Our work together with the Marsico lab, where we use machine learning to identify the rules of Xist-mediated gene silencing was published in Genome Research.
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features.
Genome Res. 2019 Jun 7. pii: gr.245027.118. [Epub ahead of print]
First mathematical model of Xist regulatory network published. See press release
A symmetric toggle switch explains the onset of random X inactivation in different mammals.
Nature Structural and Molecular Biology 2019 May;26(5):350-360. Epub 2019 Apr 8.