Lab News

Our work together with the Marsico lab, where we use machine learning to identify the rules of Xist-mediated gene silencing was published in Genome Research.
1.
Barros de Andrade E Sousa L, Jonkers I, Syx L, Dunkel I, Chaumeil J, Picard C, Foret B, Chen CJ, Lis JT, Heard E, Schulz EG, Marsico A.
Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features.
Genome Res. 2019 Jun 7. pii: gr.245027.118. [Epub ahead of print]

First mathematical model of Xist regulatory network published. See press release
2.
Mutzel V, Okamoto I, Dunkel I, Saitou M, Giorgetti L, Heard E, Schulz EG
A symmetric toggle switch explains the onset of random X inactivation in different mammals.
Nature Structural and Molecular Biology 2019 May;26(5):350-360. Epub 2019 Apr 8.

Welche Geheimnisse haben X-Chromosomen? - Berlin - #wonachsuchstdu

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