Publikationen von Christoph K. Wierling

Wasco Wruck, Karl Kashofer, Samrina Rehman, Andriani Daskalaki, Daniela Berg, Ewa Gralka, Justyna Jozefczuk, Katharina Drews, Vikash Pandey, Christian Regenbrecht, Christoph K. Wierling, Paola Turano, Ulrike Korf, Kurt Zatloukal, Hans Lehrach, Hans V. Westerhoff, and James Adjaye, "Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.," Scientific Data 2, 150068 (2015).

Christoph K. Wierling, Thomas Kessler, Lesley A. Ogilvie, Bodo Lange, Marie-Laure Yaspo, and Hans Lehrach, "Network and systems biology: essential steps in virtualising drug discovery and development.," Drug Discovery Today: Technology 15, 33-40 (2015).

V. Pandey, M. Sultan, K. Kashofer, M. Ralser, V. Amstislavskiy, J. Starmann, I. Osprian, C. Grimm, H. Hache, M. L. Yaspo, H. Sultmann, M. Trauner, H. Denk, K. Zatloukal, H. Lehrach, and C. Wierling, "Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains," PLoS One 9 (10), e111006 (2014).

C. Röhr, M. Kerick, A. Fischer, A. Kuehn, K. Kashofer, B. Timmermann, A. Daskalaki, T. Meinel, D. Drichel, S. Börno, A. Nowka, S. Krobitsch, A. C. McHardy, C. Kratsch, T. Becker, A. Wunderlich, C. Barmeyer, C. Viertler, K. Zatloukal, C. Wierling, H. Lehrach, and M.-R. Schweiger, "High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications," PLoS One 8 (7), e67461-e67461 (2013).

F. Götschel, D. Berg, W. Gruber, C. Bender, M. Eberl, M. Friedel, J. Sonntag, E. Rungeler, H. Hache, C. K. Wierling, W. Nietfeld, H. Lehrach, A. Frischauf, R. Schwartz-Albiez, F. Aberger, and U. Korf, "Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expression of GLI1," PLoS One 8 (6), e65403-e65403 (2013).

T. Kessler, H. Hache, and C. Wierling, "Integrative analysis of cancer-related signaling pathways," Frontiers in Physiology 4, 4:124-4:124 (2013).

Christoph Wierling, Alexander Kühn, Hendrik Hache, Andriani Daskalaki, Elisabeth Maschke-Dutz, Svetlana Peycheva, Jian Li, Ralf Herwig, and Hans Lehrach, "Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment," Mutation Research-Genetic Toxixology and Environmental Mutagenesis 746 (2), 163-170 (2012).

M. Eberl, S. Klingler, D. Mangelberger, A. Loipetzberger, H. Damhofer, K. Zoidl, H. Schnidar, H. Hache, H. C. Bauer, F. Solca, C. Hauser-Kronberger, A. N. Ermilov, M. E. Verhaegen, C. K. Bichakjian, A. A. Dlugosz, W. Nietfeld, M. Sibilia, H. Lehrach, C. Wierling, and F. Aberger, "Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells," EMBO Molecular Medicine 4 (3), 218-233 (2012).

J. Li, V. Pandey, T. Kessler, H. Lehrach, and C. Wierling, "Modeling of miRNA and drug action in the EGFR signaling pathway," PLoS One 7 (1), e30140 (2012).

Justyna Jozefczuk, Karl Kashofer, Ramesh Ummanni, Frauke Henjes, Samrina Rehman, Suzanne Geenen, Wasco Wruck, Chritian Regenbrecht, Andriani Daskalaki, Christoph K. Wierling, Paola Turano, Ivano Bertini, Ulrike Korf, Kurt Zatloukal, Hans V. Westerhoff, Hans Lehrach, and James Adjaye, "A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells," Frontiers in Systems Biology 3 (3), 3:339 (2012).

A. Kamburov, K. Pentchev, H. Galicka, C. Wierling, H. Lehrach, and R. Herwig, "ConsensusPathDB: toward a more complete picture of cell biology," Nucleic Acids Research (London) 39 (Database issue), D712-D717 (2011).

A. Kowald and C. Wierling, "Standards, tools, and databases for the analysis of yeast 'omics data," Methods in Molecular Biology 759, 345-65 (2011).

Alexander Kühn and Christoph Wierling, "Der virtuelle Patient - neue Wege in der Krebsforschung," Laborwelt 12 (6), 19-20 (2011).

H. Stehr, S. H. Jang, J. M. Duarte, C. Wierling, H. Lehrach, M. Lappe, and B. M. Lange, "The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors," Molecular Cancer 10, 54 (2011).

H. Hache and C. Wierling, "Computerprogramme zur Modellierung genregulatorischer Netzwerke," Laborwelt 1, 31-32 (2010).

Clemens Kühn, Christoph Wierling, Alexander Kühn, Edda Klipp, Georgia Panopoulou, Hans Lehrach, and Albert J. Poustka, "Monte-Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network.," BMC Systems Biology 3, 83-83 (2009).

Grit Nebrich, Marion Herrmann, Daniela Hartl, Madeleine Diedrich, Thomas Kreitler, Christoph Wierling, Joachim Klose, Patrick Giavalisco, Claus Zabel, and Lei Mao, "PROTEOMER: A workflow-optimized laboratory information management system for 2-D electrophoresis-centered proteomics.," Proteomics 9 (7), 1795-1808 (2009).

Hendrik Hache, Christoph Wierling, Hans Lehrach, and Ralf Herwig, "GeNGe: systematic generation of gene regulatory networks. Bioinformatics.," Bioinformatics 25 (9), 1205-1207 (2009).

Atanas Kamburov, Christoph Wierling, Hans Lehrach, and Ralf Herwig, "ConsensusPathDB—a database for integrating human functional interaction networks," Nucleic Acids Research 37 (Database issue), D623-D628 (2008).

Christoph Wierling, Ralf Herwig, and Hans Lehrach, "Resources, standards and tools for systems biology," Briefings in Functional Genomics and Proteomics 6 (3), 240-251 (2007).