Publikationen von Helene Kretzmer

Chteinberg, E.; Kolarova, J.; Vogt, J.; Macamo, A.; Bormann, F.; Kretzmer, H.; Speel, E. J.; van den Oord, J.; Schneider, C.; Stilgenbauer, S. et al.; Becker, J. C.; Winnepenninckx, V.; Biessen, E.; Zenke, M.; Kurz, A. K.; Siebert, R.; Zur Hausen , A.: The significance of PAX5 in Merkel cell carcinoma. The Journal of Pathology: an Official Journal of the Pathological Society of Great Britain and Ireland 266 (1), S. 81 - 94 (2025)

Glaser , S.; Fischer, A.; Martínez-Manjón, J. E.; López, C.; Kretzmer, H.; Burkhardt, B.; Hübschmann, D.; Hummel, M.; Klapper, W.; Kolarova, J. et al.; Kreuz, M.; Ott, G. e. a.: Subgrouping germinal center-derived B-cell lymphomas based on machine learning-deduced DNA methylation modules. Leukemia 39 (4), S. 967 - 971 (2025)

Brändl, B.; Steiger, M.; Kubelt, C.; Rohrandt, C.; Zhu, Z.; Evers, M.; Wang, G.; Schuldt, B.; Afflerbach, A.-K.; Wong, D. et al.; Lum, A.; Halldorsson, S.; Djirackor, L.; Leske, H.; Magadeeva, S.; Smicius, R.; Quedenau, C.; Schmidt, N. O.; Schüller, U.; Vik-Mo, E. O.; Proescholdt, M.; Riemenschneider, M. J.; Zadeh, G.; Ammerpohl, O.; Yip, S.; Synowitz, M.; van Bömmel, A.; Kretzmer, H.; Müller, F.-J.: Rapid brain tumor classification from sparse epigenomic data. Nature Medicine 31 (3), S. 840 - 848 (2025)

Glaser, S.; Kretzmer, H.; Kolassa, I. T.; Schlesner, M.; Fischer, A.; Fenske, I.; Siebert, R.; Ammerpohl , O.: Navigating Illumina DNA methylation data: biology versus technical artefacts. NAR: genomics and bioinformatics 6 (4), Article lqae181 (2024)

Stötzel, M.; Cheng, C.-Y.; Ilik, I. A.; Sampath Kumar, A.; Akbari-Omgba, P.; van der Weijden, V. A.; Zhang, Y.; Vingron, M.; Meissner, A.; Aktas, T. et al.; Kretzmer, H.; Bulut-Karslioglu, A.: TET activity safeguards pluripotency throughout embryonic dormancy. Nature Structural & Molecular Biology 31 (10), S. 1625 - 1639 (2024)

Fleischmann, L. S.; Nemes, K.; Glaser, S.; Kouroukli, A. G.; Boros , M.; Bens, S.; Dahlum, S.; Kretzmer, H.; Oyen, F.; Gerss, J. et al.; Hasselblatt, M.; Frühwald, M. C.; Siebert, R.: Constitutional mosaicism of pathogenic variants in SMARCB1 in a subset of patients with sporadic rhabdoid tumors. Neuro-Oncology: official journal of the World Federation of Neuro-Oncology, Article noae188 (2024)

Roessner, P. M.; Seufert, I.; Chapaprieta, V.; Jayabalan, R.; Briesch, H.; Massoni-Badosa, R.; Boskovic, P.; Benckendorff, J. ....; Kretzmer, H.; Naake, T. e. a.: T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia. Blood 144 (5), S. 510 - 524 (2024)

Bolondi, A.; Law, B. K.; Kretzmer, H.; Gassaloglu, S. I.; Buschow, R.; Riemenschneider, C.; Yang, D.; Walther, M.; Veenvliet, J. V.; Meissner, A. et al.; Smith, Z. D.; Chan, M. M.: Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids. Developmental Cell 59 (12), S. 1489 - 1505 (2024)

Sato, N. S.; Rosa , V. S.; Makhlouf, A.; Kretzmer, H.; Sampath Kumar, A.; Grosswendt, S.; Mattei, A. L.; Courbot, O.; Wolf, S.; Boulanger, J. et al.; Langevin, F.; Wiacek, M.; Karpinski, D.; Elosegui-Artola, A.; Meissner, A.; Zernicka-Goetz , M.; Shahbazi, M. N.: Basal delamination during mouse gastrulation primes pluripotent cells for differentiation. Developmental Cell 59 (10), S. 1252 - 1268 (2024)

Hauswedell , H.; Hetzel, S.; Gottlieb , S. G.; Kretzmer, H.; Meissner, A.; Reinert, K.: Lambda3: homology search for protein, nucleotide, and bisulfite-converted sequences. Bioinformatics 40 (3), Article btae097 (2024)

Zhou, W.; Fischer, A.; Ogwang, M. D.; Luo, W.; Kerchan, P.; Reynolds, S. J.; Tenge, C. N.; Were, P. A.; Kuremu, R. T.; Wekesa, W. N. et al.; Masalu, N.; Kawira, E.; Kinyera, T.; Otim, I.; Legason, I. D.; Nabalende, H.; Ayers, L. W.; Bhatia, K.; Goedert, J. J.; Gouveia, M. H.; Cole, N.; Hicks, B.; Jones, K.; Hummel, M.; Schlesner, M.; Chagaluka, G.; Mutalima, N.; Borgstein, E.; Liomba, G. N.; Kamiza, S.; Mkandawire, N.; Mitambo, C.; Molyneux, E. M.; Newton, R.; Glaser, S.; Kretzmer, H.; Manning, M.; Hutchinson, A.; Hsing, A. W.; Tettey, Y.; Adjei, A. A.; Chanock, S. J.; Siebert, R.; Yeager, M.; Prokunina-Olsson, L.; Machiela, M. J.; Mbulaiteye, S. M.: Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa. Nature Communications 14 (1), 8081 (2023)

Kouroukli, A. G.; Rajaram, N.; Bashtrykov, P.; Kretzmer, H.; Siebert, R.; Jeltsch, A.; Bens, S.: Targeting oncogenic TERT promoter variants by allele-specific epigenome editing. Clinical Epigenetics 15 (1), 183 (2023)

Sampath Kumar, A.; Tian, L.; Bolondi, A.; Aragonés Hernández, A.; Stickels, R.; Kretzmer, H.; Murray, E.; Wittler, L.; Walther, M.; Barakat, G. et al.; Haut, L.; Elkabetz, Y.; Macosko, E. Z.; Guignard, L.; Chen, F.; Meissner, A.: Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis. Nature Genetics 55 (7), S. 1176 - 1185 (2023)

Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 25 (4), S. 579 - 591 (2023)

Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S. D.; Braendl, B.; Gießelmann, P. et al.; Tornisiello, R.; Mohan Parsi, K.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.: T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. eLife 12, Article e83077 (2023)

Knisbacher, B. A.; Lin, Z.; Hahn, C. K.; Nadeu, F.; Duran-Ferrer, M.; Stevenson, K. E.; Tausch, E.; Delgado, J.; Barbera-Mourelle, A.; Taylor-Weiner, A. et al.; Bousquets-Muñoz, P.; Diaz-Navarro, A.; Dunford, A.; Anand, S.; Kretzmer, H.; Gutierrez-Abril, J.; López-Tamargo, S.; Fernandes, S. M.; Sun, C.; Sivina, M.; Rassenti, L. Z.; Schneider, C.; Li, S.; Parida, L.; Meissner, A.; Aguet , F.; Burger, J. A.; Wiestner, A.; Kipps, T. J.; Brown, J. R.; Hallek, M.; Stewart, C.; Neuberg, D. S.; Martín-Subero , J. I.; Puente, X. S.; Stilgenbauer, S.; Wu, C. J.; Campo, E.; Getz, G.: Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nature Genetics 54, S. 1664 - 1674 (2022)

Asimi, V.; Sampath Kumar, A.; Niskanen, H.; Riemenschneider, C.; Hetzel, S.; Naderi, J.; Fasching, N.; Popitsch, N.; Du, M.; Kretzmer, H. et al.; Smith, Z. D.; Weigert, R.; Walther, M.; Mamde, S.; Meierhofer, D.; Wittler, L.; Buschow, R.; Timmermann, B.; Cisse, I. I.; Ameres, S. L.; Meissner, A.; Hnisz, D.: Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 54 (8), S. 1238 - 1247 (2022)

Hetzel, S.; Mattei, A. L.; Kretzmer, H.; Qu, C.; Chen, X.; Fan, Y.; Wu, G.; Roberts, K. G.; Luger, S.; Litzow, M. et al.; Rowe, J.; Paietta, E.; Stock, W.; Mardis, E. R.; Wilson, R. K.; Downing, J. R.; Mullighan, C. G.; Meissner, A.: Acute lymphoblastic leukemia displays a distinct highly methylated genome. Nature Cancer 3 (6), S. 768 - 782 (2022)

Pour, M.; Sampath Kumar, A.; Farag, N.; Bolondi, A.; Kretzmer, H.; Walther, M.; Wittler, L.; Meissner, A.; Nachman, I.: Emergence and patterning dynamics of mouse-definitive endoderm. iScience 25 (1), 103556 (2022)

Biran, A.; Yin, S.; Kretzmer, H.; ten Hacken, E.; Parvin, S.; Lucas, F.; Uduman, M.; Gutierrez, C.; Dangle, N. ....; Meissner, A. et al.; Wu, C. J.: Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia. Cancer Research 81 (24), S. 6117 - 6130 (2021)