Current Position
OWL Group leader
Max Planck Institute for Molecular Genetics
Cell Signaling Dynamics
Ihnestr. 63-73, Berlin 14195, Germany
www.molgen.mpg.de/cell-signaling-dynamics
Education
- 09/2002 - 07/2005: M.Sc. in Bioinformatics at Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.
- 09/1998 - 06/2002: B.Sc. in Biotechnology at College of Chemistry and Life Science, South-central University for Nationalities, Wuhan, China.
Dissertation
- Submitted in April 2008
- Mathematical modeling and kinetic analysis of cellular signaling pathways
Publications from time as IMPRS fellow
- Zhike Zi, Wolfram Liebermeister, Edda Klipp (2010)
A quantitative study of the Hog1 MAPK response to fluctuating osmotic stress in Saccharomyces cerevisiae.
PLoS One, 5 (3): e9522 - Zhike Zi, Yanan Zheng, Ann E Rundell, Edda Klipp (2008)
SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.
BMC Bioinformatics, 9: 342 - Zhike Zi, Edda Klipp (2007)
Steady state analyis of signal response in receptor trafficking networks.
Genome Inform.,18: 100-8 - Zhike Zi, Edda Klipp (2007)
Constraint-based modeling and kinetic analysis
of the smad dependent TGF-beta signaling pathway.
PLoS ONE, 2 (9): e936. - Zhike Zi, Edda Klipp (2007)
Cellular signaling is potentially regulated by
cell density in receptor trafficking networks.
FEBS Lett., 581 (24): 4589-95. - Zhike Zi, Edda Klipp (2006)
SBML-PET: a Systems Biology Markup Language-based parameter estimation tool.
Bioinformatics, 22: 2704-2705
Publications resulting from earlier appointments
- Zhike Zi, Zhirong Sun (2005)
Systems Biology: Systems-oriented biological research.
Systems Engineering----Theory & Practice, 25 (2): 47-55. - Zhike Zi, Kwang-Hyun Cho, Myong-Hee Sung, Xuefeng Xia, Jiashun Zheng and Zhirong Sun (2005)
In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.
FEBS Letters, 579 (5): 1101-8 - Zhike Zi, Zhirong Sun (2005)
Robustness Analysis of IFN-gamma induced JAK-STAT Signaling Pathway.
Journal of Computer Science & Technology, 20 (4): 491-5