Publikationen von S. R. Connell

A. H. Ratje, J. Loerke, A. Mikolajka, M. Brunner, P. W. Hildebrand, A. L. Starosta, A. Donhofer, S. R. Connell, P. Fucini, T. Mielke, P. C. Whitford, J. N. Onuchic, Y. Yu, K. Y. Sanbonmatsu, R. K. Hartmann, P. A. Penczek, D. N. Wilson, and C. M. Spahn, "Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites," Nature 468 (7324), 713-716 (2010).

Jan-Christian Jan-Christian Schuette, Frank V. Murphy, Ann C. Kelley, John R. Weir, Jan Giesebrecht, Sean R. Connell, Justus Loerke, Thorsten Mielke, Wei Zhang, Pawel A. Penczek, V. Ramakrishnan, and Christian M. T. Spahn, "GTPase activation of elongation factor EF-Tu by the ribosome during decoding.," The EMBO Journal 28 (6), 755-765 (2009).

Sean R. Connell, Maya Topf, Yan Qin, Daniel N. Wilson, Thorsten Mielke, Paola Fucini, Knud H. Nierhaus, and Christian M. T. Spahn, "A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation," Nature Structural & Molecular Biology 15 (9), 910-915 (2008).

Sean R. Connell, Maya Topf, Yan Qin, Daniel N. Wilson, Thorsten Mielke, Paola Fucini, Knud H. Nierhaus, and Christian M. T. Spahn, "A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation," Nature Structural & Molecular Biology 15 (9), 910-915 (2008).

Sean R. Connell, Maya Topf, Yan Qin, Daniel N. Wilson, Thorsten Mielke, Paola Fucini, Knud H. Nierhaus, and Christian M. T. Spahn, "A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation," Nature Structural & Molecular Biology 15 (9), 910-915 (2008).

Sean R. Connell, Chie Takemoto, Daniel N. Wilson, Hongfei Wang, Kazutaka Murayama, Takaho Terada, Mikako Shirouzu, Maximilian Rost, Martin Schüler, Jan Giesebrecht, Marylena Dabrowski, Thorsten Mielke, Paola Fucini, Shigeyuki Yokoyama, and Christian M. T. Spahn, "Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors," Molecular Cell 25 (5), 751-764 (2007).

Martin Schüler, Sean R. Connell, Aurelie Lescoute, Jan Giesebrecht, Marylena Dabrowski, Birgit Schroeer, Thorsten Mielke, Pawel A. Penczek, Eric Westhof, and Christian M. T. Spahn, "Structure of the ribosome-bound cricket paralysis virus IRES RNA," Nature Structural & Molecular Biology 13 (12), 1092-1096 (2006).

Róisín M. Owens, Gareth Pritchard, Paul Skipp, Michelle Hodey, Sean R. Connell, Knud H. Nierhaus, and C. David O'Connor, "A dedicated translation factor controls the synthesis of the global regulator Fis," EMBO Journal 23 (16), 3375-3385 (2004).

John Christodoulou, Göran Larsson, Paola Fucini, Sean R. Connell, Thelma A. Pertinhez, Charlotte L. Hanson, Christina Redfield, Knud H. Nierhaus, Carol V. Robinson, Jürgen Schleucher, and Christopher M. Dobson, "Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes," Proceedings of the National Academy of Sciences 101 (30), 10949-10954 (2004).

Robert J. C. Gilbert, Paola Fucini, Sean Connell, Stephen D. Fuller, Knud H. Nierhaus, Carol V. Robinson, Christopher M. Dobson, and David I. Stuart, "Three-dimensional structures of translating ribosomes by Cryo-EM," Molecular Cell 14 (1), 57-66 (2004).

Sean R. Connell, Dobryan M. Tracz, Knud H. Nierhaus, and Diane E. Taylor, "Ribosomal protection proteins and their mechanism of tetracycline resistance," Antimicrobial Agents and Chemotherapy 47 (12), 3675-3681 (2003).

George P. Dinos, Sean R. Connell, Knud H. Nierhaus, and Dimitrios L. Kalpaxis, "Erythromycin, roxithromycin, and clarithromycin: Use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation," Molecular Pharmacology 63 (3), 617-623 (2003).

Sean R. Connell, Catharine A. Trieber, George P. Dinos, Edda Einfeldt, Diane E. Taylor, and Knud H. Nierhaus, "Mechanism of Tet(O)-mediated tetracycline resistance," EMBO Journal 22 (4), 945-953 (2003).

Sean R. Connell, Catharine A. Trieber, Ulrich Stelzl, Edda Einfeldt, Diane E. Taylor, and Knud H. Nierhaus, "The tetracycline resistance protein Tet() perturbs the conformation of the ribosomal decoding centre," Molecular Microbiology 45 (6), 1463-1472 (2002).

Daniel N. Wilson, Gregor Blaha, Sean R. Connell, Pavel V. Ivanov, Holger Jenke, Ulrich Stelzl, Yoshika Teraoka, and Knud H. Nierhaus, "Protein Synthesis at Atomic Resolution: Mechanistics of Translation in the Light of Highly Resolved Structures for the Ribosome," Current Protein and Peptide Science 3 (1), 1-53 (2002).