Nanocourse: Cancer Genomics
- Start: Nov 14, 2022 10:00 AM c.t. (Local Time Germany)
- End: Nov 15, 2022 05:00 PM
- Speakers: Yaspo's research group
- https://www.molgen.mpg.de/166100/Gene-Regulation-and-Systems-Biology-of-Cancer
- Location: Max Planck Institute for Molecular Genetics
- Room: Seminar room 1
- Host: Anne-Dominique Gindrat
- Contact: imprs-bac@molgen.mpg.de
Nanocourses consist of lectures followed by the opportunity to gain hands-on experience.
Please register for this course by emailing imprs-bac@molgen.mpg.de.
Schedule
14th November 2022 – Session 1: Imaging of cancer tissues
10:00 – 10:45 Introduction to Cancer Genomics (Marie-Laure Yaspo) (SR4)
10:45 – 11:00 Coffee break
11:00 – 11:45 Lecture by Prof. Christian Conrad BIH. Charité: “Single cell sequencing and imaging” (SR4)
11:45 – 12:15 Time for discussion (SR4)
12:15 – 13:00 Lunch break
13:00 – 14:00 Introduction to Imaging mass cytometry (IMC), Image analysis (Anika Rettig) (SR1)
14:00 – 15:00 Visit to the lab and Hyperion instrument (Alexander Kovacsovics) (Yaspo's lab)
15:00 – 16:30 Hands on Hyperion data and image analysis, and open discussions (PC room)
15th November 2022 – Session 2: Molecular Analysis of cancer tissue
10:00 – 11:00 Lecture: Transcriptomics, eRNAs and gene regulation networks in cancer (Marie-Laure Yaspo, Begüm Özemek) (SR1)
11:00 – 12:30 Journal club (the group to pick 1-3 papers to discuss) (SR1)
L. Kuett et al. Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment. Nature Cancer PMID: 35121992
M. Schütte et al. Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nat Comms. PMID: 28186126
Karras et al. A cellular hierarchy in melanoma uncouples growth and metastasis. Nature. PMID: 36131018
12:30 – 13:30 Lunch break
13:30 – 14:30 Technologies to decipher gene regulation networks (ChiPseq, Cut&Run) (Ozan Otas) (SR1)
14:30 – 14:45 Coffee break
14:45 – 16:00 Data hands-on with ChipSeq and Cut&Run (Wanwan Ge) (PC room)
16:00 – 17:00 CROPseq technologies and functional networks (Mathurin Dorel) (SR1)
Before signing up for this nanocourse, please make sure that you can attend all the dates and write them in your calendar. If you do not show up or cancel at very short notice, other interested students will not be able to participate.