Current Position

OWL Group leader

Max Planck Institute for Molecular Genetics

Cell Signaling Dynamics

Ihnestr. 63-73, Berlin 14195, Germany

www.molgen.mpg.de/cell-signaling-dynamics

Education

• 09/2002 - 07/2005: M.Sc. in Bioinformatics at Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.
• 09/1998 - 06/2002: B.Sc. in Biotechnology at College of Chemistry and Life Science, South-central University for Nationalities, Wuhan, China.

Dissertation

• Submitted in April 2008
• Mathematical modeling and kinetic analysis of cellular signaling pathways

Publications from time as IMPRS fellow

• Zhike Zi, Wolfram Liebermeister, Edda Klipp (2010)
  A quantitative study of the Hog1 MAPK response to fluctuating osmotic stress in Saccharomyces cerevisiae.
  PLoS One, 5 (3): e9522
• Zhike Zi, Yanan Zheng, Ann E Rundell, Edda Klipp (2008)
  SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.
  BMC Bioinformatics, 9: 342
• Zhike Zi, Edda Klipp (2007)
  Steady state analyis of signal response in receptor trafficking networks.
  Genome Inform.,18: 100-8
• Zhike Zi, Edda Klipp (2007)
  Constraint-based modeling and kinetic analysis
  of the smad dependent TGF-beta signaling pathway.
  PLoS ONE, 2 (9): e936.
• Zhike Zi, Edda Klipp (2007)
  Cellular signaling is potentially regulated by
  cell density in receptor trafficking networks.
  FEBS Lett., 581 (24): 4589-95.
• Zhike Zi, Edda Klipp (2006)
  SBML-PET: a Systems Biology Markup Language-based parameter estimation tool.
  Bioinformatics, 22: 2704-2705

Publications resulting from earlier appointments

• Zhike Zi, Zhirong Sun (2005)
  Systems Biology: Systems-oriented biological research.
  Systems Engineering----Theory & Practice, 25 (2): 47-55.
• Zhike Zi, Kwang-Hyun Cho, Myong-Hee Sung, Xuefeng Xia, Jiashun Zheng and Zhirong Sun (2005)
  In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.
  FEBS Letters, 579 (5): 1101-8
• Zhike Zi, Zhirong Sun (2005)
  Robustness Analysis of IFN-gamma induced JAK-STAT Signaling Pathway.
  Journal of Computer Science & Technology, 20 (4): 491-5