Publikationen von Marie-Laure Yaspo-Lehrach

Audrey Laurent, Manuela Calabrese, Hans Jörg Warnatz, Marie-Laure Yaspo-Lehrach, Vsevolod Tkachuk, Miguel Torres, Francesco Blasi, and Dimitry Penkov, "ChIP-Seq and RNA-Seq Analyses Identify Components of the Wnt and Fgf Signaling Pathways as Prep1 Target Genes in Mouse Embryonic Stem Cells," PLoS One (2015).

L. Gu, S. C. Frommel, C. C. Oakes, R. Simon, K. Grupp, C. Y. Gerig, D. Bar, M. D. Robinson, C. Baer, M. Weiss, Z. Gu, M. Schapira, R. Kuner, H. Sultmann, M. Provenzano, Icgc Project on Early Onset Prostate Cancer, M. L. Yaspo, B. Brors, J. Korbel, T. Schlomm, G. Sauter, R. Eils, C. Plass, and R. Santoro, "BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence," Nature Genetics 47 (1), 22-30 (2015).

S. Kärst, D. Arends, S. Heise, J. Trost, M. L. Yaspo, V. Amstislavskiy, T. Risch, H. Lehrach, and G. A. Brockmann, "Erratum to: 'The direction of cross affects obesity after puberty in male but not female offspring'," BMC Genomics 16 (1), 16:1018 (2015).

V. Pandey, M. Sultan, K. Kashofer, M. Ralser, V. Amstislavskiy, J. Starmann, I. Osprian, C. Grimm, H. Hache, M. L. Yaspo, H. Sultmann, M. Trauner, H. Denk, K. Zatloukal, H. Lehrach, and C. Wierling, "Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains," PLoS One 9 (10), e111006 (2014).

D. Henderson, L. A. Ogilvie, N. Hoyle, U. Keilholz, B. Lange, H. Lehrach, Consortium OncoTrack, and M. L. Yaspo, "Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack," Biotechnology Journal 9 (9), 1104-1114 (2014).

Marc Sultan, Vyacheslav Amstislavskiy, Thomas Risch, Moritz Schütte, Simon Dökel, Meryem Ralser, Daniela Balzereit, Hans Lehrach, and Marie Laure Yaspo, "Influence of RNA extraction methods and library selection schemes on RNA-seq data," BMC Genomics 15, 15:675 (2014).

Axel Rasche, Matthias Lienhard, Marie-Laure Yaspo, Hans Lehrach, and Ralf Herwig, "ARH-seq: identification of differential splicing in RNA-seq data," Nucleic Acids Research (London) 42 (14), e110 (2014).

P. A. Northcott, C. Lee, T. Zichner, A. M. Stütz, S. Erkek, D. Kawauchi, D. J. Shih, V. Hovestadt, M. Zapatka, D. Sturm, D. T. Jones, M. Kool, M. Remke, F. M. Cavalli, S. Zuyderduyn, G. D. Bader, S. VandenBerg, L. A. Esparza, M. Ryzhova, W. Wang, A. Wittmann, S. Stark, L. Sieber, H. Seker-Cin, L. Linke, F. Kratochwil, N. Jager, I. Buchhalter, C. D. Imbusch, G. Zipprich, B. Raeder, S. Schmidt, N. Diessl, S. Wolf, S. Wiemann, B. Brors, C. Lawerenz, J. Eils, H.-J. Warnatz, T. Risch, M. L. Yaspo, U. D. Weber, C. C. Bartholomae, C. von Kalle, E. Turanyi, P. Hauser, E. Sanden, A. Darabi, P. Siesjo, J. Sterba, K. Zitterbart, D. Sumerauer, P. van Sluis, R. Versteeg, R. Volckmann, J. Koster, M. U. Schuhmann, M. Ebinger, H. L. Grimes, G. W. Robinson, A. Gajjar, M. Mynarek, K. von Hoff, S. Rutkowski, T. Pietsch, W. Scheurlen, J. Felsberg, G. Reifenberger, A. E. Kulozik, A. von Deimling, O. Witt, R. Eils, R. J. Gilbertson, A. Korshunov, M. D. Taylor, P. Lichter, J. O. Korbel, R. J. Wechsler-Reya, and S. M. Pfister, "Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma," Nature 511 (7510), 428-434 (2014).

V. Colonna, Q. Ayub, Y. Chen, L. Pagani, P. Luisi, M. Pybus, E. Garrison, Y. Xue, C. Tyler-Smith, Consortium 1000 Genomes Project, R. Sudbrak, M. Albrecht, V. Amstislavskiy, T. A. Borodina, A. Dahl, A. Davydov, R. Herwig, P. Marquardt, F. Mertes, W. Nietfeld, D. Parkhomchuk, A. V. Soldatov, B. Timmermann, M. Tolzmann, H. Lehrach, and M. L. Yaspo, "Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences," Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014).

V. Hovestadt, D. T. Jones, S. Picelli, W. Wang, M. Kool, P. A. Northcott, M. Sultan, K. Stachurski, M. Ryzhova, H.-J. Warnatz, M. Ralser, S. Brun, J. Bunt, N. Jager, K. Kleinheinz, S. Erkek, U. D. Weber, C. C. Bartholomae, C. von Kalle, C. Lawerenz, J. Eils, J. Koster, R. Versteeg, T. Milde, O. Witt, S. Schmidt, S. Wolf, T. Pietsch, S. Rutkowski, W. Scheurlen, M. D. Taylor, B. Brors, J. Felsberg, G. Reifenberger, A. Borkhardt, H. Lehrach, R. J. Wechsler-Reya, R. Eils, M. L. Yaspo, P. Landgraf, A. Korshunov, M. Zapatka, B. Radlwimmer, S. M. Pfister, and P. Lichter, "Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing," Nature 510 (7506), 537-541 (2014).

O. Delaneau, J. Marchini, Consortium 1000 Genomes Project, H. Lehrach, R. Sudbrak, V. S. Amstislavskiy, M. Lienhard, F. Mertes, M. Sultan, B. Timmermann, M. L. Yaspo, and R. Herwig, "Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel," Nature Communications 5, 5:3934 (2014).

V Hovestadt , D Jones , S Picelli , W Wang , M Kool , P A Northcott , Marc Sultan, K Stachurski , M Ryzhova , Hans Joerg Warnatz, Markus Ralser, S Brun , J Bunt , N Jäger , K Kleinheinz , S Erkek , U D Weber , C C Bartholomae, C von Kalle , C Lawerenz , J Eils , J Koster , R Versteeg , T Milde , O Witt , S Schmidt , S Wolf , T Pietsch , S Rutkowski, W Scheurlen , M B Taylor , B Brors , J Felsberg , G Reifenberger , A Borkhardt , H. Lehrach, R Wechsler-Reya , R Eils , Marie-Laure Yaspo, P Landgraf , A Korshunov , M Zapatka , B Radlwimmer , S M Pfister , and P Lichter , "Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing," Nature 26 (510), 537-541 (2014).

S. Rashi-Elkeles, H. J. Warnatz, R. Elkon, A. Kupershtein, Y. Chobod, A. Paz, V. Amstislavskiy, M. Sultan, H. Safer, W. Nietfeld, H. Lehrach, R. Shamir, M. L. Yaspo, and Y. Shiloh, "Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation," Science Signaling 7 (325), rs3 (2014).

E. Khurana, Y. Fu, V. Colonna, X. J. Mu, H. M. Kang, T. Lappalainen, A. Sboner, L. Lochovsky, J. Chen, A. Harmanci, J. Das, A. Abyzov, S. Balasubramanian, K. Beal, D. Chakravarty, D. Challis, Y. Chen, D. Clarke, L. Clarke, F. Cunningham, U. S. Evani, P. Flicek, R. Fragoza, E. Garrison, R. Gibbs, Z. H. Gumus, J. Herrero, N. Kitabayashi, Y. Kong, K. Lage, V. Liluashvili, S. M. Lipkin, D. G. MacArthur, G. Marth, D. Muzny, T. H. Pers, G. R. Ritchie, J. A. Rosenfeld, C. Sisu, X. Wei, M. Wilson, Y. Xue, F. Yu, Consortium 1000 Genomes Project, H. Lehrach, R. Sudbrak, M. W. Albrecht, V. Amstislavskiy, T. A. Borodina, M. Lienhard, F. Mertes, M. Sultan, B. Timmermann, M. L. Yaspo, E. T. Dermitzakis, H. Yu, M. A. Rubin, C. Tyler-Smith, and M. Gerstein, "Integrative annotation of variants from 1092 humans: application to cancer genomics," Science 342 (6154), 1235587-1235587 (2013).

N. Jager, M. Schlesner, D. T. Jones, S. Raffel, J. P. Mallm, K. M. Junge, D. Weichenhan, T. Bauer, N. Ishaque, M. Kool, P. A. Northcott, A. Korshunov, R. M. Drews, J. Koster, R. Versteeg, J. Richter, M. Hummel, S. C. Mack, M. D. Taylor, H. Witt, B. Swartman, D. Schulte-Bockholt, M. Sultan, M. L. Yaspo, H. Lehrach, B. Hutter, B. Brors, S. Wolf, C. Plass, R. Siebert, A. Trumpp, K. Rippe, I. Lehmann, P. Lichter, S. M. Pfister, and R. Eils, "Hypermutation of the inactive X chromosome is a frequent event in cancer," Cell 155 (3), 567-81 (2013).

D. T. Jones, B. Hutter, N. Jager, A. Korshunov, M. Kool, H. J. Warnatz, T. Zichner, S. R. Lambert, M. Ryzhova, D. A. Quang, A. M. Fontebasso, A. M. Stutz, S. Hutter, M. Zuckermann, D. Sturm, J. Gronych, B. Lasitschka, S. Schmidt, H. Seker-Cin, H. Witt, M. Sultan, M. Ralser, P. A. Northcott, V. Hovestadt, S. Bender, E. Pfaff, S. Stark, D. Faury, J. Schwartzentruber, J. Majewski, U. D. Weber, M. Zapatka, B. Raeder, M. Schlesner, C. L. Worth, C. C. Bartholomae, C. von Kalle, C. D. Imbusch, S. Radomski, C. Lawerenz, P. van Sluis, J. Koster, R. Volckmann, R. Versteeg, H. Lehrach, C. Monoranu, B. Winkler, A. Unterberg, C. Herold-Mende, T. Milde, A. E. Kulozik, M. Ebinger, M. U. Schuhmann, Y. J. Cho, S. L. Pomeroy, A. von Deimling, O. Witt, M. D. Taylor, S. Wolf, M. A. Karajannis, C. G. Eberhart, W. Scheurlen, M. Hasselblatt, K. L. Ligon, M. W. Kieran, J. O. Korbel, M. L. Yaspo, B. Brors, J. Felsberg, G. Reifenberger, V. P. Collins, N. Jabado, R. Eils, P. Lichter, and S. M. Pfister, "Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma," Nature Genetics 45 (8), 927-32 (2013).

D. Penkov, D. Mateos San Martin, L. C. Fernandez-Diaz, C. A. Rossello, C. Torroja, F. Sanchez-Cabo, H.J. Warnatz, M. Sultan, M. L. Yaspo Lehrach, A. Gabrieli, V. Tkachuk, A. Brendolan, F. Blasi, and M. Torres, "Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins," Cell Reports 3 (4), 1321-33 (2013).

J. Weischenfeldt, R. Simon, L. Feuerbach, K. Schlangen, D. Weichenhan, S. Minner, D. Wuttig, H. J. Warnatz, H. Stehr, T. Rausch, N. Jager, L. Gu, O. Bogatyrova, A. M. Stutz, R. Claus, J. Eils, R. Eils, C. Gerhauser, P. H. Huang, B. Hutter, R. Kabbe, C. Lawerenz, S. Radomski, C. C. Bartholomae, M. Falth, S. Gade, M. Schmidt, N. Amschler, T. Hass, R. Galal, J. Gjoni, R. Kuner, C. Baer, S. Masser, C. von Kalle, T. Zichner, V. Benes, B. Raeder, M. Mader, V. Amstislavskiy, M. Avci, H. Lehrach, D. Parkhomchuk, M. Sultan, L. Burkhardt, M. Graefen, H. Huland, M. Kluth, A. Krohn, H. Sirma, L. Stumm, S. Steurer, K. Grupp, H. Sultmann, G. Sauter, C. Plass, B. Brors, Marie L. Yaspo Lehrach, J. O. Korbel, and T. Schlomm, "Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer," Cancer Cell 23 (2), 159-70 (2013).

Goncalo R. Abecasis, Adam Auton, Lisa D. Brooks, Mark A. DePristo, Richard M. Durbin, Robert E. Handsaker, Hyun Min Kang, Gabor T. Marth, Gil A. McVean, The 1000 Genomes Project Consortium, Ralf Sudbrak, Marcus Albrecht, Vyacheslav Amstislavskiy, Tatiana A. Borodina, Alexey Davydov, Ralf Herwig, Matthias Lienhard, Florian Mertes, Marc Sultan, Bernd Timmermann, Marie L. Yaspo, and Hans Lehrach, "An integrated map of genetic variation from 1,092 human genomes," Nature 491 (7422), 56-65 (2012).

M. Sultan, S. Dokel, V. Amstislavskiy, D. Wuttig, H. Sultmann, H. Lehrach, and M. L. Yaspo, "A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods," Biochemical and Biophysical Research Communications 422 (4), 643-646 (2012).