Publikationen von Sara Hetzel

Julia Batki, Sara Hetzel, Dennis Schifferl, Adriano Bolondi, Maria Walther, Lars Wittler, Stefanie Grosswendt, Bernhard G. Herrmann, and Alexander Meissner, "Extraembryonic gut endoderm cells undergo programmed cell death during development," Nature Cell Biology 26 (6), 868-877 (2024).

Hannes Hauswedell , Sara Hetzel, Simon G. Gottlieb , Helene Kretzmer, Alexander Meissner, and Knut Reinert, "Lambda3: homology search for protein, nucleotide, and bisulfite-converted sequences," Bioinformatics 40 (3), Article btae097 (2024).

Marius-Konstantin Klever, Eric Sträng , Sara Hetzel, Julius Jungnitsch, Anna Dolnik, Robert Schöpflin, Jens-Florian Schrezenmeier, Felix Schick, Olga Blau, Jörg Westermann, Frank G . Rücker , Zuyao Xia, Konstanze Döhner, Hubert Schrezenmeier, Malte Spielmann, Alexander Meissner, Uirá Souto Melo, Stefan Mundlos, and Lars Bullinger, "AML with complex karyotype: extreme genomic complexity revealed by combined long-read sequencing and Hi-C technology," Blood Advances 7 (21), 6520-6531 (2023).

Raha Weigert, Sara Hetzel, Nina Bailly, Chuck Haggerty, Ibrahim A. Ilik, Philip Yuk Kwong Yung, Carmen Navarro, Adriano Bolondi, Abhishek Sampath Kumar, Chiara Anania, Björn Brändl, David Meierhofer, Darío G. Lupiáñez, Franz-Josef Müller, Tugce Aktas, Simon J. Elsässer, Helene Kretzmer, Zachary D. Smith, and Alexander Meissner, "Dynamic antagonism between key repressive pathways maintains the placental epigenome," Nature Cell Biology 25 (4), 579-591 (2023).

Alessa Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Juliane Glaser, Mai H. Q. Phan, Magdalena Schindler, Daniel M. Ibrahim, Christina Paliou, Andrea Esposito, César A. Prada-Medina, Stefan A. Haas, Peter Giere, Martin Vingron, Lars Wittler, Alexander Meissner, Mario Nicodemi, Giacomo Cavalli, Frédéric Bantignies, Stefan Mundlos, and Michael I. Robson, "Repression and 3D-restructuring resolves regulatory conflicts in evolutionarily rearranged genomes," Cell 185 (20), 3689-3704 (2022).

Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, Rene Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, and Denes Hnisz, "Hijacking of transcriptional condensates by endogenous retroviruses," Nature Genetics 54, 1238-1247 (2022).

Sara Hetzel, Alexandra L. Mattei, Helene Kretzmer, Chunxu Qu, Xiang Chen, Yiping Fan, Gang Wu, Kathryn G. Roberts, Selina Luger, Mark Litzow, Jacob Rowe, Elisabeth Paietta, Wendy Stock, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Charles G. Mullighan, and Alexander Meissner, "Acute lymphoblastic leukemia displays a distinct highly methylated genome," Nature Cancer 3 (6), 768-782 (2022).

Sara Hetzel, Pay Gießelmann, Knut Reinert, Alexander Meissner, and Helene Kretzmer, "RLM: Fast and simplified extraction of Read-Level Methylation metrics from bisulfite sequencing data," Bioinformatics 37 (21), 3934-3935 (2021).

Marlies P. Rossmann, Karen Hoi, Victoria Chan, Brian J. Abraham, Song Yang, James Mullahoo, Malvina Papanastasiou, Ying Wang, Ilaria Elia, Julie R. Perlin, Elliott J. Hagedorn, Sara Hetzel, Raha Weigert, Sejal Vyas, Partha P. Nag, Lucas B. Sullivan, Curtis R. Warren, Bilguujin Dorjsuren, Eugenia Custo Greig, Isaac Adatto, Chad A. Cowan, Stuart L. Schreiber, Richard A. Young, Alexander Meissner, Marcia C. Haigis, Siegfried Hekimi, Steven A. Carr, and Leonard I. Zon, "Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis," Science 372 (6543), 716-721 (2021).

Stefanie Grosswendt, Helene Kretzmer, Zachary D. Smith, Abhishek Sampath Kumar, Sara Hetzel, Lars Wittler, Sven Klages, Bernd Timmermann, Shankar Mukherji, and Alexander Meissner, "Epigenetic regulator function through mouse gastrulation," Nature 584, 102-108 (2020).

Pay Giesselmann, Sara Hetzel, Franz-Josef Müller, Alexander Meissner, and Helene Kretzmer, "Nanopype: A modular and scalable nanopore data processing pipeline," Bioinformatics 35 (22), 4770-4772 (2019).

Marius-Konstantin Klever, Eric Sträng, Julius Jungnitsch, Uirá Souto Melo, Sara Hetzel, Anna Dolnik, Robert Schöpflin, Jens F. Schrezenmeier, Olga Blau, Jörg Westermann, Konstanze Döhner, Hubert Schrezenmeier, Malte Spielmann, Alexander Meissner, Stefan Mundlos, and Lars Bullinger, "Integration of Hi-C and Nanopore Sequencing for Structural Variant Analysis in AML with a Complex Karyotype: (Chromothripsis)²", in Blood, (American Society of Hematology, Washington, DC, 2020), Vol. 136.

Marlies Rossmann, Karen Hoi, Victoria Chan, Brian Abraham, Song Yang, James Mullahoo, Malvina Papanastasiou, Ilaria Elia, Sejal Vyas, Partha Nag, Lucas Sullivan, Julie Perlin, Elliott Hagedorn, Sara Hetzel, Raha Weigert, Curtis Warren, Bilguujin Dorjsuren, Eugenia Custo Greig, Isaac Adatto, Chad Cowan, Stuart Schreiber, Richard Young, Alexander Meissner, Marcia Haigis, Steven Carr, and Leonard Zon, "Transcriptional regulation of mitochondrial metabolism by TIF1γ drives erythroid progenitor differentiation", in Experimental Hematology, (Elsevier, New York [etc.], 2020), Vol. 88.

Sara Hetzel, Investigation of DNA methylation heterogeneity in cancer, PhD Thesis, 2023.

Zachary D. Smith, Sara Hetzel, and Alexander Meissner, "DNA methylation in mammalian development and disease", in Nature Reviews Genetics, (Nature Pub. Group, London, UK, 2025), Vol. 26, pp. 7-30.

Alessa Ringel, Quentin Szabo, Andrea M. Chiariello, Konrad Chudzik, Robert Schöpflin, Patricia Rothe, Alexandra L. Mattei, Tobias Zehnder, Dermot Harnett, Verena Laupert, Simona Bianco, Sara Hetzel, Mai Phan, Magdalena Schindler, Daniel M. Ibrahim, Christina Paliou, Andrea Esposito, Cesar A. Prada-Medina, Stefan Haas, Peter Giere, Martin Vingron, Lars Wittler, Alexander Meissner, Mario Nicodemi, Giacomo Cavalli, Frédéric Bantignies, Stefan Mundlos, and Michael Robson, "Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs", in bioRxiv, (2021).