Max Planck Institute for Molecular Genetics

Publications

The following publications were published exclusively under the affiliation of the Max Planck Society. For publications by the principal investigator outside of the Max Planck Society, see the links on the lower left.

Journal Article (469)

Journal Article

Jatzlau, J.; Trumpp, M.; Kühlwein, J.; Obendorf, L.; Le, Y.; Kuhl, H.; Preussner, M.; Mendez, P.-L.; Burkert, H.; Burdzinski, W. et al.; Mundlos, S.; Winkler, C.; Stöck, M.; Knaus, P.: Recurrent evolution of ligand-binding domain multiplicity fine-tunes TGFβ signaling in vertebrates. Nature Communications 17, 4458 (2026)

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Lo, B.-W.; Lin, H.-F.; Kong, S.-W.; Wu, W.-J.; Peng, Y.-L.; Wang, S. C.-L.; Lu, X.; Wang, H.-Y.: Genomes of Wiebesia fig wasps reveal the adaptation and codiversification in the fig-fig wasp mutualism. Genome Biology and Evolution (2026)

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Ringel, A. R.; Benetti, N.; Magg, A.; Groll, F.; Schöpflin, R.; Kühnlein, M.; Stiege, A. C.; Fischer, U.; Wittler, L.; Game, L. et al.; Lorenz, S.; Young, G.; Mundlos, S.; Allou, L.: Temporal loss ofEn1during limb development causes distinct phenotypes. Genes & Development (2026)

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Boschann, F.; Kopp, J.; Römer, S.; Küchler, O.; Lyubenova, H.; von Kügelgen, N.; Hertstein, E.; Hagelstein, L.; Becker, C.; Becker, K. et al.; Brachs, S.; Mai, K.; Meierhofer, D.; Seelow, D.; Mundlos, S.; Horn, D.; Schuelke, M.; Fischer-Zirnsak, B.: A biallelic MRPL42 variant causes a combined oxidative phosphorylation deficiency syndrome revealed by multi-omics. npj Genomic Medicine 11, 20 (2026)

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Bell, C. C.; de Boer, C. G.; Camellato, B. R.; Delás, M. J.; Ibrahim, D. M.; Montgomery, M. T.: How to build the regulatory genome: a constructionist guide to the cis-regulatory code. Development 153 (2026)

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Rezvani, M.; Quach, S.; Lewis, K.; Saiki, N.; Xue, C.; Kimura, M.; Iwasawa, K.; Weihs, J.; Elzobair, T.; Al Reza, H. et al.; Cai, Y.; Zhang, R.; Milton, Y.; Chaturvedi, P.; Thorner, K.; Nayak, R. C.; Munera, J.; Kramer, P.; Davis, B. R.; Balamurugan, A. N.; Ahmed, Y. A.; Finke, M.; Behncke, R. Y.; Guillot, A.; Hägerling, R.; Polansky, J. K.; Bufler, P.; Cancelas, J. A.; Zorn, A.; Wells, J. M.; Yoshimoto, M.; Takebe, T.: Modeling Immune Lineage Co-Development in Human Pluripotent Stem Cell-derived Liver Organoids. Journal of Hepatology (2025)

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Funk, E. M.; Jafree, D. J.; Hansmeier, N. R.; Abad Baucells, C.; Behncke, R. Y.; Pomeranz, G.; Kolatsi-Joannou, M.; Mason, W. J.; Moulding, D.; Russell, L. G. et al.; Subramanian, A.; Ulferts, S.; Wilson, L.; Long, D. A.; Hägerling, R.: Nanobody Immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in mice. Journal of Nanobiotechnology 23, 667 (2025)

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Jacobs, J.; Lyubenova, H.; Potelle, S.; Kopp, J.; Gerin, I.; Chan, W. L.; Rodriguez de los Santos, M.; Hülsemann, W.; Mensah, M. A.; Cormier-Daire, V. et al.; Joosten, M.; Bruggenwirth, H. T.; Stuurman, K. E.; Miranda, V.; Campeau, P. M.; Wittler, L.; Graff, J.; Mundlos, S.; Ibrahim, D. M.; Van Schaftingen, E.; Fischer-Zirnsak, B.; Kornak, U.; Ehmke, N.; Bommer, G. T.: A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia. Nature (2025)

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Garrett, A.; Kalscheuer, V. M.; Figueroa, R. R.; Palmer, E. E.; Morgan, A. T.: CLCN4‐Related Neurodevelopmental Condition: Characterization of Speech and Language Abilities. American Journal of Medical Genetics Part A (2025)

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Schindler, M.; Feregrino, C.; Aldrovandi, S.; Lo, B.-W.; Monaco, A. A.; Ringel, A. R.; Morales, A. E.; Zehnder, T.; Behncke, R. Y.; Glaser, J. et al.; Barclay, A.; Andrey, G.; Kragesteen, B. K.; Hägerling, R.; Haas, S.; Vingron, M.; Ulitsky, I.; Marti-Renom, M. A.; Hechavarria, J.; Fasel, N.; Hiller, M.; Lupiáñez, D. G.; Mundlos, S.; Martinez Real, F.: Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development. Nature Ecology & Evolution (2025)

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Glaser, J.; Cova, G.; Fauler, B.; Prada-Medina, C. A.; Stanislas, V.; Phan, M. H. Q.; Schöpflin, R.; Aktas, Y.; Franke, M.; Andrey, G. et al.; Paliou, C.; Laupert, V.; Chan, W.-L.; Wittler, L.; Mielke, T.; Mundlos, S.: Enhancer adoption by an LTR retrotransposon generates viral-like particles causing developmental limb phenotypes. Nature Genetics 57, pp. 1766 - 1776 (2025)

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Nordin, A.; Chakraborty, C.; Jonasson, M.; Dano, O.; Zambanini, G.; Pagella, P.; Remeseiro, S.; Cantù, C.: Wnt signaling activation induces CTCF binding and loop formation atcis-regulatory elements of target genes. Genome Research 35, pp. 1701 - 1716 (2025)

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Groeneweg, S.; van Geest, F. S.; van der Most, F.; Abela, L.; Alfieri, P.; Bauer, A. J.; Bertini, E.; Cappa, M.; Çelik, N.; de Coo, I. F. M. et al.; Dolcetta-Capuzzo, A.; Dubinski, I.; Granadillo, J. L.; Hoefsloot, L. H.; Kalscheuer, V. M.; van der Knoop, M. M.; Krude, H.; McNerney, K. P.; Paone, L.; Peeters, R. P.; Peters, C.; Schuelke, M.; Schweizer, U.; Sprague, J. E.; van Trotsenburg, A. S. P.; Wilpert, N.-M.; Zanni, G.; van Zutven, L. J. C. M.; Visser, W. E.: MCT8 deficiency in females. Journal of Clinical Endocrinology and Metabolism (2025)

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Phan, M. H. Q.; Zehnder, T.; Puntieri, F.; Magg, A.; Majchrzycka, B.; Antonović, M.; Wieler, H. M.; Lo, B.-W.; Baranasic, D.; Lenhard, B. et al.; Müller, F.; Vingron, M.; Ibrahim, D. M.: Conservation of regulatory elements with highly diverged sequences across large evolutionary distances. Nature Genetics 57, pp. 1524 - 1534 (2025)

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Hurtado, A.; Mota-Gómez, I.; Lao, M.; Real, F. M.; Jedamzick, J.; Burgos, M.; Lupiáñez, D. G.; Jiménez, R.; Barrionuevo, F. J.: Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster. Nature Communications 15 (1), Article 3809 (2025)

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Lo, B.-W.; Martinez Real, F.; Magg, A.; Wise Sr., J.; Mundlos, S.; Franchini, P.: Genome-wide demographic analyses of balaenid whales revealed complex history of gene flow associated with past climate oscillation. Genome Biology and Evolution 17 (5), Article evaf081 (2025)

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Damiani, F.; Giuliano, M. G.; Cornuti, S.; Putignano, E.; Tognozzi, A.; Suckow, V.; Kalscheuer, V. M.; Pizzorusso, T.; Tognini, P.: Multi-site investigation of gut microbiota in CDKL5 deficiency disorder mouse models: Targeting dysbiosis to improve neurological outcomes. Cell Reports 44 (4), Article 115546 (2025)

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Altendorfer, E.; Mundlos, S.; Mayer, A.: A transcription coupling model for how enhancers communicate with their target genes. Nature Structural & Molecular Biology 32 (4), pp. 598 - 606 (2025)

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Berghöfer, J.; Khaveh, N.; Mundlos, S.; Metzger, J.: Multi-tool copy number detection highlights common body size-associated variants in miniature pig breeds from different geographical regions. BMC Genomics 26 (1), Article 285 (2025)

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Wang, M.; Di Pietro-Torres, A.; Feregrino, C.; Luxey, M.; Moreau, C.; Fischer, S.; Fages, A.; Ritz, D.; Tschopp, P.: Distinct gene regulatory dynamics drive skeletogenic cell fate convergence during vertebrate embryogenesis. Nature Communications 16 (1), Article 2187 (2025)

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