Publications of Bernd Timmermann

Koch, F.; Scholze, M.; Wittler, L.; Schifferl, D.; Sudheer, S.; Grote, P.; Timmermann, B.; Macura, K.; Herrmann, B. G.: Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors. Developmental Cell 42, pp. 514 - 526 (2017)

Lim, S.-Y.; Macheleidt, I.; Dalvi, P.; Schäfer, S. C.; Kerick, M.; Ozretić, L.; Ortiz-Cuaran, S.; George, J.; Merkelbach-Bruse, S.; Wolf, J. et al.; Timmermann, B.; Thomas, R. K.; Schweiger, M. R.; Buettner, R.; Odenthal, M.: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells. Scientific Reports 7, 7:10292 (2017)

Yang, J.; Moeinzadeh, M. H.; Kuhl, H.; Helmuth, J.; Xiao, P.; Haas, S.; Liu, G.; Zheng, J.; Sun, Z.; Fan, W. et al.; Deng, G.; Wang, H.; Hu, F.; Zhao, S.; Fernie, A. R.; Börno, S. T.; Timmermann, B.; Zhang, P.; Vingron, M.: Haplotype-resolved sweet potato genome traces back its hexaploidization history. Nature Plants 2017 (3), pp. 696 - 703 (2017)

Zheng-Bradley, X.; Streeter, I.; Fairley, S.; Richardson, D.; Clarke, L.; Flicek, P.; 1000 Genomes Project , C.; Timmermann, B.: Alignment of 1000 Genomes Project Reads to Reference Assembly GRCh38. GigaScience 6 (7), pp. 1 - 8 (2017)

Lange, L.; Marks, M.; Liu, J.; Wittler, L.; Bauer, H.; Piehl, S.; Bläß, G.; Timmermann, B.; Herrmann, B. G.: Pattering and gastrulation deffects caused by the tw18 lethal are due to loss of Ppp2r1a. Biology Open 6 (6), pp. 752 - 764 (2017)

Xu, S.; Brockmoeller, T.; Navarro-Quezada, A.; Kuhl, H.; Gase, K.; Ling, Z.; Zhou, W.; Kreitzer, C.; Stanke, M.; Tang, H. et al.; Lyons, E.; Pandey, P.; Pandey, S. P.; Timmermann, B.; Gaquerel, E.; Baldwin, I. T.: Wild tobacco genomes reveal the evolution of nicotine biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 114 (23), pp. 6133 - 6138 (2017)

Twardziok, M.; Meierhofer, D.; Börno, S. T.; Timmermann, B.; Jäger, S.; Boral, S.; Eggert, A.; Delebinski, C. I.; Seifeert, G.: Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses. BMC Complementary and Alternative Medicine 2017, 17:237 (2017)

Lienhard, M.; Grasse, S.; Rolff, J.; Frese, S.; Schirmer, U.; Becker, M.; Börno, S. T.; Timmermann, B.; Chavez, L.; Sültmann, H. et al.; Leschber, G.; Fichtner, I.; Schweiger, M. R.; Herwig, R.: QSEA – modelling of genome-wide DNA methylation from sequencing enrichment experiments. Nucleic Acids Research (London) 45 (6), e44 (2017)

Andrey, G.; Schöpflin, R.; Jerković, I.; Heinrich, V.; Ibrahim, D.; Paliou, C.; Hochradel, M.; Timmermann, B.; Haas, S.; Vingron, M. et al.; Mundlos, S.: Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding. Genome Research 27 (2), pp. 223 - 233 (2017)

Hussong, M.; Kaehler, C.; Kerick, M.; Grimm, C.; Franz, A.; Timmermann, B.; Welzel, F.; Isensee, J.; Hucho, T.; Krobitsch, S. et al.; Schweiger, M. R.: The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Research (London) 45 (1), pp. 382 - 394 (2017)

Franke, M.; Ibrahim, D.; Andrey, G.; Schwarzer, W.; Heinrich, V.; Schöpflin, R.; Kraft, K.; Kempfer, R.; Jerković, I.; Chan, W.-L. et al.; Spielmann, M.; Timmermann, B.; Wittler, L.; Kurth, I.; Cambiaso, P.; Zuffardi, O.; Houge, G.; Lambie, L.; Brancati, F.; Pombo, A.; Vingron, M.; Spitz, F.; Mundlos, S.: Formation of novel chromatin domains determines pathogenicity of genomic duplications. Nature 538 (7624), pp. 265 - 269 (2016)

Poznik, G. D.; Xue, Y.; Mendez, F. L.; Willems, T. F.; Massaia, A.; Wilson Sayres, M. A.; The 1000 Genomes Projekt, C.; Lehrach, H.; Sudbrak, R.; Albrecht, M. W. et al.; Amstislavskiy, V.; Borodina, T. A.; Lienhard, M.; Mertes, F.; Sultan, M.; Timmermann, B.; Yaspo, M.-L.: Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences. Nature Genetics 48 (6), pp. 593 - 599 (2016)

Broecker, F.; Hardt, C.; Herwig, R.; Timmermann, B.; Kerick, M.; Wunderlich, A.; Schweiger, M. R.; Borsig, L.; Heikenwalder, M.; Lehrach, H. et al.; Moelling, K.: Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line. The FEBS Journal 283 (9), pp. 1669 - 1688 (2016)

Mueller, J. C.; Kuhl, H.; Timmermann, B.; Kempenaers, B.: Characterization of the genome and transcriptome of the blue tit Cyanistes caeruleus: polymorphisms, sex-biased expression and selection signals. Molecular Ecology Resources 16 (2), pp. 549 - 561 (2016)

Alam, M. T.; Zelezniak, A.; Mülleder, M.; Shliaha, P.; Schwarz, R.; Capuano, F.; Vowinckel, J.; Radmanesfahar , E.; Krüger, A.; Calvani , E. et al.; Michel, S.; Börno, S. T.; Christen, S.; Patil , K. R.; Timmermann, B.; Lilley, K. S.; Ralser, M.: The metabolic background is a global player in Saccharomyces gene expression epistasis. Nature Microbiology 2016, 15030 (2016)

Spier, I.; Kerick, M.; Drichel, D.; Horpaopan, S.; Altmüller, J.; Laner, A.; Holzapfel, S.; Peters, S.; Adam, R.; Zhao, B. et al.; Becker, T.; Lifton, R. P.; Holinski-Feder, E.; Perner, S.; Thiele, H.; Nöthen, M. M.; Hoffmann, P.; Timmermann, B.; Schweiger, M. R.; Aretz, S.: Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis. Famillial Cancer 2016, pp. 1 - 8 (2016)

Spier, I.; Drichel, D.; Kerick, M.; Kirfel, J.; Horpaopan, S.; Laner, A.; Holzapfel, S.; Peters, S.; Adam, R.; Zhao, B. et al.; Becker, T.; Lifton, R. P.; Perner, S.; Hoffmann, P.; Kristiansen, G.; Timmermann, B.; Nöthen, M. M.; Holinski-Feder, E.; Schweiger, M. R.; Aretz, S.: Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases. Journal of Medical Genetics, 103468 (2015)

Mertes, F.; Lichtner, B.; Kuhl, H.; Blattner , M.; Otte, J.; Wruck, W.; Timmermann, B.; Lehrach, H.; Adjaye, J.: Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC Genomics 16, 16:925 (2015)

Satzger, I.; Marks, L.; Kerick, M.; Klages, S.; Berking, C.; Herbst, R.; Völker, B.; Schacht, V.; Timmermann, B.; Gutzmer, R.: Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanoma. Oncotarget 2015, 5634 (2015)

Sudmant, P. H.; Rausch, T.; Gardner, E. J.; Handsaker, R. E.; Abyzov, A.; Huddleston, J.; The 1000 Genomes Project Consortium; Timmermann, B.; Herwig, R.; Lehrach, H.: An integrated map of structural variation in 2,504 human genomes. Nature 526 (7571), pp. 75 - 81 (2015)