All Publications
The following publications were published exclusively under the affiliation of the Max Planck Society. For publications by the principal investigator outside of the Max Planck Society, see the links on the lower left.
Publication by Hnisz Lab
Preprints
2022
Androgen receptor condensates as drug targets. bioRxiv (2022)
Published
2025
Probing condensate microenvironments with a micropeptide killswitch. Nature (2025)
2024
26 (8), pp. 1309 - 1321 (2024)
An activity-specificity trade-off encoded in human transcription factors. Nature Cell Biology 2023
30 (12), pp. 1958 - 1969 (2023)
Rational optimization of a transcription factor activation domain inhibitor. Nature Structural & Molecular Biology 14 (1), Article 4971 (2023)
High-sensitive nascent transcript sequencing reveals BRD4-specific control of widespread enhancer and target gene transcription. Nature Communications 42 (8), 112897 (2023)
CEBPA phase separation links transcriptional activity and 3D chromatin hubs. Cell Reports 42 (5), 112505 (2023)
Regulatory architecture of housekeeping genes is driven by promoter assemblies. Cell Reports 614 (7948), pp. 564 - 571 (2023)
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases. Nature 12, Article e83077 (2023)
T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation. eLife 2022
54 (8), pp. 1238 - 1247 (2022)
Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 2021
39 (6), pp. 827 - 844 (2021)
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma. Cancer Cell 2020
52 (7), pp. 719 - 727 (2020)
Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics 181 (5), pp. 1062 - 1079 (2020)
Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. Cell 2018
Coactivator condensation at super-enhancers links phase separation and gene control. Science (6400), eaar3958 (2018)
23 (2), pp. 349 - 360 (2018)
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism. Cell Reports Publications by Dr. Denes Hnisz before 2018
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Cell, Volume 171, Issue 7, 2017
New Insights into Genome Structure: Genes of a Feather Stick Together
Molecular Cell, Volume 67, Issue 5, 2017
A Phase Separation Model for Transcriptional Control
Cell, Volume 169, Issue 1, 2017
Small genomic insertions form enhancers that misregulate oncogenes
Nature Communications volume 8, 2017
Transcriptional Addiction in Cancer
Cell, Volume 168, Issue 4, 2017
Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control
Cell, Volume 167, Issue 5, 2016
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
Nature Genetics volume 48, 2016
Activation of proto-oncogenes by disruption of chromosome
Science Vol.351, 2016
3D Chromosome Regulatory Landscape of Human Pluripotent Cells
Cell Stem Cell, Volume 18, Issue 2, 2016
Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers
Molecular Cell, Volume 58, Issue 2, 2015