Publications of H. Lehrach

Mertes, F.; Elsharawy, A.; Sauer, S.; van Helvoort, J. M.; van der Zaag, P. J.; Franke, A.; Nilsson, M.; Lehrach, H.; Brookes, A. J.: Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics 10 (6), pp. 374 - 86 (2011)

Prigione, A.; Hossini, A. M.; Lichtner, B.; Serin, A.; Fauler, B.; Megges, M.; Lurz, R.; Lehrach, H.; Makrantonaki, E.; Zouboulis, C. C. et al.; Adjaye, J.: Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations. PLoS ONE 6 (11), p. e27352 (2011)

Prigione, A.; Lichtner, B.; Kuhl, H.; Struys, E. A.; Wamelink, M.; Lehrach, H.; Ralser, M.; Timmermann, B.; Adjaye, J.: Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Stem Cells 29 (9), pp. 1338 - 48 (2011)

Schjeide, B. M.; Schnack, C.; Lambert, J. C.; Lill, C. M.; Kirchheiner, J.; Tumani, H.; Otto, M.; Tanzi, R. E.; Lehrach, H.; Amouyel, P. et al.; von Arnim, C. A.; Bertram, L.: The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels. Archives of General Psychiatry 68 (2), pp. 207 - 13 (2011)

Schutze, T.; Rubelt, F.; Repkow, J.; Greiner, N.; Erdmann, V. A.; Lehrach, H.; Konthur, Z.; Glokler, J.: A streamlined protocol for emulsion polymerase chain reaction and subsequent purification. Analytical Biochemistry 410 (1), pp. 155 - 157 (2011)

Schutze, T.; Wilhelm, B.; Greiner, N.; Braun, H.; Peter, F.; Morl, M.; Erdmann, V. A.; Lehrach, H.; Konthur, Z.; Menger, M. et al.; Arndt, P. F.; Glokler, J.: Probing the SELEX Process with Next-Generation Sequencing. PLoS ONE 6 (12), p. e29604 - e29604 (2011)

Stehr, H.; Jang, S. H.; Duarte, J. M.; Wierling, C.; Lehrach, H.; Lappe, M.; Lange, B. M.: The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors. Molecular Cancer 10, p. 54 (2011)

Vilardell, M.; Rasche, A.; Thormann, A.; Maschke-Dutz, E.; Perez-Jurado, L. A.; Lehrach, H.; Herwig, R.: Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes. BMC Genomics 12, p. 229 (2011)

von Keyserling, H.; Bergmann, T.; Schuetz, M.; Schiller, U.; Stanke, J.; Hoffmann, C.; Schneider, A.; Lehrach, H.; Dahl, A.; Kaufmann, A. M.: Analysis of 4 single-nucleotide polymorphisms in relation to cervical dysplasia and cancer development using a high-throughput ligation-detection reaction procedure. International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society 21 (9), pp. 1664 - 71 (2011)

Warnatz, H. J.; Schmidt, D.; Manke, T.; Piccini, I.; Sultan, M.; Borodina, T.; Balzereit, D.; Wruck, W.; Soldatov, A.; Vingron, M. et al.; Lehrach, H.; Yaspo, M. L.: The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. The Journal of Biological Chemistry 286 (26), pp. 23521 - 32 (2011)

Timmermann, B.; Kerick, M.; Roehr, C.; Fischer, A.; Isau, M.; Boerno, S. T.; Wunderlich, A.; Barmeyer, C.; Seemann, P.; Koenig, J. et al.; Lappe, M.; Kuss, A. W.; Garshasbi, M.; Bertram, L.; Trappe, K.; Werber, M.; Herrmann, B. G.; Zatloukal, K.; Lehrach, H.; Schweiger, M. R.: Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS ONE 5 (12), p. e15661 - e15661 (2010)

Denoeud, F.; Henriet, S.; Mungpakdee, S.; Aury, J. M.; Da Silva, C.; Brinkmann, H.; Mikhaleva, J.; Olsen, L. C.; Jubin, C.; Canestro, C. et al.; Bouquet, J. M.; Danks, G.; Poulain, J.; Campsteijn, C.; Adamski, M.; Cross, I.; Yadetie, F.; Muffato, M.; Louis, A.; Butcher, S.; Tsagkogeorga, G.; Konrad, A.; Singh, S.; Jensen, M. F.; Cong, E. H.; Eikeseth-Otteraa, H.; Noel, B.; Anthouard, V.; Porcel, B. M.; Kachouri-Lafond, R.; Nishino, A.; Ugolini, M.; Chourrout, P.; Nishida, H.; Aasland, R.; Huzurbazar, S.; Westhof, E.; Delsuc, F.; Lehrach, H.; Reinhardt, R.; Weissenbach, J.; Roy, S. W.; Artiguenave, F.; Postlethwait, J. H.; Manak, J. R.; Thompson, E. M.; Jaillon, O.; Du Pasquier, L.; Boudinot, P.; Liberles, D. A.; Volff, J. N.; Philippe, H.; Lenhard, B.; Crollius, H. R.; Wincker, P.; Chourrout, D.: Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate. Science 330 (6009), pp. 1381 - 1385 (2010)

Wolfrum, K.; Wang, Y.; Prigione, A.; Sperling, K.; Lehrach, H.; Adjaye, J.: The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells. PLoS ONE 5 (10), p. e13703 - e13703 (2010)

Müller, H.; Schmidt, D.; Steinbrink, S.; Mirgorodskaya, E.; Lehmann, V.; Habermann, K.; Dreher, F.; Gustavsson, N.; Kessler, T.; Lehrach, H. et al.; Herwig, R.; Gobom, J.; Ploubidou, A.; Boutros, M.; Lange, B. M.: Proteomic and functional analysis of the mitotic Drosophila centrosome. The EMBO Journal 29 (19), pp. 3344 - 3357 (2010)

Warnatz, H. J.; Querfurth, R.; Guerasimova, A.; Cheng, X.; Haas, S. A.; Hufton, A. L.; Manke, T.; Vanhecke, D.; Nietfeld, W.; Vingron, M. et al.; Janitz, M.; Lehrach, H.; Yaspo, M. L.: Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters. Nucleic Acids Research 38 (18), pp. 6112 - 6123 (2010)

Mertes, F.; Biens, K.; Lehrach, H.; Wagner, M.; Dahl, A.: High-throughput Universal Probe Salmonella Serotyping (UPSS) by nanoPCR. J Microbiol Methods 83 (2), pp. 217 - 223 (2010)

Ungethuem, U.; Haeupl, T.; Witt, H.; Koczan, D.; Krenn, V.; Huber, H.; von Helversen, T. M.; Drungowski, M.; Seyfert, C.; Zacher, J. et al.; Pruss, A.; Neidel, J.; Lehrach, H.; Thiesen, H. J.; Ruiz, P.; Blaess, S.: Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis. Physiological Genomics 42A (4), pp. 267 - 282 (2010)

Chavez, L.; Jozefczuk, J.; Grimm, C.; Dietrich, J.; Timmermann, B.; Lehrach, H.; Herwig, R.; Adjaye, J.: Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Research 20, pp. 1441 - 1450 (2010)

Timmermann, B.; Jarolim, S.; Russmayer, H.; Kerick, M.; Michel, S.; Krüger, A.; Bluemlein, K.; Laun, P.; Grillari, J.; Lehrach, H. et al.; Breitenbach, M.; Ralser, M.: A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. Aging (Albany NY) 2 (8), pp. 475 - 486 (2010)

Dahl, A.; Mertes, F.; Timmermann, B.; Lehrach, H.: The application of massively parallel sequencing technologies in diagnostics. F1000 Biology Reports 2, p. 2:59 - 2:59 (2010)