Publications of David Meierhofer

Holzhütter, H.-G.; Wuensch, T.; Gajowski, R.; Berndt, N.; Bulik, S.; Meierhofer, D.; Stockmann, M.: A novel variant of the 13C-methacetin liver function breath test that eliminates the confounding effect of individual differences in sytemic CO2 kinetics. Archives of Toxicology 94 (2), pp. 401 - 415 (2020)

Kolbe, E.; Aleithe, S.; Rennert, C.; Spormann, L.; Ott, F.; Meierhofer, D.; Gajowski, R.; Stöpel, C.; Hoehme, S.; Kücken, M. et al.; Brusch, L.; Seifert, M.; von Schoenfels, W.; Schafmayer, C.; Brosch, M.; Hoffmann, U.; Damm, G.; Seehofer, D.; Hampe, J.; Gebhardt, R.; Matz-Soja, M.: Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human. Cell Reports 29 (13), pp. 4553 - 4567 (2019)

Sen, N.-E.; Arsovic, A.; Meierhofer, D.; Brodesser, S.; Oberschmidt, C.; Canet-Pons, J.; Kaya, Z.-E.; Halbach, M.-V.; Gispert, S.; Sandhoff, K. et al.; Auburger, G.: In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism. International Journal of Molecular Sciences 20 (23), 5854 (2019)

Muller, X.; Schlegel, A.; Kron, P.; Eshmuminov, D.; Würdinger, M.; Meierhofer, D.; Clavien, P.-A.; Dutkowski, P.: Novel Real-Time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation. Annals of Surgery 270 (5), pp. 783 - 790 (2019)

Ni, Y.; Hagras, M. A.; Konstantopoulou, V.; Mayr, J. A.; Stuchebrukhov , A. A.; Meierhofer, D.: Mutations in NDUFS1 Cause Metabolic Reprogramming and Disruption of the Electron Transfer. Cells 8 (10), E1149 (2019)

Alahmad, A.; Paffrath, V.; Clima, R.; Busch, J. F.; Rabien, A.; Kilic, E.; Villegas, S.; Timmermann, B.; Attimonelli, M.; Jung, K. et al.; Meierhofer, D.: Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation. Cancers 11 (9), 1298 (2019)

Guo, J.; Bertalan, G.; Meierhofer, D.; Klein, C.; Schreyer, S.; Steiner, B.; Wang, S.; Vieira da Silva, R.; Infante-Duarte, C.; Koch, S. et al.; Boehm-Sturm, P.; Braun, J.; Sack, I.: Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity. Acta Biomaterialia 99, pp. 433 - 442 (2019)

Meierhofer, D.: Acylcarnitine profiling by low-resolution LC-MS. PLoS One 14 (8), e0221342 (2019)

Xiao, Y.; Meierhofer, D.: Are hydroethidine-based probes reliable for ROS detection? ANTIOXIDANTS & REDOX SIGNALING 31 (4), pp. 359 - 367 (2019)

Sen, N.-E.; Canet-Pons, J.; Halbach, M. V.; Arsovic, A.; Pilatus, U.; Chae, W.-H.; Kaya, Z.-E.; Seidel, K.; Rollmann, E.; Mittelbronn, M. et al.; Meierhofer, D.; De Zeeuw, C. I.; Bosman, L. W. J.; Gispert, S.; Auburger, G.: Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation. Neurobiology of Disease 132, 104559 (2019)

Xiao, Y.; Meierhofer, D.: Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies. International Journal of Molecular Sciences 20 (15), E3672 (2019)

Berndt , N.; Eckstein, J.; Heucke, N.; Gajowski, R.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: Characterization of Lipid and Lipid Droplet Metabolism in Human HCC. Cells 8 (5), 512 (2019)

Hudert, C. A.; Selinski, S.; Rudolph, B.; Bläker, H.; Loddenkemper, C.; Thielhorn, R.; Berndt, N.; Golka, K.; Cadenas, C.; Reinders, J. et al.; Henning, S.; Bufler, P.; Jansen, P. L. M.; Holzhütter, H.; Meierhofer, D.; Hengstler, J. G.; Wiegand, S.: Genetic determinants of steatosis and fibrosis progression in paediatric non‐alcoholic fatty liver disease. Liver International 39 (3), pp. 540 - 556 (2019)

Berndt, N.; Bulik, S.; Wallach, I.; Wünsch, T.; König, M.; Stockmann, M.; Meierhofer, D.; Holzhütter, H.-G.: HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology. Nature Communications 9 , 9:2386 (2018)

Baek, J. Y.; Geissner, A.; Rathwell, D. C. K.; Meierhofer, D.; Pereira, C. L.; Seeberger , P.: A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate. Chemical Science 9 (5), pp. 1279 - 1288 (2018)

Kürschner, G.; Zhang, Q.; Clima, R.; Xiao , Y.; Busch, J. F.; Kilic, E.; Jung, K.; Berndt, N.; Bulik, S.; Holzhütter, H.-G. et al.; Gasparre, G.; Attimonelli, M.; Babu, M.; Meierhofer, D.: Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione. Oncotarget 2017, 8:105882-105904 (2017)

Corwin, T.; Woodsmith, J.; Apelt, F.; Fontaine, J.-F.; Meierhofer, D.; Helmuth, J.; Grossmann, A.; Andrade-Navarro, M. A.; Ballif, B. A.; Stelzl, U.: Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate. Cell Systems 5 (2), e4, pp. 128 - 139 (2017)

Torres-Odio, S.; Key, J.; Hoepken, H.-H.; Canet-Pons, J.; Valek, L.; Roller, B.; Walter, M.; Morales-Gordo, B.; Meierhofer, D.; Harter, P. N. et al.; Mittelbronn, M.; Tegeder, I.; Gispert, S.; Auburger, G.: Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. Journal of Neuroinflammation 14 (1), 14:154 (2017)

Auburger, G.; Sen, N.-E.; Meierhofer, D.; Başak, A.-N.; Gitler, A. D.: Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2. Trends in Neurosciences 40 (8), pp. 507 - 516 (2017)

Lorenz, C.; Lesimple, P.; Bukowiecki, R.; Zink, A.; Inak, G.; Mlody, B.; Singh, M.; Semtner, M.; Mah, N.; Auré, K. et al.; Leong, M.; Zabiegalov, O.; Lyras, E.-M.; Pfiffer, V.; Fauler, B.; Eichhorst, J.; Wiesner, B.; Huebner, N.; Priller, J.; Mielke, T.; Meierhofer, D.; Izsvák, Z.; Meier, J. C.; Bouillaud, F.; Adjaye, J.; Schuelke, M.; Wanker, E. E.; Lombès, A.; Prigione, A.: Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders. Cell Stem Cell 20 (5), e9, pp. 659 - 674 (2017)