Publications of Sebastiaan Meijsing

Kulik, M.; Bothe, M.; Kibar, G.; Fuchs , A.; Schöne, S.; Prekovic, S.; Mayayo Peralta, I.; Chung, H.-R.; Zwart, W.; Helsen, C. et al.; Claessens, F.; Meijsing, S.: Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites. Nucleic Acids Research (London) 49 (7), pp. 3856 - 3875 (2021)

Ramisch, A.; Heinrich, V.; Glaser, L. V.; Fuchs, A.; Yang, X.; Benner, P.; Schöpflin, R.; Li, N.; Kinkley, S.; Römer-Hillmann, A. et al.; Longinotto, J.; Heyne, S.; Czepukojc, B.; Kessler, S. M.; Kiemer, A. K.; Cadenas, C.; Arrigoni, L.; Gasparoni, N.; Manke, T.; Pap, T.; Pospisilik, A.; Hengstler, J.; Walter, J.; Meijsing, S.; Chung, H.-R.; Vingron, M.: CRUP: a comprehensive framework to predict condition-specific regulatory units. Genome Biology: Biology for the Post-Genomic Era 20 (1), 227 (2019)

Li, H.; Kaiser, T. K.; Borschiwer, M.; Bohnenberger, H.; Reichardt, S. D.; Luhder, F.; Walter, L.; Dressel, R.; Meijsing, S.; Reichardt, H. M.: Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft-versus-host disease. Journal of Steroid Biochemistry and Molecular Biology 195, 105485 (2019)

Malik, V.; Glaser, L. V.; Zimmer, D.; Velychko, S.; Weng, M.; Holzner, M.; Arend, M.; Chen, Y.; Srivastava, Y.; Veerapandian, V. et al.; Shah, Z.; Esteban, M. A.; Wang, H.; Chen, J.; Scholer, H. R.; Hutchins, A. P.; Meijsing, S. H.; Pott, S.; Jauch, R.: Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2. Nature Communications 10 (1), 3477 (2019)

Thormann, V.; Glaser, L. V.; Rothkegel, M. C.; Borschiwer, M.; Bothe, M.; Fuchs, A.; Meijsing, S. H.: Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements. Life Science Alliance 2 (2), e201800283 (2019)

Schöne, S.; Bothe, A. M.; Einfeldt, E.; Borschiwer, M.; Benner, P. F.; Vingron, M.; Thomas-Chollier, M.; Meijsing, S. H.: Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise. PLoS Genetics 14 (11), e1007793 (2018)

Tolkachov, A.; Fischer, C.; Ambrosi, T. H.; Bothe, A. M.; Han, C.-T.; Muenzner, M.; Mathia, S.; Salminen, M.; Seifert, G.; Thiele, M. et al.; Duda, G. N.; Meijsing, S.; Sauer, S.; Schulz, T. J.; Schupp, M.: Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone. Molecular and Cellular Biology (Washington, DC) 38 (12), e00599-17 (2018)

Thormann, V.; Rothkegel, M. C.; Schöpflin, R.; Glaser, L. V.; Djuric, P.; Li, N.; Chung, H.-R.; Schwahn, K.; Vingron, M.; Meijsing, S.: Genomic dissection of enhancers uncovers principles of combinatorial regulation and dynamic wiring of enhancer-promoter contacts. Nucleic Acids Research (London) 46 (6), pp. 2868 - 2882 (2018)

Klaßen, C.; Karabinskaya, A.; Dejager, L.; Vettorazzi, S.; Van Moorleghem, J.; Lühder, F.; Meijsing, S. H.; Tuckermann, J. P.; Bohnenberger, H.; Libert, C. et al.; Reichardt, H. M.: Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma. Journal of Immunology 199 (1), pp. 48 - 61 (2017)

Love, M. I.; Huska, M.; Jurk, M.; Schöpflin, R.; Starick, S. R.; Schwahn, K.; Cooper, S. B.; Yamamoto, K. R.; Thomas-Chollier, M.; Vingron, M. et al.; Meijsing, S. H.: Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation. Nucleic Acids Research (London) 45 (4), pp. 1805 - 1819 (2017)

Birth, P.; Schöne, S.; Stelzl, U.; Meijsing, S. H.: Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor. PLoS One 12 (7), e0181219 (2017)

Batalha, V.; Ferreira, D. G.; Coelho, J. E.; Valadas, J. S.; Gomes, R.; Temido-Ferreira, M.; Shmidt, T.; Baqi, Y.; Buée, L.; Müller, C. E. et al.; Hamdane, M.; Outeiro, T. F.; Bader, M.; Meijsing, S.; Sadri-Vakili, G.; Blum, D.; Lopes, L. V.: The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Scientific Reports 6, 31493 (2016)

Telorac, J.; Prykhozhij, S.; Schöne, S.; Meierhofer, D.; Sauer, S.; Thomas-Chollier, M.; Meijsing, S. H.: Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements. Nucleic Acids Research (London) 44 (13), pp. 6142 - 6156 (2016)

Schöne, S.; Jurk, M.; Helabad, M. B.; Dror, I.; Lebars, I.; Kieffer, B.; Imhof, P.; Rohs, R.; Vingron, M.; Thomas-Chollier, M. et al.; Meijsing, S.: Corrigendum: Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity. Nature Communications 7, 13784 (2016)

Schöne, S.; Jurk, M.; Helabad, M. B.; Dror, I.; Lebars, I.; Kieffer, B.; Imhof, P.; Rohs, R.; Vingron, M.; Thomas-Chollier, M. et al.; Meijsing, S.: Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity. Nature Communications 7, 12621 (2016)

Starick, S. R.; Ibn-Salem, J.; Jurk, M.; Hernandez, C.; Love, M. I.; Chung, H.-R.; Vingron, M.; Thomas-Chollier, M.; Meijsing, S. H.: ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors. Genome Res 25 (6), pp. 825 - 835 (2015)

Thomas-Chollier, M.; Watson, L. C.; Cooper, S. B.; Pufall, M. A.; Liu, J. S.; Borzym, K.; Vingron, M.; Yamamoto, K. R.; Meijsing, S. H.: A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms. Proceedings of the National Academy of Sciences of the United States of America 110 (44), pp. 17826 - 17831 (2013)

Prykhozhij, S.; Marsico, A.; Meijsing, S.: Zebrafish Expression Ontology of Gene Sets (ZEOGS): a tool to analyze enrichment of zebrafish anatomical terms in large gene sets. Zebrafish 10 (3), pp. 303 - 315 (2013)

Ziv, L.; Muto, A.; Schoonheim, P. J.; Meijsing, S. H.; Strasser, D.; Ingraham, H. A.; Schaaf, M. J.; Yamamoto, K. R.; Baier, H.: An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Molecular Psychiatry 18 (6), pp. 681 - 91 (2012)

DeKelver, R. C.; Choi, V. M.; Moehle, E. A.; Paschon, D. E.; Hockemeyer, D.; Meijsing, S. H.; Sancak, Y.; Cui, X.; Steine, E. J.; Miller, J. C. et al.; Tam, P.; Bartsevich, V. V.; Meng, X.; Rupniewski, I.; Gopalan, S. M.; Sun, H. C.; Pitz, K. J.; Rock, J. M.; Zhang, L.; Davis, G. D.; Rebar, E. J.; Cheeseman, I. M.; Yamamoto, K. R.; Sabatini, D. M.; Jaenisch, R.; Gregory, P. D.; Urnov, F. D.: Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Research 20 (8), pp. 1133 - 1142 (2010)