Selected Publications
Our top publications
25 (11), pp. 1704 - 1715 (2023)
GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Nature Cell Biology
14 (1), 3225 (2023)
CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression. Nature Communications
19 (11), e11510 (2023)
Modeling unveils sex differences of signaling networks in mouse embryonic stem cells. Molecular Systems Biology
82 (1), pp. 190 - 208 (2022)
Distal and proximal cis-regulatory elements sense X-chromosomal dosage and developmental state at the Xist locus. Molecular Cell
12 (1), 3638 (2021)
Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution. Nature Communications
22, 110 (2021)
Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach. Genome Biology
26 (5), pp. 350 - 360 (2019)
A symmetric toggle switch explains the onset of random X inactivation in different mammals. Nature Structural and Molecular Biology