Publikationen von Alexander Meissner

Basu, S.; Mackowiak, S.; Niskanen, H.; Knezevic, D.; Asimi, V.; Grosswendt, S.; Geertsema, H.; Ali, S.; Jerković, I.; Ewers, H. et al.; Mundlos, S.; Meissner, A.; Ibrahim, D. M.; Hnisz, D.: Unblending of Transcriptional Condensates in Human Repeat Expansion Disease. Cell 181 (5), S. 1062 - 1079 (2020)

Huyghe, A.; Furlan, G.; Ozmadenci, D.; Galonska, C.; Charlton, J.; Gaume, X.; Combémorel, N.; Riemenschneider, C.; Allègre, N.; Zhang, J. et al.; Wajda, P.; Rama, N.; Vieugué, P.; Durand, I.; Brevet , M.; Gadot, N.; Imhof, T.; Merrill , B. J.; Koch, M.; Mehlen, P.; Chazaud, C.; Meissner, A.; Lavial , F.: Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling. Nature Cell Biology 22 (4), S. 389 - 400 (2020)

Gokhman, D.; Nissim-Rafinia, M.; Agranat-Tamir, L.; Housman, G.; García-Pérez, R.; Lizano, E.; Cheronet, O.; Mallick, S.; Nieves-Colón, M. A.; Li, H. et al.; Alpaslan-Roodenberg, S.; Novak, M.; Gu, H.; Osinski, J. M.; Ferrando-Bernal, M.; Gelabert, P.; Lipende, I.; Mjungu, D.; Kondova, I.; Bontrop, R.; Kullmer, O.; Weber, G.; Shahar, T.; Dvir-Ginzberg, M.; Faerman, M.; Quillen, E. E.; Meissner, A.; Lahav, Y.; Kandel, L.; Liebergall, M.; Prada, M. E.; Vidal, J. M.; Gronostajski, R. M.; Stone, A. C.; Yakir, B.; Lalueza-Fox, C.; Pinhasi, R.; Reich, D.; Marques-Bonet, T.; Meshorer, E.; Carmel, L.: Differential DNA methylation of vocal and facial anatomy genes in modern humans. Nature Communications 11, 1189 (2020)

Alvarez-Dominguez, J. R.; Donaghey, J.; Rasouli, N.; Kenty, J. H. R.; Helman, A.; Charlton, J.; Straubhaar, J. R.; Meissner, A.; Melton, D. A.: Circadian Entrainment Triggers Maturation of Human In Vitro Islets. Cell Stem Cell 26 (1), S. 108 - 122 (2020)

Gießelmann, P.; Brändl, B.; Raimondeau, E.; Bowen, R.; Rohrandt, C.; Tandon, R.; Kretzmer, H.; Assum, G.; Galonska, C.; Siebert, R. et al.; Ammerpohl, O.; Heron, A.; Schneider, S. A.; Ladewig, J.; Koch, P.; Schuldt, B. M.; Graham, J. E.; Meissner, A.; Müller, F.-J.: Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing. Nature Biotechnology 37 (12), S. 1478 - 1481 (2019)

Kottakis, F.; Nicolay, B. N.; Roumane, A.; Karnik, R.; Gu, H.; Nagle, J. M.; Boukhali, M.; Hayward, M. C.; Li, Y. Y.; Chen, T. et al.; Liesa, M.; Hammerman, P. S.; Wong, K. K.; Hayes, D. N.; Shirihai, O. S.; Dyson, N. J.; Haas, W.; Meissner, A.; Bardeesy, N.: Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis. Nature 575 (7783), E5 (2019)

Andergassen, D.; Smith, Z. D.; Lewandowski, J. P.; Gerhardinger, C.; Meissner, A.; Rinn, J. L.: In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation. eLife 8, e47214 (2019)

Biran, A.; Kretzmer, H.; Yin, S.; Billington, L.; Regis, F. F.; Mohammad, A. W.; Gnirke, A.; Neuberg, D. S.; Carrasco, R. D.; Meissner, A. et al.; Wu, C. J.: Deciphering the Role of Locally Disordered DNA Methylation on CLL Development In Vivo. Blood 134 (Suppl. 1), S. 1737 - 1737 (2019)

Di Stefano, B.; Luo, E.-C.; Haggerty, C.; Aigner, S.; Charlton, J.; Brumbaugh, J.; Ji, F.; Rabano Jiménez, I.; Clowers, K. J.; Huebner, A. J. et al.; Clement, K.; Lipchina, I.; de Kort, M. A. C.; Anselmo, A.; Pulice, J.; Gerli, M. F. M.; Gu, H.; Gygi, S. P.; Sadreyev, R. I.; Meissner, A.; Yeo, G. W.; Hochedlinger, K.: The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell 25 (5), S. 622 - 638 (2019)

Brumbaugh , J.; Kim, I. S.; Ji, F.; Huebner, A. J.; Di Stefano , B.; Schwarz, B. A.; Charlton, J.; Coffey, A.; Choi, J.; Walsh, R. M. et al.; Schindler, J. W.; Anselmo, A.; Meissner, A.; Sadreyev, R. I.; Bernstein, B. E.; Hock, H.; Hochedlinger , K.: Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nature Cell Biology 21 (11), S. 1449 - 1461 (2019)

Thakurela, S.; Sindhu, C.; Yurkovsky, E.; Riemenschneider, C.; Smith, Z. D.; Nachman, I.; Meissner, A.: Differential regulation of OCT4 targets facilitates reacquisition of pluripotency. Nature Communications 10, 4444 (2019)

Tsankov, A. M.; Wadsworth, M. H.; Akopian, V.; Charlton, J.; Allon, S. J.; Arczewska, A. A.; Mead, B. E.; Drake, R. S.; Smith, Z. D.; Mikkelsen, T. S. et al.; Shalek, A. K.; Meissner, A.: Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development 146 (19), dev174722 (2019)

Jönsson, M. E.; Brattas, P. L.; Gustafsson, C.; Petri, R.; Yudovich, D.; Pircs, K.; Verschuere, S.; Madsen, S.; Hansson, J.; Larsson, J. et al.; Mansson, R.; Meissner, A.; Jakobsson, J.: Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nature Communications 10, 3182 (2019)

Giesselmann, P.; Hetzel, S.; Müller, F.-J.; Meissner, A.; Kretzmer, H.: Nanopype: A modular and scalable nanopore data processing pipeline. Bioinformatics 35 (22), S. 4770 - 4772 (2019)

Modic, M.; Grosch, M.; Rot, G.; Schirge, S.; Lepko, T.; Yamazaki, T.; Lee, F. C. Y.; Rusha, E.; Shaposhnikov, D.; Palo, M. et al.; Merl-Pham, J.; Cacchiarelli, D.; Rogelj, B.; Hauck, S. M.; von Mering, C.; Meissner, A.; Lickert, H.; Hirose, T.; Drukker, M.: Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition. Molecular Cell 74 (5), S. 951 - 965 (2019)

Chan, M. M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T. M.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Jones, M. G. et al.; Khodaverdian, A.; Nir, Y.; Meissner, A.; Weissman, J. S.: Molecular recording of mammalian Embryogenesis. Nature 570 (7759), S. 77 - 82 (2019)

Gaiti, F.; Chaligne, R.; Gu, H.; Brand, R. M.; Kothen-Hill, S.; Schulman, R. C.; Grigorev, K.; Risso, D.; Kim, K.-T.; Pastore, A. et al.; Huang, K. Y.; Alonso, A.; Sheridan, C.; Omans, N. D.; Biederstedt, E.; Clement, K.; Wang, L.; Felsenfeld, J. A.; Bhavsar, E. B.; Aryee, M. J.; Allan, J. N.; Furman, R.; Gnirke, A.; Wu, C. J.; Meissner, A.; Landau, D. A.: Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 569 (7757), S. 576 - 580 (2019)

Pastore, A.; Gaiti, F.; Lu, S. X.; Brand, R. M.; Kulm, S.; Chaligne, R.; Gu, H.; Huang, K. Y.; Stamenova, E. K.; Béguelin, W. et al.; Jiang, Y.; Chulman, R. C.; Kim, K.-T.; Alonso, A.; Allan, J. N.; Furman, R. R.; Gnirke, A.; Wu, C. J.; Melnick, A. M.; Meissner, A.; Bernstein, B. E.; Abdel-Wahab, O.; Landau, D. A.: Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nature Communications 10 (1), 1874 (2019)

Hinohara, K.; Wu, H.-J.; Vigneau, S.; McDonald, T. O.; Igarashi, K. J.; Yamamoto, K. N.; Madsen, T.; Fassl, A.; Egri, S. B.; Papanastasiou, M. et al.; Ding, L.; Peluffo, G.; Cohen, O.; Kales, S. C.; Lal-Nag, M.; Rai, G.; Maloney, D. J.; Jadhav, A.; Simeonov, A.; Wagle, N.; Brown, M.; Meissner, A.; Sicinski, P.; Jaffe, J. D.; Jeselsohn, R.; Gimelbrant, A. A.; Michor, F.; Polyak, K.: KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell 35 (2), S. 330 - 332 (2019)

Klein, H.-U.; McCabe, C.; Gjoneska, E.; Sullivan, S. E.; Kaskow, B. J.; Tang, A.; Smith, R. V.; Xu, J.; Pfenning, A. R.; Bernstein, B. E. et al.; Meissner, A.; Schneider, J. A.; Mostafavi, S.; Tsai, L.-H.; Young-Pearse, T. L.; Bennett, D. A.; De Jager, P. L.: Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience 22 (1), S. 37 - 46 (2019)