D. N.; Wang, H.; Murayama, K.; Terada, T.; Shirouzu, M.; Rost, M.; Schüler, M.; Giesebrecht, J. et al.; Dabrowski, M.; Mielke, T.; Fucini, P.; Yokoyama, S.; Spahn, C. M. T.: Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Molecular Cell 25 (5), pp. 751 - 764 (2007)
  17. 17.
    Journal Article
    Wilson, D. N.; Nierhaus, K.: The E-site story: the importance of maintaining two tRNAs on the ribosome during protein synthesis. Cellular and Molecular Life Sciences 63 (23), pp. 2725 - 2737 (2006)
  18. 18.
    Journal Article
    Qin, Y.; Polacek, N.; Vesper, O.; Staub, E.; Einfeldt, E.; Wilson, D. N.; Nierhaus, K.: The Highly Conserved LepA Is a Ribosomal Elongation Factor that Back-Translocates the Ribosome. Cell 127 (4), pp. 721 - 733 (2006)
  19. 19.
    Journal Article
    Seo, H.-S.; Abedin, S.; Kamp, D.; Wilson, D. N.; Nierhaus, K.; Cooperman, B. S.: EF-G-dependent GTPase on the ribosome: Conformational change and fusidic acid inhibition. Biochemistry 45 (8), pp. 2504 - 2514 (2006)
  20. 20.
    Journal Article
    Wilson, D. N.; Harms, J. M.; Nierhaus, K. H.; Schlünzen, F.; Fucini, P.: Species-specific antibiotic-ribosome interactions: implications for drug development. Biological Chemistry Hoppe-Seyler (Berlin) 386 (12), pp. 1239 - 1252 (2005)
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