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Journal Article (10)

  1. 1.
    Journal Article
    Wruck, W.; Kashofer, K.; Rehman, S.; Daskalaki, A.; Berg, D.; Gralka, E.; Jozefczuk, J.; Drews, K.; Pandey, V.; Regenbrecht, C. et al.; Wierling, C. K.; Turano, P.; Korf, U.; Zatloukal, K.; Lehrach, H.; Westerhoff, H. V.; Adjaye, J.: Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes. Scientific Data 2 (2015)
  2. 2.
    Journal Article
    Moschidou, D.; Mukherjee, S.; Blundell, M. P.; Drews, K.; Jones, G. N.; Abdulrazzak, H.; Nowakowska, B.; Phoolchund, A.; Lay, K.; Ramasamy, T. S. et al.; Cananzi, M.; Nettersheim, D.; Sullivan, M.; Frost, J.; Moore, G.; Vermeesch, J. R.; Fisk, N. M.; Thrasher, A. J.; Atala, A.; Adjaye, J.; Schorle, H.; De Coppi, P.; Guillot, P. V.: Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach. Molecular Therapy 20 (10), pp. 1953 - 1967 (2012)
  3. 3.
    Journal Article
    Drews, K.; Jozefczuk, J.; Prigione, A.; Adjaye, J.: Human induced pluripotent stem cells--from mechanisms to clinical applications. Journal of Molecular Medicine-JMM 90 (7), pp. 735 - 745 (2012)
  4. 4.
    Journal Article
    Drews, K.; Tavernier, G.; Demeester, J.; Lehrach, H.; de Smedt, S. C.; Rejman, J.; Adjaye, J.: The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts. Biomaterials 33 (16), pp. 4059 - 4068 (2012)
  5. 5.
    Journal Article
    Diedrichs, F.; Mlody, B.; Matz, P.; Fuchs, H.; Chavez, L.; Drews, K.; Adjaye, J.: Comparative molecular portraits of human unfertilized oocytes and primordial germ cells at 10 weeks of gestation. International Journal of Developmental Biology 56 (10-11-12), pp. 789 - 797 (2012)
  6. 6.
    Journal Article
    Tavernier, G.; Wolfrum, K.; Demeester, J.; De Smedt, S. C.; Adjaye, J.; Rejman, J.: Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc. Biomaterials 33 (2), pp. 412 - 7 (2012)
  7. 7.
    Journal Article
    Tavernier, G.; Wolfrum, K.; Demeester, J.; Smedt, D.; Adjaye, J.; Rejman, J.: Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc. Biomaterials 33 (2), pp. 412 - 417 (2012)
  8. 8.
    Journal Article
    Mah, N.; Wang, Y.; Liao, M. C.; Prigione, A.; Jozefczuk, J.; Lichtner, B.; Wolfrum, K.; Haltmeier, M.; Flottmann, M.; Schaefer, M. et al.; Hahn, A.; Mrowka, R.; Klipp, E.; Andrade-Navarro, M. A.; Adjaye, J.: Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network. PLoS ONE 6 (8), p. e24351 (2011)
  9. 9.
    Journal Article
    Wolfrum, K.; Wang, Y.; Prigione, A.; Sperling, K.; Lehrach, H.; Adjaye, J.: The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells. PLoS ONE 5 (10), p. e13703 - e13703 (2010)
  10. 10.
    Journal Article
    Wang, Y.; Mah, N.; Prigione, A.; Wolfrum, K.; Andrade-Navarro, M. A.; Adjaye, J.: A transcriptional roadmap to the induction of pluripotency in somatic cells. (2010)

Teaching (1)

  1. 11.
    Teaching
    Jozefczuk, J.; Drews, K.; Adjaye, J.: Preparation of mouse embryonic fibroblast cells suitable for culturing human embryonic and induced pluripotent stem cells.

Thesis - PhD (1)

  1. 12.
    Thesis - PhD
    Drews, K.: Viral and non-viral generation and characterization of induced pluripotent stem cells from human amniotic fluid cells. Dissertation, 198 pp. (2012)
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