Zeitschriftenartikel (155)

101.
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Brumbaugh , J.; Kim, I. S.; Ji, F.; Huebner, A. J.; Di Stefano , B.; Schwarz, B. A.; Charlton, J.; Coffey, A.; Choi, J.; Walsh, R. M. et al.; Schindler, J. W.; Anselmo, A.; Meissner, A.; Sadreyev, R. I.; Bernstein, B. E.; Hock, H.; Hochedlinger , K.: Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology 21 (11), S. 1449 - 1461 (2019)
102.
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Thakurela, S.; Sindhu, C.; Yurkovsky, E.; Riemenschneider, C.; Smith, Z. D.; Nachman, I.; Meissner, A.: Differential regulation of OCT4 targets facilitates reacquisition of pluripotency. Nature Communications 10, 4444 (2019)
103.
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Tsankov, A. M.; Wadsworth, M. H.; Akopian, V.; Charlton, J.; Allon, S. J.; Arczewska, A. A.; Mead, B. E.; Drake, R. S.; Smith, Z. D.; Mikkelsen, T. S. et al.; Shalek, A. K.; Meissner, A.: Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development 146 (19), dev174722 (2019)
104.
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Jönsson, M. E.; Brattas, P. L.; Gustafsson, C.; Petri, R.; Yudovich, D.; Pircs, K.; Verschuere, S.; Madsen, S.; Hansson, J.; Larsson, J. et al.; Mansson, R.; Meissner, A.; Jakobsson, J.: Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nature Communications 10, 3182 (2019)
105.
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Hu, H.; Kahrizi, K.; Musante, L.; Fattahi, Z.; Herwig, R.; Hosseini, M.; Oppitz, C.; Abedini, S. S.; Suckow, V.; Farzaneh, L. et al.; Beheshtian, M.; Lipkowitz, B.; Akhtarkhavari, T.; Mehvari, S.; Otto, S.; Mohseni, M.; Arzhangi, S.; Jamali, P.; Mojahedi, F.; Taghdiri, M.; Papari, E.; Soltani Banavandi, M. J.; Akbari, S.; Tonekaboni, S. H.; Dehghani, H.; Ebrahimpou, M. R.; Bader, I.; Davarnia, B.; Cohen, M.; Khodaei, H.; Albrecht, B.; Azimi, S.; Zirn, B.; Bastami, M.; Wieczorek, D.; Bahrami, G.; Keleman, K.; Vahid, L. N.; Timmermann, B.; Pourfatemi, F.; Jankhah, A.; Chen, W.; Nikuei, P.; Kalscheuer, V. M.; Oladnabi, M.; Wienker, T. F.; Ropers, H.-H.; Najmabadi, H.: Genetics of intellectual disability in consanguineous families. Molecular Psychiatry 24 (7), S. 1027 - 1039 (2019)
106.
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Giesselmann, P.; Hetzel, S.; Müller, F.-J.; Meissner, A.; Kretzmer, H.: Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 35 (22), S. 4770 - 4772 (2019)
107.
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Modic, M.; Grosch, M.; Rot, G.; Schirge, S.; Lepko, T.; Yamazaki, T.; Lee, F. C. Y.; Rusha, E.; Shaposhnikov, D.; Palo, M. et al.; Merl-Pham, J.; Cacchiarelli, D.; Rogelj, B.; Hauck, S. M.; von Mering, C.; Meissner, A.; Lickert, H.; Hirose, T.; Drukker, M.: Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell 74 (5), S. 951 - 965 (2019)
108.
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Chan, M. M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T. M.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Jones, M. G. et al.; Khodaverdian, A.; Nir, Y.; Meissner, A.; Weissman, J. S.: Molecular recording of mammalian Embryogenesis. Nature 570 (7759), S. 77 - 82 (2019)
109.
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Gaiti, F.; Chaligne, R.; Gu, H.; Brand, R. M.; Kothen-Hill, S.; Schulman, R. C.; Grigorev, K.; Risso, D.; Kim, K.-T.; Pastore, A. et al.; Huang, K. Y.; Alonso, A.; Sheridan, C.; Omans, N. D.; Biederstedt, E.; Clement, K.; Wang, L.; Felsenfeld, J. A.; Bhavsar, E. B.; Aryee, M. J.; Allan, J. N.; Furman, R.; Gnirke, A.; Wu, C. J.; Meissner, A.; Landau, D. A.: Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 569 (7757), S. 576 - 580 (2019)
110.
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Pastore, A.; Gaiti, F.; Lu, S. X.; Brand, R. M.; Kulm, S.; Chaligne, R.; Gu, H.; Huang, K. Y.; Stamenova, E. K.; Béguelin, W. et al.; Jiang, Y.; Chulman, R. C.; Kim, K.-T.; Alonso, A.; Allan, J. N.; Furman, R. R.; Gnirke, A.; Wu, C. J.; Melnick, A. M.; Meissner, A.; Bernstein, B. E.; Abdel-Wahab, O.; Landau, D. A.: Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications 10 (1), 1874 (2019)
111.
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Kraft, K.; Magg, A.; Heinrich, V.; Riemenschneider, C.; Schöpflin, R.; Markowski, J.; Ibrahim, D.; Acuna-Hidalgo, R.; Despang, A.; Andrey, G. et al.; Wittler, L.; Timmermann, B.; Vingron, M.; Mundlos, S.: Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations. Nature Cell Biology 21 (3), S. 305 - 310 (2019)
112.
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Krols, M.; Asselbergh, B.; De Rycke, R.; De Winter, V.; Seyer, A.; Müller, F.-J.; Kurth, I.; Bultynck, G.; Timmerman, V.; Janssens, S.: Sensory neuropathy-causing mutations in ATL3 affect ER-mitochondria contact sites and impair axonal mitochondrial distribution. Human Molecular Genetics 28 (4), S. 615 - 627 (2019)
113.
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Hinohara, K.; Wu, H.-J.; Vigneau, S.; McDonald, T. O.; Igarashi, K. J.; Yamamoto, K. N.; Madsen, T.; Fassl, A.; Egri, S. B.; Papanastasiou, M. et al.; Ding, L.; Peluffo, G.; Cohen, O.; Kales, S. C.; Lal-Nag, M.; Rai, G.; Maloney, D. J.; Jadhav, A.; Simeonov, A.; Wagle, N.; Brown, M.; Meissner, A.; Sicinski, P.; Jaffe, J. D.; Jeselsohn, R.; Gimelbrant, A. A.; Michor, F.; Polyak, K.: KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell 35 (2), S. 330 - 332 (2019)
114.
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Klein, H.-U.; McCabe, C.; Gjoneska, E.; Sullivan, S. E.; Kaskow, B. J.; Tang, A.; Smith, R. V.; Xu, J.; Pfenning, A. R.; Bernstein, B. E. et al.; Meissner, A.; Schneider, J. A.; Mostafavi, S.; Tsai, L.-H.; Young-Pearse, T. L.; Bennett, D. A.; De Jager, P. L.: Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience 22 (1), S. 37 - 46 (2019)
115.
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Neureiter, A.; Brändl, B.; Hiber, M.; Tandon, R.; Müller, F.-J.; Steenpass, L.: Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect. Stem Cell Research 33, S. 20 - 24 (2018)
116.
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Tandon, R.; Brändl, B.; Baryshnikova, N.; Landshammer, A.; Steenpaß, L.; Keminer, O.; Pless, O.; Müller, F.-J.: Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Research 33, S. 120 - 124 (2018)
117.
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Zhang, Y.; Charlton, J.; Karnik, R.; Beerman, I.; Smith, Z. D.; Gu, H.; Boyle, P.; Mi , X.; Clement, K.; Pop, R. et al.; Gnirke, A.; Rossi, D. J.; Meissner, A.: Targets and genomic constraints of ectopic Dnmt3b expression. eLife 7, e40757 (2018)
118.
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Ichida, J. K.; Staats, K. A.; Davis-Dusenbery, B. N.; Clement, K.; Galloway, K. E.; Babos, K. N.; Shi, Y.; Son, E. Y.; Kiskinis, E.; Atwater, N. et al.; Gu, H.; Gnirke, A.; Meissner, A.; Eggan, K.: Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons. Development 145 (22), pii: dev168617 (2018)
119.
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Bernstein, E.; Meissner, A.; Ramalho-Santos, M.: Paying PIs from grants blocks talent and diversity. Nature 563 (7731), S. 325 (2018)
120.
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Rajavelu, A.; Lungu, C.; Emperle, M.; Dukatz, M.; Bröhm, A.; Broche, J.; Hanelt, I.; Parsa, E.; Schiffers, S.; Karnik, R. et al.; Meissner, A.; Carell, T.; Rathert, P.; Jurkowska, R. Z.; Jeltsch, A.: Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2. Nucleic Acids Research (London) 46 (17), S. 9044 - 9056 (2018)
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