Publications of Ralf Herwig

Prasse, P.; Iversen, P.; Lienhard, M.; Thedinga, K.; Herwig, R.; Scheffer, T.: Pre-Training on In Vitro and Fine-Tuning on Patient-Derived Data Improves Deep Neural Networks for Anti-Cancer Drug-Sensitivity Prediction. Cancers / Molecular Diversity Preservation International (MDPI) 14 (16), 3950 (2022)

Kuhn, T.; Kaiser, K.; Lebek, S.; Altenhofen, D.; Knebel, B.; Herwig, R.; Rasche, A.; Pelligra, A.; Görigk, S.; Khuong, J. M.-A. et al.; Vogel, H.; Schürmann, A.; Blüher, M.; Chadt, A.; Al-Hasani, H.: Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene. Human Molecular Genetics 2022, ddac150 (2022)

Thedinga, K.; Herwig, R.: Gradient tree boosting and network propagation for the identification of pan-cancer survival networks. STAR Protocols 3 (2), 101353 (2022)

Thomalla, D.; Beckmann, L.; Grimm , C.; Oliverio, M.; Meder, L.; Herling, C. D.; Nieper, P.; Feldmann, T.; Merkel, O.; Lorsy, E. et al.; da Palma Guerreiro , A.; von Jan, J.; Kisis, I.; Wasserburger, E.; Claasen, J.; Faitschuk-Meyer, E.; Altmüller, J.; Nürnberg, P.; Yang, T.-P.; Lienhard, M.; Herwig, R.; Kreuzer, K.-A.; Pallasch, C. P.; Buettner, R.; Schäfer, S. C.; Hartley, J.; Abken, H.; Peifer, M.; Kashkar, H.; Knittel, G.; Eichhorst , B.; Ullrich, R. T.; Herling, M.; Reinhardt, H. C.; Hallek, M.; Schweiger, M. R.; Frenzel, L. P.: Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies. Blood (2022)

Nguyen, N.; Lienhard, M.; Herwig, R.; Kleinjans, J.; Jennen, D.: Epirubicin Alters DNA Methylation Profiles Related to Cardiotoxicity. Frontiers in Bioscience-Landmark 27 (6), 173 (2022)

Prasse , P.; Iversen , P.; Lienhard, M.; Thedinga, K.; Bauer, C.; Herwig, R.; Scheffer, T.: Matching anticancer compounds and tumor cell lines by neural networks with ranking loss. NAR: genomics and bioinformatics 4 (1), lqab128 (2022)

Thedinga, K.; Herwig, R.: A gradient tree boosting and network propagation derived pan-cancer survival network of the tumor microenvironment. iScience 25 (1), 103617 (2021)

Kamburov, A.; Herwig, R.: ConsensusPathDB 2022: molecular interactions update as a resource for network biology. Nucleic Acids Research, gkab1128 (2021)

Pacholewska, A.; Grimm, C.; Herling, C. D.; Lienhard, M.; Königs, A.; Timmermann, B.; Altmüller, J.; Mücke, O.; Reinhardt, H. C.; Plass, C. et al.; Herwig, R.; Hallek, M.; Schweiger, M. R.: Altered DNA Methylation Profiles in SF3B1 Mutated CLL Patients. International Journal of Molecular Sciences 22 (17), 9337 (2021)

Bauer, C.; Herwig, R.; Lienhard, M.; Prasse, P.; Scheffer, T.; Schuchhardt, J.: Large-scale literature mining to assess the relation between anti-cancer drugs and cancer types. Journal of Translational Medicine 19, 19:274 (2021)

Cichońska, A.; Ravikumar, B.; Allaway, R. J.; Wan, F.; Park, S.; Isayev, O.; Li, S.; Mason, M.; Lamb, A.; Tanoli, Z. et al.; Jeon, M.; Kim, S.; Popova, M.; Capuzzi, S.; Zeng, J.; Dang, K.; Koytiger, G.; Kang, J.; Wells, C. I.; Willson, T. M.; Lienhard, M.; Prasse, P.; Bachmann, I.; Ganzlin, J.; Barel, G.; Herwig, R.; Oprea, T. I.; Schlessinger, A.; Drewry, D. H.; Stolovitzky, G.; Wennerberg, K.; Guinney, J.; Aittokallio, T.: Crowdsourced mapping of unexplored target space of kinase inhibitors. Nature Communications 12, 3307 (2021)

Rehman, S. U.; Schallschmidt, T.; Rasche, A.; Knebel, B.; Stermann, T.; Altenhofen, D.; Herwig, R.; Schürmann, A.; Chadt, A.; Al‑Hasani, H.: Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development. Mammalian Genome 32 (3), pp. 153 - 172 (2021)

Farrall, A.; Lienhard, M.; Grimm, C.; Kuhl, H.; Sluka, S. H. M.; Caparros Rodriguez, M.; Forejt, J.; Timmermann, B.; Herwig, R.; Herrmann, B. G. et al.; Morkel, M.: PWD/Ph-encoded genetic variants modulate the cellular Wnt/β-Catenin response to suppress ApcMin-triggered intestinal tumor formation. Cancer research: an official organ of the American Association for Cancer Research 81 (1), pp. 38 - 49 (2021)

Klymenko , O.; Brecklinghaus, T.; Dille, M.; Springer, C.; de Wendt, C.; Altenhofen, D.; Binsch, C.; Knebel , B.; Scheller, J.; Hardt, C. et al.; Herwig, R.; Chadt, A.; Pfluger, P. T.; Al-Hasani, H.; Kabra, D. G.: Histone deacetylase 5 regulates Interleukin 6 secretion and insulin action in skeletal muscle. Molecular Metabolism 42, 101062 (2020)

Selevsek, N.; Caiment, F.; Nudischer, R.; Gmuender, H.; Agarkova, I.; Atkinson, F. L.; Bachmann, I.; Baier, V.; Barel, G.; Bauer, C. et al.; Boerno, S.; Bosc, N.; Clayton, O.; Cordes, H.; Deeb, S.; Gotta, S.; Guye, P.; Hersey, A.; Hunter, F. M. I.; Kunz, L.; Lewalle, A.; Lienhard, M.; Merken, J.; Minguet, J.; Oliveira, B.; Pluess, C.; Sarkans, U.; Schrooders, Y.; Schuchhardt, J.; Smit, I.; Thiel, C.; Timmermann, B.; Verheijen, M.; Wittenberger, T.; Wolski, W.; Zerck, A.; Heymans, S.; Kuepfer, L.; Roth, A.; Schlapbach, R.; Niederer, S.; Herwig, R.; Kleinjans, J.: Network integration and modelling of dynamic drug responses at multi-omics levels. Communications Biology 3, 573 (2020)

Barel, G.; Herwig, R.: NetCore: a network propagation approach using node coreness. Nucleic Acids Research 48 (17), e98 (2020)

Hu, H.; Kahrizi, K.; Musante, L.; Fattahi, Z.; Herwig, R.; Hosseini, M.; Oppitz, C.; Abedini, S. S.; Suckow, V.; Farzaneh, L. et al.; Beheshtian, M.; Lipkowitz, B.; Akhtarkhavari, T.; Mehvari, S.; Otto, S.; Mohseni, M.; Arzhangi, S.; Jamali, P.; Mojahedi, F.; Taghdiri, M.; Papari, E.; Soltani Banavandi, M. J.; Akbari, S.; Tonekaboni, S. H.; Dehghani, H.; Ebrahimpou, M. R.; Bader, I.; Davarnia, B.; Cohen, M.; Khodaei, H.; Albrecht, B.; Azimi, S.; Zirn, B.; Bastami, M.; Wieczorek, D.; Bahrami, G.; Keleman, K.; Vahid, L. N.; Timmermann, B.; Pourfatemi, F.; Jankhah, A.; Chen, W.; Nikuei, P.; Kalscheuer, V. M.; Oladnabi, M.; Wienker, T. F.; Ropers, H.-H.; Najmabadi, H.: Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 24 (7), pp. 1027 - 1039 (2019)

Weibl, P.; Herwig, R.: Superficial penile cancer treated with complete excision of the glans epithelium and coverage with a tissue sealant matrix (TachoSil®). Central European Journal of Urology 72 (2), 2:204–208 (2019)

Greilberger, J.; Greilberger, M.; Petek, T.; Stiegler, P.; Leber, B.; Reichl, H.; Kamel, A.; Herwig, R.: Effective Increase of Serum Vitamin D3 by IV Application of a Cholecalciferol-N-Acetyl-Galactosamine-Stabilized Dimer: a Clinical Murine Trial Study. Clinical Laboratory 65 (5), 181114 (2019)

Hoehe, M. R.; Herwig, R.; Mao , Q.; Peters , B. A.; Drmanac , R.; Church, G. M.; Huebsch, T.: Significant abundance of cis configurations of coding variants in diploid human genomes. Nucleic Acids Research (London) 47 (6), pp. 2981 - 2995 (2019)