Publications of David Meierhofer

Zhang, Y.; Stöppelkamp, I.; Fernandez-Pernas, P.; Allram, M.; Charman, M.; Magalhães, A. P.; Piedavent-Salomon, M.; Sommer, G.; Sung, Y.-C.; Meyer, K. et al.; Grams, N.; Halko, E.; Dongre, S.; Meierhofer, D.; Malszycki, M.; Ilik, I. A.; Aktas, T.; Kraushar, M. L.; Vastenhouw, N.; Weitzman, M. D.; Grebien, F.; Niskanen, H.; Hnisz, D.: Probing condensate microenvironments with a micropeptide killswitch. Nature (2025)

Key, J.; Almaguer-Mederos, L.-E.; Reddy Kandi, A.; Sen, N.-E.; Gispert, S.; Köpf, G.; Meierhofer, D.; Auburger, G.: ATXN2L primarily interacts with NUFIP2, the absence of ATXN2L results in NUFIP2 depletion, and the ATXN2-polyQ expansion triggers NUFIP2 accumulation. Neurobiology of Disease 209, Article 106903 (2025)

Kopp, J.; Jahn, D.; Vogt, G.; Psoma, A.; Ratto, E.; Morelle, W.; Stelzer, N.; Hausser , I.; Hoffmann, A.; de Los Santos, M. R. et al.; Koch, L. A.; Fischer-Zirnsak, B.; Thiel, C.; Palm, W.; Meierhofer, D.; van den Bogaart, G.; Foulquie, F.; Meinhardt, A.; Kornak, U.: Golgi pH elevation due to loss of V-ATPase subunit V0a2 function correlates with tissue-specific glycosylation changes and globozoospermia. Cellular and Molecular Life Sciences 82 (1), Article 4 (2024)

Guo , J.; Krehl, K.; Safraou, Y.; Wallach, I.; Braun, J.; Meierhofer, D.; Sack, I.; Berndt , N.: Pregnancy alters fatty acid metabolism, glucose regulation, and detoxification of the liver in synchrony with biomechanical property change. Heliyon 10 (20), Article e39674. (2024)

Tsaytler, P.; Blaess, G.; Scholze-Wittler, M.; Meierhofer, D.; Wittler, L.; Koch, F.; Herrmann, B. G.: SRF promotes long-range chromatin loop formation and stem cell pluripotency. Cell Reports 43 (10), 114846 (2024)

Lisowski, P.; Lickfett, S.; Rybak-Wolf, A.; Menacho, C.; Le, S.; Pentimalli, T. M.; Notopoulou, S.; Dykstra, W.; Oehler, D.; López-Calcerrada, S. et al.; Mlody, B.; Otto, M.; Wu, H.; Richter, Y.; Roth, P.; Anand, R.; Kulka, L. A. M.; Meierhofer, D.; Glazar, P.; Legnini, I.; Telugu, N. S.; Hahn, T.; Neuendorf, N.; Miller, D. C.; Böddrich, A.; Polzin, A.; Mayatepek, E.; Diecke, S.; Olzscha, H.; Kirstein, J.; Ugalde, C.; Petrakis, S.; Cambridge, S.; Rajewsky, N.; Kühn, R.; Wanker, E. E.; Priller, J.; Metzger, J. J.; Prigione, A.: Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nature Communications 15 (1), Article 7027 (2024)

Ulicevic, J.; Shao, Z.; Jasnovidova, O.; Bressin, A.; Gajos, M.; Ng, A. H.; Annaldasula, S.; Meierhofer, D.; Church, G. M.; Busskamp, V. et al.; Mayer, A.: Uncovering the dynamics and consequences of RNA isoform changes during neuronal differentiation. Molecular Systems Biology 20 (7), pp. 767 - 798 (2024)

Borisova, E.; Newman, A. G.; Couce Iglesias, M.; Dannenberg, R.; Schaub, T.; Qin, B.; Rusanova, A.; Brockmann, M.; Koch, J.; Daniels, M. et al.; Turko, P.; Jahn, O.; Kaplan, D. R.; Rosário, M.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Meierhofer, D.; Kraushar, M. L.; Tarabykin, V.; Ambrozkiewicz, M. C.: Protein translation rate determines neocortical neuron fate. Nature Communications 15 (1), Article 4879 (2024)

Kudrin, P.; Singh, A.; Meierhofer, D.; Kuśnierczyk, A.; Ørom, U. A. V.: N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules. EMBO Reports 25 (4), pp. 1814 - 1834 (2024)

Ilik, I. A.; Glažar, P.; Tse, K.; Brändl, B.; Meierhofer, D.; Müller, F.-J.; Smith, Z. D.; Aktas, T.: Autonomous transposons tune their sequences to ensure somatic suppression. Nature 626 (8001), pp. 1116 - 1124 (2024)

Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Disrupted degradative sorting of TLR7 is associated with human lupus. Science Immunology 9 (92), Article eadi9575 (2024)

Key, J.; Gispert, S.; Reddy Kandi , A.; Heinz, D.; Hamann, A.; Osiewacz, H. D.; Meierhofer, D.; Auburger, G.: CLPP-Null Eukaryotes with Excess Heme Biosynthesis Show Reduced L-arginine Levels, Probably via CLPX-Mediated OAT Activation. Biomolecules 14 (2), Article 241 (2024)

van der Weijden, V. A.; Stötzel, M.; Iyer, D. P.; Fauler, B.; Gralinska, E.; Shahraz, M.; Meierhofer, D.; Vingron, M.; Rulands, S.; Alexandrov, T. et al.; Mielke, T.; Bulut-Karslioglu, A.: FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy. Nature Cell Biology 26 (2), pp. 181 - 193 (2024)

Basu, S.; Martínez-Cristóbal, P.; Frigolé-Vivas, M.; Pesarrodona, M.; Lewis, M.; Szulc, E.; Bañuelos, C. A.; Sánchez-Zarzalejo, C.; Bielskutė, S.; Zhu, J. et al.; Pombo-García, K.; Garcia-Cabau, C.; Zodi, L.; Dockx, H.; Smak, J.; Kaur, H.; Batlle, C.; Mateos, B.; Biesaga, M.; Escobedo, A.; Bardia, L.; Verdaguer, X.; Ruffoni, A.; Mawji, N. R.; Wang, J.; Obst, J. K.; Tam, T.; Brun-Heath, I.; Ventura, S.; Meierhofer, D.; García, J.; Robustelli, P.; Stracker, T. H.; Sadar, M. D.; Riera, A.; Hnisz, D.; Salvatella, X.: Rational optimization of a transcription factor activation domain inhibitor. Nature Structural & Molecular Biology 30 (12), pp. 1958 - 1969 (2023)

Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A. et al.; Meierhofer, D.; Hauck, F.; Majer, O.: Endosome dysfunction leads to gain-of-function TLR7 and human lupus. bioRxiv (Preprint Server) (2023)

Weigert, R.; Hetzel, S.; Bailly, N.; Haggerty, C.; Ilik, I. A.; Kwong Yung, P. Y.; Navarro, C.; Bolondi, A.; Sampath Kumar, A.; Anania, C. et al.; Brändl, B.; Meierhofer, D.; Lupiáñez, D. G.; Müller, F.-J.; Aktas, T.; Elsässer, S. J.; Kretzmer, H.; Smith, Z. D.; Meissner, A.: Dynamic antagonism between key repressive pathways maintains the placental epigenome. Nature Cell Biology 25 (4), pp. 579 - 591 (2023)

Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S. D.; Braendl, B.; Gießelmann, P. et al.; Tornisiello, R.; Mohan Parsi, K.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.: T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. eLife 12, Article e83077 (2023)

Shahryari, M.; Keller, S.; Meierhofer, D.; Wallach, I.; Safraou, Y.; Guo, J.; Marticorena Garcia, S. R.; Braun, J.; Makowski, M. R.; Sack, I. et al.; Berndt, N.: On the relationship between metabolic capacities and in vivo viscoelastic properties of the liver. Frontiers in Bioengineering and Biotechnology 10, 1042711 (2023)

Witt, N.; Galante, D.; Andreotti, S.; Glil, M. A.; Fasanella, A.; Meierhofer, D.; Tomaso, H.: Identification of Universally Applicable and Species-Specific Marker Peptides for Bacillus anthracis. Life 12 (10), 1549 (2022)

Berndt, N.; Hudert, C. A.; Eckstein, J.; Loddenkemper, C.; Henning, S.; Bufler, P.; Meierhofer, D.; Sack, I.; Wiegand, S.; Wallach, I. et al.; Holzhütter, H.-G.: Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences 23 (19), 11072 (2022)