Current Position

OWL Group leader

Max Planck Institute for Molecular Genetics

Cell Signaling Dynamics

Ihnestr. 63-73, Berlin 14195, Germany


  • 09/2002 - 07/2005: M.Sc. in Bioinformatics at Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.
  • 09/1998 - 06/2002: B.Sc. in Biotechnology at College of Chemistry and Life Science, South-central University for Nationalities, Wuhan, China.


Publications from time as IMPRS fellow

  • Zhike Zi, Wolfram Liebermeister, Edda Klipp (2010)
    A quantitative study of the Hog1 MAPK response to fluctuating osmotic stress in Saccharomyces cerevisiae.
    PLoS One, 5 (3): e9522
  • Zhike Zi, Yanan Zheng, Ann E Rundell, Edda Klipp (2008)
    SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool.
    BMC Bioinformatics, 9: 342
  • Zhike Zi, Edda Klipp (2007)
    Steady state analyis of signal response in receptor trafficking networks.
    Genome Inform.,18: 100-8
  • Zhike Zi, Edda Klipp (2007)
    Constraint-based modeling and kinetic analysis
    of the smad dependent TGF-beta signaling pathway.
    PLoS ONE, 2 (9): e936.
  • Zhike Zi, Edda Klipp (2007)
    Cellular signaling is potentially regulated by
    cell density in receptor trafficking networks.
    FEBS Lett., 581 (24): 4589-95.
  • Zhike Zi, Edda Klipp (2006)
    SBML-PET: a Systems Biology Markup Language-based parameter estimation tool.
    Bioinformatics, 22: 2704-2705

Publications resulting from earlier appointments

  • Zhike Zi, Zhirong Sun (2005)
    Systems Biology: Systems-oriented biological research.
    Systems Engineering----Theory & Practice, 25 (2): 47-55.
  • Zhike Zi, Kwang-Hyun Cho, Myong-Hee Sung, Xuefeng Xia, Jiashun Zheng and Zhirong Sun (2005)
    In silico identification of the key components and steps in IFN-gamma induced JAK-STAT signaling pathway.
    FEBS Letters, 579 (5): 1101-8
  • Zhike Zi, Zhirong Sun (2005)
    Robustness Analysis of IFN-gamma induced JAK-STAT Signaling Pathway.
    Journal of Computer Science & Technology, 20 (4): 491-5
Go to Editor View