Publications of R. Herwig

Schütte, M.; Risch, T.; Abdavi Azar, N.; Boehnke, K.; Schumacher, D.; Keil, M.; Yildiriman, R.; Jandrasits, C.; Borodina, T.; Amstislavskiy, V. et al.; Worth, C. L.; Schweiger, C.; Liebs, S.; Lange, M.; Warnatz, H. J.; Butcher, L. M.; Barrett, J. E.; Sultan, M.; Wierling, C.; Golob-Schwarzl, N.; Lax, S.; Uranitsch, S.; Becker, M.; Welte, Y.; Regan, J. L.; Silvestrov, M.; Kehler, I.; Fusi, A.; Kessler, T.; Herwig, R.; Landegren, U.; Wienke, D.; Nilsson, M.; Velasco, J. A.; Garin-Chesa, P.; Reinhard, C.; Beck, S.; Schafer, R.; Regenbrecht, C. R.; Henderson, D.; Lange, B.; Haybaeck, J.; Keilholz, U.; Hoffmann, J.; Lehrach, H.; Yaspo, M. L.: Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nature Communications 8, 8:14262 (2017)

Herwig, R.; Hardt, C.; Lienhard, M.; Kamburov, A.: Analyzing and interpreting genome data at the network level with ConsensusPathDB. Nature Protocols 11 (10), pp. 1889 - 1907 (2016)

Herwig, R.; Gmuender, H.; Corvi, R.; Bloch, K. M.; Brandenburg, A.; Castell, J.; Ceelen, L.; Chesne, C.; Doktorova, T. Y.; Jennen, D. et al.; Jennings, P.; Limonciel, A.; Lock, E. A.; McMorrow, T.; Phrakonkham, P.; Radford, R.; Slattery, C.; Stierum, R.; Vilardell, M.; Wittenberger, T.; Yildirimman, R.; Ryan, M.; Rogiers, V.; Kleinjans, J.: Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective. Archives of Toxikology 90 (9), pp. 2215 - 2229 (2016)

Broecker, F.; Hardt, C.; Herwig, R.; Timmermann, B.; Kerick, M.; Wunderlich, A.; Schweiger, M. R.; Borsig, L.; Heikenwalder, M.; Lehrach, H. et al.; Moelling, K.: Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line. The FEBS Journal 283 (9), pp. 1669 - 1688 (2016)

Hardt, C.; Beber, M. E.; Rasche, A.; Kamburov, A.; Hebels, D. G.; Kleinjans, J. C.; Herwig, R.: ToxDB: pathway-level interpretation of drug-treatment data. Database (Oxford) 2016, baw052 (2016)

Sudmant, P. H.; Rausch, T.; Gardner, E. J.; Handsaker, R. E.; Abyzov, A.; Huddleston, J.; The 1000 Genomes Project Consortium; Timmermann, B.; Herwig, R.; Lehrach, H.: An integrated map of structural variation in 2,504 human genomes. Nature 526 (7571), pp. 75 - 81 (2015)

The 1000 Genome Project Consortium; Lehrach, H.; Amstislavskiy, V.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.; Herwig, R.: A global reference for human genetic variation. Nature 526 (7571), pp. 68 - 74 (2015)

Hendrickx, D. M.; Aerts, H. J. W. L.; Caiment, F.; Clark, D.; Ebbels, T. M. D.; Evelo, C. T.; Gmuender, H.; Hebels, D. G. A. J.; Herwig, R.; Hescheler, J. et al.; Jennen, D. G. J.; Jetten, M. J. A.; Kanterakis, S.; Keun, H. C.; Matser, V.; Overington, J. P.; Pilicheva, E.; Sarkans, U.; Segura-Lepe, M. P.; Sotiriadou, I.; Wittenberger, T.; Wittwehr, C.; Zanzi, A.; Kleinjans, J. C. S.: diXa: a data infrastructure for chemical safety assessment. Bioinformatics 31 (9), pp. 1505 - 1507 (2015)

Herwig, R.: Computational modeling of drug response with applications to neuroscience. Dialogues in Clinical Neuroscience 16 (4), pp. 465 - 477 (2014)

Herwig, R.: Computational modelling of drug response with applications to neuroscience. Dialogues in Clinical Neuroscience 16 (4), pp. 465 - 477 (2014)

Reiner, G.; Dreher, F.; Drungowski, M.; Hoeltig, D.; Bertsch, N.; Selke, M.; Willems, H.; Gerlach, G. F.; Probst, I.; Tuemmler, B. et al.; Waldmann, K.-H.; Herwig, R.: Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine. Mammalian Genome 25 (11-12), pp. 600 - 617 (2014)

Hülsmann, H. J.; Rolff, J.; Bender, C.; Jarahian, M.; Korf, U.; Herwig, R.; Fröhlich, H.; Thomas, M.; Merk, J.; Fichtner, I. et al.; Sültmann, H.; Kuner, R.: Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib. Lung Cancer 86 (2), pp. 151 - 157 (2014)

Willems, T.; Gymrek, M.; Highnam, G.; The 1000 Genomes Project, C.; Herwig, R.; Lehrach, H.; Sudbrak, R.; Timmermann, B.; Mittelman, D.; Erlich, Y.: The landscape of human STR variation. Genome Research 24 (11), pp. 1894 - 1904 (2014)

Rasche, A.; Lienhard, M.; Yaspo, M.-L.; Lehrach, H.; Herwig, R.: ARH-seq: identification of differential splicing in RNA-seq data. Nucleic Acids Research (London) 42 (14), e110 (2014)

Colonna, V.; Ayub, Q.; Chen, Y.; Pagani, L.; Luisi, P.; Pybus, M.; Garrison, E.; Xue, Y.; Tyler-Smith, C.; 1000 Genomes Project, C. et al.; Sudbrak, R.; Albrecht, M.; Amstislavskiy, V.; Borodina, T. A.; Dahl, A.; Davydov, A.; Herwig, R.; Marquardt, P.; Mertes, F.; Nietfeld, W.; Parkhomchuk, D.; Soldatov, A. V.; Timmermann, B.; Tolzmann, M.; Lehrach, H.; Yaspo, M. L.: Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014)

Delaneau, O.; Marchini, J.; 1000 Genomes Project, C.; Lehrach, H.; Sudbrak, R.; Amstislavskiy, V. S.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B. et al.; Yaspo, M. L.; Herwig, R.: Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel. Nature Communications 5, 5:3934 (2014)

Doktorova, T. Y.; Yildirimman, R.; Ceelen, L.; Vilardell, M.; Vanhaecke, T.; Vinken, M.; Ates, G.; Heymans, A.; Gmuender, H.; Bort, R. et al.; Corvi, R.; Phrakonkham, P.; Li, R.; Mouchet, N.; Chesne, C.; van Delft, J.; Kleinjans, J.; Castell, J.; Herwig, R.; Rogiers, V.: Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model. Experimental and Clinical Sciences Journal (EXCLI Journal) 13, pp. 623 - 637 (2014)

Reiner, G.; Bertsch, N.; Hoeltig, D.; Selke, M.; Willems, H.; Gerlach, G. F.; Tuemmler, B.; Probst, I.; Herwig, R.; Drungowski, M. et al.; Waldmann, K. H.: Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine. Mammalian Genome 25 (3-4), pp. 180 - 191 (2014)

Hebels, D. G. A.; Jetten, M. J. A.; Aerts, H. J. W.; Herwig, R.; Theunissen, D. H. J.; Gaj, S.; van Delft, J. H.; Kleinjans, J. C. S.: Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity. Biomarkers in Medicine 8 (2), pp. 185 - 200 (2014)

Lienhard, M.; Grimm, C.; Morkel, M.; Herwig, R.; Chavez, L.: MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments. Bioinformatics 30 (2), pp. 284 - 286 (2014)