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Documentary on gender medicine - 08.03.2023

Documentary on gender medicine - 08.03.2023

Some time back, a german film team visited us for a documentary on gender medicine. It's now online, we are in the first part :
Register now ! - 01.03.2023

Register now ! - 01.03.2023


5th X-inactivation meeting (EMBO)
19-22 June 2023, in Berlin

Registration deadline: 01 April 2023.
25 talks selected from abstracts.
Anniversary for Ilona - 01.02.2023

Anniversary for Ilona - 01.02.2023

Ilona celebrates her 40-year anniversary of working at this institute! We are very grateful to have her on our team, managing the lab and doing the most challenging experiments!
Rafael visits - 15.01.2023

Rafael visits - 15.01.2023

Rafael Galupa will stay with us for two months to do several CRISPR screens. Welcome!
 
Jonathan joins - 04.01.2023

Jonathan joins - 04.01.2023

Jonathan Froehlich joins the team as a Postdoc. Welcome!
 
Poster prize for Nelly - 02.12.2022

Poster prize for Nelly - 02.12.2022

Our Nelly Kanata won a poster prize at the 2022 Max Planck Freiburg Epigenetics Meeting. Congratulations @nellykanata !
 
PhD program recruitment - 11.11.2022

PhD program recruitment - 11.11.2022

The new round of PhD program recruitment is open, deadline is January 6th, 2023.Our lab proposes two potential projects. One to study how different levels in gene regulatory factors affect cellular decision. The second to study how gene regulatory DNA affects cell-to-cell heterogeneity in transcriptional responses. Both projects will be relevant to better understand gene regulation and cell fate; using CRISPR tools, genomic profiling techniques, and relevant computational analysis.
Preprint - 06.10.2022

Preprint - 06.10.2022

We present CasTuner, a CRISPR-based toolkit that allows analog tuning of endogenous gene expression.
  • CasTuner: a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression. Noviello G, Rutger RAF, and Schulz EG. BioRxiv 2022
  • Edda & Gemma's tweetorial
Attending Freiburg Epigenetics Meeting - 01.10.2022

Attending Freiburg Epigenetics Meeting - 01.10.2022

Nelly will attend the “Max Planck Freiburg 6th Epigenetics Meeting”
30 Nov – 02 Dec 2022
Reach out to Nelly Kanata!
https://events.ie-freiburg.mpg.de/3161/1About_the_conference

 
Attending EMBL Systems Biology Meeting - 01.09.2022

Attending EMBL Systems Biology Meeting - 01.09.2022

Till will attend “EMBO - From functional genomics to systems biology”
15 - 18 Nov 2022
Reach out to Till Schwämmle!
https://www.embl.org/about/info/course-and-conference-office/events/omx22-01/
 
Publication - 20.12.2021

Publication - 20.12.2021

We scanned the regulatory landscape of Xist and found several proximal and distal enhancers, as well as a new ncRNA Xert, that all control X-inactivation.
  • Distal and proximal cis-regulatory elements sense X-chromosomal dosage and developmental state at the Xist locus. Gjaltema RAF*, Schwämmle T*, Kautz P, Robson M, Schöpflin R, Lustig LR, Brandenburg L, Dunkel I, Vechiatto C, Ntini E, Mutzel V, Schmiedel V, Marsico A, Mundlos S, Schulz EG. Molecular Cell 2021
  • Preview by Elphège Nora here.
  • Institute’s press release here.
EMBO Young Investigator award for Edda - 08.12.2021

EMBO Young Investigator award for Edda - 08.12.2021

Edda has been accepted by the European Molecular Biology Organization (EMBO) into its Young Investigators Programme. Every year, the organization honors the most promising young researchers in Europe.
  • Institute’s press release here.

 

 

 

...ups, we lost some records here :( please have patience - we are working on recovering them...

 

 

 

Publication - 07.06.2019

Publication - 07.06.2019

Our work together with the Marsico lab, where we use machine learning to identify the rules of Xist-mediated gene silencing was published:
  • Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features. Barros de Andrade E Sousa L, Jonkers I, Syx L, Dunkel I, Chaumeil J, Picard C, Foret B, Chen CJ, Lis JT, Heard E, Schulz EG, Marsico A. Genome Res. 2019
Publication - 08.04.2019

Publication - 08.04.2019

First mathematical model of Xist regulatory network published. See press release
Youtuber Dr Watson visited us - 21.08.2018

Youtuber Dr Watson visited us - 21.08.2018

As part of the "Max Planck Day" we got a visit from the Youtuber Dr Watson to explain our work on X inactivation.
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