Publikationen von M. L. Yaspo

L. Grassi, F. Pourfarzad, S. Ullrich, A. Merkel, F. Were, E. Carrillo-de-Santa-Pau, G. Yi, I. H. Hiemstra, A. T. J. Tool, E. Mul, J. Perner, E. Janssen-Megens, K. Berentsen, H. Kerstens, E. Habibi, M. Gut, M. L. Yaspo, M. Linser, E. Lowy, A. Datta, L. Clarke, P. Flicek, M. Vingron, D. Roos, T. K. van den Berg, S. Heath, D. Rico, M. Frontini, M. Kostadima, I. Gut, A. Valencia, W. H. Ouwehand, H. G. Stunnenberg, J. H. A. Martens, and T. W. Kuijpers, "Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils," Cell Reports 24 (10), 2784-2794 (2018).

Praneeth Reddy Devullapally, Jörg Bürger, Thorsten Mielke, Zoltán Konthur, Hans Lehrach, Marie-Laure Yaspo, Jörn Glökler, and Hans-Jörg Warnatz, "Simple paired heavy- and light-chain antibody repertoire sequencing using endoplasmic reticulum microsomes," Genome Medicine 10, 10:34 (2018).

A. E. Marneth, K. H. M. Prange, A. S. A. Al Hinai, S. M. Bergevoet, N. Tesi, E. M. Janssen-Megens, B. Kim, N. Sharifi, M. L. Yaspo, J. Kuster, M. A. Sanders, E. C. G. Stoetman, J. Knijnenburg, Tcjm Arentsen-Peters, C. M. Zwaan, H. G. Stunnenberg, M. M. van den Heuvel-Eibrink, T. Haferlach, M. Fornerod, J. H. Jansen, P. J. M. Valk, B. A. van der Reijden, and J. H. A. Martens, "C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation," Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 2017, 1-9 (2017).

P. A. Northcott, I. Buchhalter, A. S. Morrissy, V. Hovestadt, J. Weischenfeldt, T. Ehrenberger, S. Gröbner, M. Segura-Wang, T. Zichner, V. A. Rudneva, H. J. Warnatz, N. Sidiropoulos, A. H. Phillips, S. Schumacher, K. Kleinheinz, S. M. Waszak, S. Erkek, D. T. W. Jones, B. C. Worst, M. Kool, M. Zapatka, N. Jager, L. Chavez, B. Hutter, M. Bieg, N. Paramasivam, M. Heinold, Z. Gu, N. Ishaque, C. Jager-Schmidt, C. D. Imbusch, A. Jugold, D. Hubschmann, T. Risch, V. Amstislavskiy, F. G. R. Gonzalez, U. D. Weber, S. Wolf, G. W. Robinson, X. Zhou, G. Wu, D. Finkelstein, Y. Liu, F. M. G. Cavalli, B. Luu, V. Ramaswamy, X. Wu, J. Koster, M. Ryzhova, Y. J. Cho, S. L. Pomeroy, C. Herold-Mende, M. Schuhmann, M. Ebinger, L. M. Liau, J. Mora, R. E. McLendon, N. Jabado, T. Kumabe, E. Chuah, Y. Ma, R. A. Moore, A. J. Mungall, K. L. Mungall, N. Thiessen, K. Tse, T. Wong, S. J. M. Jones, O. Witt, T. Milde, A. Von Deimling, D. Capper, A. Korshunov, M. L. Yaspo, R. Kriwacki, A. Gajjar, J. Zhang, R. Beroukhim, E. Fraenkel, J. O. Korbel, B. Brors, M. Schlesner, R. Eils, M. A. Marra, S. M. Pfister, M. D. Taylor, and P. Lichter, "The whole-genome landscape of medulloblastoma subtypes," Nature 547 (7663), 311-317 (2017).

M. Schütte, L. A. Ogilvie, D. T. Rieke, B. M. H. Lange, M. L. Yaspo, and H. Lehrach, "Cancer Precision Medicine: Why More Is More and DNA Is Not Enough," Public Health Genomics 20 (2), 70-80 (2017).

M. Schütte, T. Risch, N. Abdavi Azar, K. Boehnke, D. Schumacher, M. Keil, R. Yildiriman, C. Jandrasits, T. Borodina, V. Amstislavskiy, C. L. Worth, C. Schweiger, S. Liebs, M. Lange, H. J. Warnatz, L. M. Butcher, J. E. Barrett, M. Sultan, C. Wierling, N. Golob-Schwarzl, S. Lax, S. Uranitsch, M. Becker, Y. Welte, J. L. Regan, M. Silvestrov, I. Kehler, A. Fusi, T. Kessler, R. Herwig, U. Landegren, D. Wienke, M. Nilsson, J. A. Velasco, P. Garin-Chesa, C. Reinhard, S. Beck, R. Schafer, C. R. Regenbrecht, D. Henderson, B. Lange, J. Haybaeck, U. Keilholz, J. Hoffmann, H. Lehrach, and M. L. Yaspo, "Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors," Nature Communications 8, 8:14262 (2017).

H. Li, L. Frappart, J. Moll, A. Winkler, T. Kroll, J. Hamann, I. Kufferath, M. Groth, S. Taudien, M. Schütte, M. L. Yaspo, H. Heuer, B. M. Lange, M. Platzer, K. Zatloukal, P. Herrlich, and A. Ploubidou, "Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma," Cancer research: an official organ of the American Association for Cancer Research 76 (21), 6382-6395 (2016).

G. D. Poznik, Y. Xue, F. L. Mendez, T. F. Willems, A. Massaia, M. A. Wilson Sayres, Consortium The 1000 Genomes Projekt, H. Lehrach, R. Sudbrak, M. W. Albrecht, V. Amstislavskiy, T. A. Borodina, M. Lienhard, F. Mertes, M. Sultan, B. Timmermann, and M.-L. Yaspo, "Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences," Nature Genetics 48 (6), 593-599 (2016).

S. Oh, R. A. Flynn, S. N. Floor, J. Purzner, L. Martin, B. T. Do, S. Schubert, D. Vaka, S. Morrissy, Y. Li, M. Kool, V. Hovestadt, D. T. Jones, P. A. Northcott, T. Risch, H. J. Warnatz, M. L. Yaspo, C. M. Adams, R. D. Leib, M. Breese, M. A. Marra, D. Malkin, P. Lichter, J. A. Doudna, S. M. Pfister, M. D. Taylor, H. Y. Chang, and Y. J. Cho, "Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress," Oncotarget 7 (19), 28169-28182 (2016).

C. Y. Lin, S. Erkek, Y. Tong, L. Yin, A. J. Federation, M. Zapatka, P. Haldipur, D. Kawauchi, T. Risch, H. J. Warnatz, B. C. Worst, B. Ju, B. A. Orr, R. Zeid, D. R. Polaski, M. Segura-Wang, S. M. Waszak, D. T. Jones, M. Kool, V. Hovestadt, I. Buchhalter, L. Sieber, P. Johann, L. Chavez, S. Groschel, M. Ryzhova, A. Korshunov, W. Chen, V. V. Chizhikov, K. J. Millen, V. Amstislavskiy, H. Lehrach, M. L. Yaspo, R. Eils, P. Lichter, J. O. Korbel, S. M. Pfister, J. E. Bradner, and P. A. Northcott, "Active medulloblastoma enhancers reveal subgroup-specific cellular origins," Nature 530 (7588), 57-62 (2016).

L. Chen, B. Ge, F. P. Casale, L. Vasquez, T. Kwan, D. Garrido-Martin, S. Watt, Y. Yan, K. Kundu, S. Ecker, A. Datta, D. Richardson, F. Burden, D. Mead, A. L. Mann, J. M. Fernandez, S. Rowlston, S. P. Wilder, S. Farrow, X. Shao, J. J. Lambourne, A. Redensek, C. A. Albers, V. Amstislavskiy, S. Ashford, K. Berentsen, L. Bomba, G. Bourque, D. Bujold, S. Busche, M. Caron, S. H. Chen, W. Cheung, O. Delaneau, E. T. Dermitzakis, H. Elding, I. Colgiu, F. O. Bagger, P. Flicek, E. Habibi, V. Iotchkova, E. Janssen-Megens, B. Kim, H. Lehrach, E. Lowy, A. Mandoli, F. Matarese, M. T. Maurano, J. A. Morris, V. Pancaldi, F. Pourfarzad, K. Rehnstrom, A. Rendon, T. Risch, N. Sharifi, M. M. Simon, M. Sultan, A. Valencia, K. Walter, S. Y. Wang, M. Frontini, S. E. Antonarakis, L. Clarke, M. L. Yaspo, S. Beck, R. Guigo, D. Rico, J. H. A. Martens, W. H. Ouwehand, T. W. Kuijpers, D. S. Paul, H. G. Stunnenberg, O. Stegle, K. Downes, T. Pastinen, and N. Soranzo, "Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells," Cell 167 (5), 1398-1414 (2016).

A. Perdomo-Sabogal, K. Nowick, I. Piccini, R. Sudbrak, H. Lehrach, M. L. Yaspo, H. J. Warnatz, and R. Querfurth, "Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa)," Molecular Biology and Evolution 33 (5), 1231-1244 (2016).

Stefan Kärst, Danny Arends, Sebastian Heise, Jan Trost, Marie-Laure Yaspo-Lehrach, Vyacheslav Amstislavskiy, Thomas Risch, Hans Lehrach, and Gudrun Brockmann, "Erratum," BMC Genomics 16, 1018-1018 (2015).

Stefan Kärst, Danny Arends, Sebastian Heise, Jan Trost, Marie-Laure Yaspo-Lehrach, Vyacheslav Amstislavskiy, Thomas Risch, and Hans Lehrach, "The direction of cross affects [corrected] obesity after puberty in male but not female offspring," BMC Genomics 16, 904 (2015).

The 1000 Genome Project Consortium, Hans Lehrach, Vyacheslav Amstislavskiy, Matthias Lienhard, Florian Mertes, Marc Sultan, Bernd Timmermann, Marie-Laure Yaspo, and Ralf Herwig, "A global reference for human genetic variation," Nature 526 (7571), 68-74 (2015).

U. Fischer, M. Forster, A. Rinaldi, T. Risch, S. Sungalee, H. J. Warnatz, B. Bornhauser, M. Gombert, C. Kratsch, A. M. Stutz, M. Sultan, J. Tchinda, C. L. Worth, V. Amstislavskiy, N. Badarinarayan, A. Baruchel, T. Bartram, G. Basso, C. Canpolat, G. Cario, H. Cave, D. Dakaj, M. Delorenzi, M. P. Dobay, C. Eckert, E. Ellinghaus, S. Eugster, V. Frismantas, S. Ginzel, O. A. Haas, O. Heidenreich, G. Hemmrich-Stanisak, K. Hezaveh, J. I. Holl, S. Hornhardt, P. Husemann, P. Kachroo, C. P. Kratz, G. T. Kronnie, B. Marovca, F. Niggli, A. C. McHardy, A. V. Moorman, R. Panzer-Grumayer, B. S. Petersen, B. Raeder, M. Ralser, P. Rosenstiel, D. Schäfer, M. Schrappe, S. Schreiber, M. Schutte, B. Stade, R. Thiele, Nv Weid, A. Vora, M. Zaliova, L. Zhang, T. Zichner, M. Zimmermann, H. Lehrach, A. Borkhardt, J. P. Bourquin, A. Franke, J. O. Korbel, M. Stanulla, and M. L. Yaspo, "Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options," Nature Genetics 47 (9), 1020-1029 (2015).

Christoph K. Wierling, Thomas Kessler, Lesley A. Ogilvie, Bodo Lange, Marie-Laure Yaspo, and Hans Lehrach, "Network and systems biology: essential steps in virtualising drug discovery and development.," Drug Discovery Today: Technology 15, 33-40 (2015).

K. W. Pajtler, H. Witt, M. Sill, D. T. Jones, V. Hovestadt, F. Kratochwil, K. Wani, R. Tatevossian, C. Punchihewa, P. Johann, J. Reimand, H.-J. Warnatz, M. Ryzhova, S. Mack, V. Ramaswamy, D. Capper, L. Schweizer, L. Sieber, A. Wittmann, Z. Huang, P. van Sluis, R. Volckmann, J. Koster, R. Versteeg, D. Fults, H. Toledano, S. Avigad, L. M. Hoffman, A. M. Donson, N. Foreman, E. Hewer, K. Zitterbart, M. Gilbert, T. S. Armstrong, N. Gupta, J. C. Allen, M. A. Karajannis, D. Zagzag, M. Hasselblatt, A. E. Kulozik, O. Witt, V. P. Collins, K. von Hoff, S. Rutkowski, T. Pietsch, G. Bader, M. L. Yaspo, A. von Deimling, P. Lichter, M. D. Taylor, R. Gilbertson, D. W. Ellison, K. Aldape, A. Korshunov, M. Kool, and S. M. Pfister, "Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups," Cancer Cell 27 (5), 728-743 (2015).

T. Redmer, Y. Welte, D. Behrens, I. Fichtner, D. Przybilla, W. Wruck, M. L. Yaspo, H. Lehrach, R. Schäfer, and C. R. Regenbrecht, "The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells," PLoS One 9 (5), e92596 (2015).

A. Laurent, M. Calabrese, H. J. Warnatz, M. L. Yaspo, V. Tkachuk, M. Torres, F. Blasi, and D. Penkov, "ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells," PLoS One 10 (4), e0122518 (2015).