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Journal Article (117)

1.
Journal Article
Farrall, A.; Lienhard, M.; Grimm, C.; Kuhl, H.; Sluka, S. H. M.; Caparros Rodriguez, M.; Forejt, J.; Timmermann, B.; Herwig, R.; Herrmann, B. G. et al.; Morkel, M.: PWD/Ph-encoded genetic variants modulate the cellular Wnt/β-Catenin response to suppress ApcMin-triggered intestinal tumor formation. Cancer research: an official organ of the American Association for Cancer Research 81 (1), pp. 38 - 49 (2021)
2.
Journal Article
Veenvliet, J. V.; Bolondi, A.; Kretzmer, H.; Haut, L.; Scholze-Wittler, M.; Schifferl, D.; Koch, F.; Guignard, L.; Sampath Kumar, A.; Pustet, M. et al.; Heimann, S.; Buschow, R.; Wittler, L.; Timmermann, B.; Meissner, A.; Herrmann, B. G.: Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. Science 370 (6522), eaba4937 (2020)
3.
Journal Article
Kretzmer, H.; Biran, A.; Purroy, N.; Lemvigh, C. K.; Clement, K.; Gruber, M.; Gu, H.; Rassenti, L.; Mohammad, A. W.; Lesnick, C. et al.; Slager, S. L.; Braggio, E.; Shanafelt, T. D.; Kay, N. E.; Fernandes, S. M.; Brown, J. R.; Wang, L.; Li, S.; Livak, K. J.; Neuberg, D. S.; Klages, S.; Timmermann, B.; Kipps, T. J.; Campo, E.; Gnirke, A.; Wu, C. J.; Meissner, A.: Pre-neoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood Cancer Discovery 2021, 2:1–16 (2020)
4.
Journal Article
Xiao, Y.; Rabien, A.; Buschow, R.; Amstislavskiy, V.; Busch, J.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Schütte, M.; Mielke, T. et al.; Yaspo, M.-L.; Jung, K.; Meierhofer, D.: Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research 2020 (2020)
5.
Journal Article
Wei, X.; Franke, J.; Ost, M.; Wardelmann, K.; Börno, S.; Timmermann, B.; Meierhofer, D.; Kleinridders, A.; Klaus, S.; Stricker, S.: Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis. Journal of Cachexia, Sarcopenia and Muscle 2020, 12632 (2020)
6.
Journal Article
Selevsek, N.; Caiment, F.; Nudischer, R.; Gmuender, H.; Agarkova, I.; Atkinson, F. L.; Bachmann, I.; Baier, V.; Barel, G.; Bauer, C. et al.; Boerno, S.; Bosc, N.; Clayton, O.; Cordes, H.; Deeb, S.; Gotta, S.; Guye, P.; Hersey, A.; Hunter, F. M. I.; Kunz, L.; Lewalle, A.; Lienhard, M.; Merken, J.; Minguet, J.; Oliveira, B.; Pluess, C.; Sarkans, U.; Schrooders, Y.; Schuchhardt, J.; Smit, I.; Thiel, C.; Timmermann, B.; Verheijen, M.; Wittenberger, T.; Wolski, W.; Zerck, A.; Heymans, S.; Kuepfer, L.; Roth, A.; Schlapbach, R.; Niederer, S.; Herwig, R.; Kleinjans, J.: Network integration and modelling of dynamic drug responses at multi-omics levels. Communications Biology 3, 573 (2020)
7.
Journal Article
Real, F. M.; Haas, S. A.; Franchini, P.; Xiong, P.; Simakov, O.; Kuhl, H.; Schöpflin, R.; Heller, D.; Moeinzadeh, M. H.; Heinrich, V. et al.; Krannich , T.; Bressin, A.; Hartmann, M. F.; Wudy, S. A.; Dechmann, D. K. N.; Hurtado, A.; Barrionuevo, F. J.; Schindler, M.; Harabula, I.; Osterwalder, M.; Hiller, M.; Wittler, L.; Visel, A.; Timmermann, B.; Meyer, A.; Vingron, M.; Jiménez, R.; Mundlos, S.; Lupiáñez, D. G.: The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. Science 370 (6513), pp. 208 - 214 (2020)
8.
Journal Article
Smajic, S.; Prada-Medina, C. A.; Landoulsi, Z.; Dietrich, C.; Jarazo, J.; Henck, J.; Balachandran, S.; Pachchek, S.; Morris, C. M.; Anthony, P. et al.; Timmermann, B.; Sauer, S.; Schwamborn, J. C.; May, P.; Grunewald, A.; Spielmann, M.: Single-cell sequencing of the human midbrain reveals glial activation and a neuronal state specific to Parkinson's disease. medRxiv (The Preprint Server for health sciences.) (2020)
9.
Journal Article
Grosswendt, S.; Kretzmer, H.; Smith, Z. D.; Sampath Kumar, A.; Hetzel, S.; Wittler, L.; Klages, S.; Timmermann, B.; Mukherji, S.; Meissner, A.: Epigenetic regulator function through mouse gastrulation. Nature 584, pp. 102 - 108 (2020)
10.
Journal Article
Xiao, Y.; Clima, R.; Busch, J.; Rabien, A.; Kilic, E.; Villegas, S. L.; Timmermann, B.; Attimonelli, M.; Jung, K.; Meierhofer, D.: Decreased mitochondrial DNA content drives OXPHOS dysregulation in chromophobe renal cell carcinoma. Cancer research: an official organ of the American Association for Cancer Research, CAN-20-0754 (2020)
11.
Journal Article
Bratovič, M.; Fonfara, I.; Chylinski, K.; Gálvez, E. J. C.; Sullivan, T. J.; Boerno, S.; Timmermann, B.; Boettcher, M.; Charpentier, E.: Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches. Nature Chemical Biology 2020 (2020)
12.
Journal Article
Herdt, O.; Reich, S.; Medenbach, J.; Timmermann, B.; Olofsson, D.; Preußner, M.; Heyd, F.: The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation. RNA Biology 2020 (2020)
13.
Journal Article
Haltenhof, T.; Kotte, A.; De Bortoli, F.; Schiefer, S.; Meinke, S.; Emmerichs, A.-K.; Petermann, K. K.; Timmermann, B.; Imhof, P.; Franz, A. et al.; Loll, B.; Wahl, M. C.; Preußner, M.; Heyd , F.: A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Molecular Cell 2020 (2020)
14.
Journal Article
Kupke, S. Y.; Ly, L.-H.; Börno, S. T.; Ruff, A.; Timmermann, B.; Vingron, M.; Haas, S.: Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses 12 (1), pii: E71 (2020)
15.
Journal Article
Alahmad, A.; Paffrath, V.; Clima, R.; Busch, J. F.; Rabien, A.; Kilic, E.; Villegas, S.; Timmermann, B.; Attimonelli, M.; Jung, K. et al.; Meierhofer, D.: Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation. Cancers 11 (9), 1298 (2019)
16.
Journal Article
Segal, J.; Mülleder, M.; Krüger, A.; Adler, T.; Scholze-Wittler, M.; Becker, L.; Calzada-Wack, J.; Garrett, L.; Hölter, S. M.; Rathkolb, B. et al.; Rozman, J.; Racz, I.; Fischer, R.; Busch, D. H.; Neff, F.; Klingenspor, M.; Klopstock, T.; Grüning, N.-M.; Michel, S.; Lukaszewska-McGreal, B.; Voigt, I.; Hartmann, L.; Timmermann, B.; Lehrach, H.; Wolf, E.; Wurst, W.; Gailus-Durner, V.; Fuchs, H.; de Angelis, M. H.; Schrewe, H.; Yuneva, M.; Ralser, M.: Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase (TPI) deficiency. Journal of Inherited Metabolic Disease 22 (5), pp. 839 - 849 (2019)
17.
Journal Article
Bose, D.; Neumann, A.; Timmermann, B.; Meinke, S.; Heyd, F.: Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation. Molecular and Cellular Biology (Washington, DC) 39 (16), e00035-19 (2019)
18.
Journal Article
Despang, A.; Schöpflin, R.; Franke, M.; Ali, S.; Jerković, I.; Paliou, C.; Chan, W.-L.; Timmermann, B.; Wittler, L.; Vingron, M. et al.; Mundlos, S.; Ibrahim, D. M.: Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture. Nature Genetics 51 (8), pp. 1263 - 1271 (2019)
19.
Journal Article
Fattahi, Z.; Beheshtian, M.; Mohseni, M.; Poustchi, H.; Sellars, E.; Nezhadi, S. H.; Amini, A.; Arzhangi, S.; Jalalvand, K.; Jamali, P. et al.; Mohammadi, Z.; Davarnia, B.; Nikuei, P.; Oladnabi, M.; Mohammadzadeh, A.; Zohrehvand, E.; Nejatizadeh, A.; Shekari, M.; Bagherzadeh, M.; Shamsi‐Gooshki, E.; Börno, S.; Timmermann, B.; Haghdoost, A.; Najafipour, R.; Khorram Khorshid, H. R.; Kahrizi, K.; Malekzadeh, R.; Akbari, M. R.; Najmabadi, H.: Iranome: A catalogue of genomic variations in the Iranian population. Human Mutation 2019, pp. 1 - 17 (2019)
20.
Journal Article
Hu, H.; Kahrizi, K.; Musante, L.; Fattahi, Z.; Herwig, R.; Hosseini, M.; Oppitz, C.; Abedini, S. S.; Suckow, V.; Farzaneh, L. et al.; Beheshtian, M.; Lipkowitz, B.; Akhtarkhavari, T.; Mehvari, S.; Otto, S.; Mohseni, M.; Arzhangi, S.; Jamali, P.; Mojahedi, F.; Taghdiri, M.; Papari, E.; Soltani Banavandi, M. J.; Akbari, S.; Tonekaboni, S. H.; Dehghani, H.; Ebrahimpou, M. R.; Bader, I.; Davarnia, B.; Cohen, M.; Khodaei, H.; Albrecht, B.; Azimi, S.; Zirn, B.; Bastami, M.; Wieczorek, D.; Bahrami, G.; Keleman, K.; Vahid, L. N.; Timmermann, B.; Pourfatemi, F.; Jankhah, A.; Chen, W.; Nikuei, P.; Kalscheuer, V. M.; Oladnabi, M.; Wienker, T. F.; Ropers, H.-H.; Najmabadi, H.: Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 24 (7), pp. 1027 - 1039 (2019)
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