Current Position

Genome Institute of Singapore

60 Biopolis St, 138672 Singapore


  • 2006: Visiting student, University of Sheffield (UK)
  • 2007: B.Sc. in Bioinformatics, Freie Universität Berlin (Germany)
  • 2007 - 2012: PhD studies at the IMPRS-CBSC supervised by Prof. Dr. Martin Vingron

Work experience

  • 2006-2007: Tutor at Freie Universität Berlin
  • 2004-2007: Student assistant at the Charité
  • 2004: Internship at Max Delbrück Center for Molecular Medicine (MDC)
  • 2003: National Service (non-military option) at Charite Berlin, clinical cancer research


Scientific Interests

  • Comparative Genomics
  • Recurring motifs in non-coding DNA

Publications from time as IMPRS fellow

  • H Hu et al. (2015)
    X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.
    Mol Psychiatry, [epub ahead of print]
  • J Göke, YS Chan, J Yan, M Vingron, HH Ng (2013)
    Genome-wide kinase-chromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells.
    Mol Cell, 50 (6): 844-55
  • YS Chan, J Göke, X Lu, N Venkatesan, B Feng, IH Su, HH Ng (2012)
    A PRC2 dependent repressive role of PRDM14 in human embryonic stem cells and iPSC reprogramming.
    Stem Cells, 31 (4): 682-92
  • J Göke, MH Schulz, J Lasserre, M Vingron (2012)
    Estimation of pairwise sequence similarity of mammalian enhancers with word neighbourhood counts.
    Bioinformatics, 28 (5): 656-63
  • J Göke et al. (2011)
    Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development.
    PLoS Comput Biol., 7 (12): e1002304
  • PJ McMurdie, SF Behrens, JA Müller, J Göke et al. (2009)
    Localized plasticity in the streamlined genomes of vinyl chloride respiring Dehalococcoides.
    PLoS Genet. 5 (11): e1000714
  • K Kosta, I Sabroe, J Göke, RJ Nibbs, J Tsanakas, MK Whyte, MD Teare (2007)
    A Bayesian approach to copy-number-polymorphism analysis in nuclear pedigrees.
    Am J Hum Genet., 81 (4): 808-12
  • MD Teare, I Sabroe, J Goeke, M Whyte (2007)
    Family based association analysis of a copy number polymorphism in asthma families
    Genetic Epidemiology, 31 (5): 500
  • J Gellermann, J Göke, R Figiel, M Weihrauch, CH Cho, V Budach, R Felix, P Wust (2007)
    Simulation of different applicator positions for treatment of a presacral tumour
    Int J Hyperthermia, 23 (1): 37-47
  • Assembly and analysis of the genome of Dehalococcoides strain VS.
    Bachelor's thesis, Stanford University/ Freie Universität Berlin, 2007
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