Publications of the Chung lab

Sahu, A.; Li, N.; Dunkel, I.; Chung, H.-R.: EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications. Epigenetics & Chromatin 13 (1), Article 20 (2020)

Grunert, M.; Appelt, S.; Dunkel, I.; Berger, F.; Sperling, S. R.: Altered microRNA and target gene expression related to Tetralogy of Fallot. Scientific Reports 9 (1), 19063 (2019)

Lam, K. C.; Chung, H.-R.; Semplicio, G.; Iyer, S. S.; Gaub, A.; Bhardwaj, V.; Holz, H.; Georgiev, P.; Akhtar, A.: The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise. Genes and Development 33 (7-8), pp. 452 - 465 (2019)

van Bömmel, A.; Love, M. I.; Chung, H.-R.; Vingron, M.: coTRaCTE predicts co-occurring transcription factors within cell-type specific enhancers. PLoS Computational Biology 14 (8), e1006372 (2018)

Thormann, V.; Rothkegel, M. C.; Schöpflin, R.; Glaser, L. V.; Djuric, P.; Li, N.; Chung, H.-R.; Schwahn, K.; Vingron, M.; Meijsing, S.: Genomic dissection of enhancers uncovers principles of combinatorial regulation and dynamic wiring of enhancer-promoter contacts. Nucleic Acids Research (London) 46 (6), pp. 2868 - 2882 (2018)

Bhat, J.; Helmuth, J.; Chitadze, G.; Kouakanou, L.; Peters, C.; Vingron, M.; Ammerpohl, O.; Kabelitz, D.: Stochastics of Cellular Differentiation Explained by Epigenetics: The Case of T-Cell Differentiation and Functional Plasticity. Scand J Immunol 86 (4), pp. 184 - 195 (2017)

Yang, J.; Moeinzadeh, M. H.; Kuhl, H.; Helmuth, J.; Xiao, P.; Haas, S.; Liu, G.; Zheng, J.; Sun, Z.; Fan, W. et al.; Deng, G.; Wang, H.; Hu, F.; Zhao, S.; Fernie, A. R.; Börno, S. T.; Timmermann, B.; Zhang, P.; Vingron, M.: Haplotype-resolved sweet potato genome traces back its hexaploidization history. Nature Plants 2017 (3), pp. 696 - 703 (2017)

Fuchs, A.; Torroba, M.; Kinkley, S.: PHF13: A new player involved in RNA polymerase II transcriptional regulation and co-transcriptional splicing. Transcription 8 (2), pp. 106 - 112 (2017)

Kinkley, S.; Helmuth, J.; Polansky, J. K.; Dunkel, I.; Gasparoni, G.; Fröhler, S.; Chen, W.; Walter, J.; Hamann, A.; Chung, H.-R.: reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4+ memory T-Cells. Nature Communications 7, 7:12514 (2016)

Chung, H.-R.; Xu, C.; Fuchs, A.; Mund, A.; Lange, M.; Staege, H.; Schubert, T.; Bian, C.; Dunkel, I.; Eberharter, A. et al.; Regnard, C.; Klinker, H.; Meierhofer, D.; Cozzuto, L.; Winterpracht, A.; Di Croce, L.; Min, J.; Will, H.; Kinkley, S.: PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. eLife 5, 5:e10607 (2016)

Juan, D.; Perner, J.; Carrillo de Santa Pau, E.; Marsili, S.; Ochoa, D.; Chung, H. R.; Vingron, M.; Rico, D.; Valencia, A.: Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs. Cell Reports 14 (5), pp. 1246 - 1257 (2016)

Reiter, C.; Heise, F.; Chung, H.-R.; Ehrenhofer-Murray, A. E.: A link between Sas2-mediated H4 K16 acetylation, chromatin assembly in S-phase by CAF-I and Asf1, and nucleosome assembly by Spt6 during transcription. FEMS Yeast Research 15 (7), fov073 (2015)

Ramirez, F.; Lingg, T.; Toscano, S.; Lam, K. C.; Georgiev, P.; Chung, H. R.; Lajoie, B. R.; de Wit, E.; Zhan, Y.; de Laat, W. et al.; Dekker, J.; Manke, T.; Akhtar, A.: High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila. Molecular Cell 60 (1), pp. 146 - 162 (2015)

Eduati, F.; Mangravite, L. M.; Wang, T.; Tang, H.; Bare, J. C.; Huang, R.; Norman, T.; Kellen, M.; Menden, M. P.; Yang, J. et al.; Zhan, X.; Zhong, R.; Xiao, G.; Xia, M.; Abdo, N.; Kosyk, O.; Collaboration, N.-N.-U. D. T.; van Bömmel, A.; Caffrey, B.; Heinig, M.; Huska, M.; Mammana, A.; Perner, J.; Vingron, M.; Friend, S.; Dearry, A.; Simeonov, A.; Tice, R. R.; Rusyn, I.; Wright, F. A.; Stolovitzky, G.; Xie, Y.; Saez-Rodriguez, J.: Prediction of human population responses to toxic compounds by a collaborative competition. Nat Biotechnol 33 (9), pp. 933 - 940 (2015)

Starick, S. R.; Ibn-Salem, J.; Jurk, M.; Hernandez, C.; Love, M. I.; Chung, H.-R.; Vingron, M.; Thomas-Chollier, M.; Meijsing, S. H.: ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors. Genome Res 25 (6), pp. 825 - 835 (2015)

Mammana, A.; Chung, H.-R.: Chromatin segmentation based on a probabilistic model for read counts explains a large portion of the epigenome. Genome Biology 16, 16:151 (2015)

Perner, J.; Lasserre, J.; Kinkley, S.; Vingron, M.; Chung, H.-R.: Inference of interactions between chromatin modifiers and histone modifications: from ChIP-Seq data to chromatin-signaling. Nucleic Acids Research (London) 42 (22), pp. 13689 - 13695 (2014)

Ibn-Salem, J.; Köhler, S.; Love, M. I.; Chung, H.-R.; Huang, N.; Hurles, M. E.; Haendel, M.; Washington, N. L.; Smedley, D.; Mungall, C. J. et al.; Lewis, S. E.; Ott, C. E.; Bauer, S.; Schofield, P. N.; Mundlos, S.; Spielmann, M.; Robinson, P. N.: Deletions of chromosomal regulatory boundaries are associated with congenital disease. Genome Biology: Biology for the Post-Genomic Era 15, 15:423 (2014)

Cui, H.; Schlesinger, J.; Bansal, V.; Dunkel, I.; Meierhofer, D.; Rickert-Sperling, S.: 5Regulation of myogenesis via kinase driven activation of DPF3a, a BAF complex member and its interaction with transcription repressor HEY1. Cardiovascular Research 103 (Suppl 1), S 1 (2014)

Grunert, M.; Dorn, C.; Schueler, M.; Dunkel, I.; Schlesinger, J.; Mebus, S.; Alexi-Meskishvili, V.; Perrot, A.; Wassilew, K.; Timmermann, B. et al.; Hetzer, R.; Berger, F.; Sperling, S. R.: Rare and Private Variations in Neural Crest, Apoptosis and Sarcomere Genes Define the Polygenic Background of Isolated Tetralogy of Fallot. Human Molecular Genetics 23 (12), pp. 3115 - 3128 (2014)