Nanocourse: Cancer Genomics

  • Start: Nov 14, 2022 10:00 AM c.t. (Local Time Germany)
  • End: Nov 15, 2022 05:00 PM
  • Speakers: Yaspo's research group
  • Location: Max Planck Institute for Molecular Genetics
  • Room: Seminar room 1
  • Host: Anne-Dominique Gindrat
  • Contact:
Nanocourse: Cancer Genomics
“ Portraits of a tumor: cancer cells and their microenvironment or building a new world in a tissue”

Nanocourses consist of lectures followed by the opportunity to gain hands-on experience.

Please register for this course by emailing


14th November 2022 – Session 1: Imaging of cancer tissues

10:00 – 10:45 Introduction to Cancer Genomics (Marie-Laure Yaspo) (SR4)

10:45 – 11:00 Coffee break

11:00 – 11:45 Lecture by Prof. Christian Conrad BIH. Charité: “Single cell sequencing and imaging” (SR4)

11:45 – 12:15 Time for discussion (SR4)

12:15 – 13:00 Lunch break

13:00 – 14:00 Introduction to Imaging mass cytometry (IMC), Image analysis (Anika Rettig) (SR1)

14:00 – 15:00 Visit to the lab and Hyperion instrument (Alexander Kovacsovics) (Yaspo's lab)

15:00 – 16:30 Hands on Hyperion data and image analysis, and open discussions (PC room)

15th November 2022 – Session 2: Molecular Analysis of cancer tissue

10:00 – 11:00 Lecture: Transcriptomics, eRNAs and gene regulation networks in cancer (Marie-Laure Yaspo, Begüm Özemek) (SR1)

11:00 – 12:30 Journal club (the group to pick 1-3 papers to discuss) (SR1)

  • L. Kuett et al. Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment. Nature Cancer PMID: 35121992

  • M. Schütte et al. Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nat Comms. PMID: 28186126

  • Karras et al. A cellular hierarchy in melanoma uncouples growth and metastasis. Nature. PMID: 36131018

12:30 – 13:30 Lunch break

13:30 – 14:30 Technologies to decipher gene regulation networks (ChiPseq, Cut&Run) (Ozan Otas) (SR1)

14:30 – 14:45 Coffee break

14:45 – 16:00 Data hands-on with ChipSeq and Cut&Run (Wanwan Ge) (PC room)

16:00 – 17:00 CROPseq technologies and functional networks (Mathurin Dorel) (SR1)

Before signing up for this nanocourse, please make sure that you can attend all the dates and write them in your calendar. If you do not show up or cancel at very short notice, other interested students will not be able to participate.

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