Suchergebnisse

Sen, N.-E.; Canet-Pons, J.; Halbach, M. V.; Arsovic, A.; Pilatus, U.; Chae, W.-H.; Kaya, Z.-E.; Seidel, K.; Rollmann, E.; Mittelbronn, M. et al.; Meierhofer, D.; De Zeeuw, C. I.; Bosman, L. W. J.; Gispert, S.; Auburger, G.: Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation. Neurobiology of Disease 132, 104559 (2019)

Xiao, Y.; Meierhofer, D.: Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies. International Journal of Molecular Sciences 20 (15), E3672 (2019)

Berndt , N.; Eckstein, J.; Heucke, N.; Gajowski, R.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: Characterization of Lipid and Lipid Droplet Metabolism in Human HCC. Cells 8 (5), 512 (2019)

Hudert, C. A.; Selinski, S.; Rudolph, B.; Bläker, H.; Loddenkemper, C.; Thielhorn, R.; Berndt, N.; Golka, K.; Cadenas, C.; Reinders, J. et al.; Henning, S.; Bufler, P.; Jansen, P. L. M.; Holzhütter, H.; Meierhofer, D.; Hengstler, J. G.; Wiegand, S.: Genetic determinants of steatosis and fibrosis progression in paediatric non‐alcoholic fatty liver disease. Liver International 39 (3), S. 540 - 556 (2019)

Berndt, N.; Bulik, S.; Wallach, I.; Wünsch, T.; König, M.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology. Nature Communications 9 , 9:2386 (2018)

Baek, J. Y.; Geissner, A.; Rathwell, D. C. K.; Meierhofer, D.; Pereira, C. L.; Seeberger , P.: A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate. Chemical Science 9 (5), S. 1279 - 1288 (2018)

Kürschner, G.; Zhang, Q.; Clima, R.; Xiao , Y.; Busch, J. F.; Kilic, E.; Jung, K.; Berndt, N.; Bulik, S.; Holzhütter, H.-G. et al.; Gasparre, G.; Attimonelli, M.; Babu, M.; Meierhofer, D.: Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione. Oncotarget 2017, 8:105882-105904 (2017)

Corwin, T.; Woodsmith, J.; Apelt, F.; Fontaine, J.-F.; Meierhofer, D.; Helmuth, J.; Grossmann, A.; Andrade-Navarro, M. A.; Ballif, B. A.; Stelzl, U.: Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate. Cell Systems 5 (2), e4, S. 128 - 139 (2017)

Torres-Odio, S.; Key, J.; Hoepken, H.-H.; Canet-Pons, J.; Valek, L.; Roller, B.; Walter, M.; Morales-Gordo, B.; Meierhofer, D.; Harter, P. N. et al.; Mittelbronn, M.; Tegeder, I.; Gispert, S.; Auburger, G.: Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. Journal of Neuroinflammation 14 (1), 14:154 (2017)

Auburger, G.; Sen, N.-E.; Meierhofer, D.; Başak, A.-N.; Gitler, A. D.: Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2. Trends in Neurosciences 40 (8), S. 507 - 516 (2017)

Lorenz, C.; Lesimple, P.; Bukowiecki, R.; Zink, A.; Inak, G.; Mlody, B.; Singh, M.; Semtner, M.; Mah, N.; Auré, K. et al.; Leong, M.; Zabiegalov, O.; Lyras, E.-M.; Pfiffer, V.; Fauler, B.; Eichhorst, J.; Wiesner, B.; Huebner, N.; Priller, J.; Mielke, T.; Meierhofer, D.; Izsvák, Z.; Meier, J. C.; Bouillaud, F.; Adjaye, J.; Schuelke, M.; Wanker, E. E.; Lombès, A.; Prigione, A.: Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell 20 (5), e9, S. 659 - 674 (2017)

Twardziok, M.; Meierhofer, D.; Börno, S. T.; Timmermann, B.; Jäger, S.; Boral, S.; Eggert, A.; Delebinski, C. I.; Seifeert, G.: Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses. BMC Complementary and Alternative Medicine 2017, 17:237 (2017)

Medina, A. B.; Banaszczak, M.; Ni, Y.; Aretz, I.; Meierhofer, D.: ρ⁰ Cells Feature De-Ubiquitination of SLC Transporters and Increased Levels and Fluxes of Amino Acids. International Journal of Molecular Sciences 18, E879 (2017)

Seidel, G.; Meierhofer, D.; Şen, N.-E.; Guenther, A.; Krobitsch, S.; Auburger, G.: Quantitative Global Proteomics of Yeast PBP1 Deletion Mutants and Their Stress Responses Identifies Glucose Metabolism, Mitochondrial, and Stress Granule Changes. Journal of Proteome Research 16 (2), S. 504 - 515 (2017)

Telorac, J.; Prykhozhij, S.; Schöne, S.; Meierhofer, D.; Sauer, S.; Thomas-Chollier, M.; Meijsing, S. H.: Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements. Nucleic Acids Research (London) 44 (13), S. 6142 - 6156 (2016)

Vucicevic, D.; Gehre, M.; Dhamija, S.; Friis-Hansen, L.; Meierhofer, D.; Sauer, S.; Ørom, U. A.: The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation. Oncotarget 7 (23), S. 33934 - 33947 (2016)

Chung, H.-R.; Xu, C.; Fuchs, A.; Mund, A.; Lange, M.; Staege, H.; Schubert, T.; Bian, C.; Dunkel, I.; Eberharter, A. et al.; Regnard, C.; Klinker, H.; Meierhofer, D.; Cozzuto, L.; Winterpracht, A.; Di Croce, L.; Min, J.; Will, H.; Kinkley, S.: PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. eLife 5, 5:e10607 (2016)

Aretz, I.; Hardt, C.; Wittig, I.; Meierhofer, D.: An impaired respiratory electron chain triggers down-regulation of the energy metabolism and de-ubiquitination of solute carrier amino acid transporters. Molecular and Cellular Proteomics 15 (5), S. 1526 - 1538 (2016)

Meierhofer, D.; Halbach, M.; Şen, N. E.; Gispert, S.; Auburger, G.: Atxn2-Knock-Out mice show branched chain amino acids and fatty acids pathway alterations. Molecular and Cellular Proteomics 15 (5), S. 1728 - 1739 (2016)

Aretz, I.; Meierhofer, D.: Advantages and Pitfalls of Mass Spectrometry Based Metabolome Profiling in Systems Biology. International Journal of Molecular Sciences 17 (5), pii: E632 (2016)