Publikationen von Marie-Laure Yaspo

Juan Lazaro-Navarro, Clara Alcon, Mathurin Dorel, Lina Alasfar, Lorenz Bastian, Claudia Baldus, Kathy Astrahantseff, Marie-Laure Yaspo, Joan Montero, and Cornelia Eckert, "Inhibiting H3K27 Demethylases Downregulates CREB-CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia," Cancer Medicine 14 (1), 1-7 (2025).

André Bortolini Silveira, Alexandre Houy, Olivier Ganier, Begüm Özemek, Sandra Vanhuele, Anne Vincent-Salomon, Nathalie Cassoux, Pascale Mariani , Gaelle Pierron, Serge Leyvraz, Damian Rieke, Alberto Picca, Franck Bielle, Marie-Laure Yaspo, Manuel Rodrigues, and Marc-Henri Stern, "Base-excision repair pathway shapes 5-methylcytosine deamination signatures in pan-cancer genomes," Nature Communications 15 (1), Article 9864 (2024).

Steffen E. Künzel, Dominik P. Frentzel, Leonie T. M. Flesch, Vitus A. Knecht, Anne Rübsam, Felix Dreher, Moritz Schütte, Alexandre Dubrac, Bodo Lange, Marie-Laure Yaspo, Hans Lehrach, Antonia M. Joussen, and Oliver Zeitz, "AI-driven discovery of blood xenobiotic biomarkers in neovascular age-related macular degeneration using iterative random forests," Graefe's Archive for Clinical and Experimental Ophthalmology 262 (11), 3567-3575 (2024).

Steffen E. Künzel, Inga-Marie Pompös, Leonie T. M. Flesch, Dominik P. Frentzel, Vitus A. Knecht, Silvia Winkler, Sergej Skosyrski, Anne Rübsam, Felix Dreher, Norbert Kociok, Moritz Schütte, Alexandre Dubrac, Bodo Lange, Marie-Laure Yaspo, Hans Lehrach, Olaf Strauß, Antonia M. Joussen, and Oliver Zeitz, "Exploring the Impact of Saccharin on Neovascular Age-Related Macular Degeneration: A Comprehensive Study in Patients and Mice," Investigative Ophthalmology and Visual Science 65 (4), Article 5 (2024).

Michelle Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Marit Willemijn Vermunt, Robert Winkler, Leah Schüler, Oriol Alejo, Konstantin Schuschel, Eniko Regenyi, Dorit Borchert, Michael Heuser, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, and Jan-Henning Klusmann, "Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15," iScience 26 (10), 107844 (2023).

Sofia Gialesaki , Daniela Bräuer-Hartmann , Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Eniko Regenyi, Konstantin Schuschel, Maurice Labuhn , Michelle Ng, Robert Winkler , Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, and Jan-Henning Klusmann, "RUNX1 isoform disequilibrium promotes the development of trisomy 21 associated myeloid leukemia," Blood 141 (10), 1105-1118 (2022).

Serge Leyvraz, Frank Konietschke, Caroline Peuker, Moritz Schütte, Thomas Kessler, Sebastian Ochsenreither, Marc Ditzhaus, Erin D. Sprünken, Gina Dörpholz, Mario Lamping, Damian T. Rieke, Konrad Klinghammer, Susen Burock, Claas Ulrich, Gabriela Poch, Reinhold Schäfer, Frederick Klauschen, Antonia Joussen, Marie-Laure Yaspo, and Ulrich Keilholz, "Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study," European Journal of Cancer 169, 146-155 (2022).

Vincent Vuaroqueaux, Alexandra Musch, Dennis Kobelt, Thomas Risch, Pia Herrmann, Susen Burock, Anne-Lise Peille, Marie-Laure Yaspo, Heinz-Herbert Fiebig, and Ulrike Stein, "Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival," Cancers / Molecular Diversity Preservation International (MDPI) 14 (7), 1749 (2022).

Oriol Alejo-Valle, Karoline Weigert, Raj Bhayadia, Michelle Ng, Hasan Issa, Christoph Beyer, Stephan Emmrich, Konstantin Schuschel, Christian Ihling, Andrea Sinz, Martin Zimmermann, Claudia Wickenhauser, Marius Flasinski, Eniko Regenyi, Maurice Labuhn, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, and Jan-Henning Klusmann, "The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis," Blood 139 (5), 651-665 (2022).

Marlen Keil, Theresia Conrad, Michael Becker, Ulrich Keilholz, Marie-Laure Yaspo, Hans Lehrach, Moritz Schütte, Johannes Haybaeck, and Jens Hoffmann, "Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data," Cancers 13 (23), 6018 (2021).

Yi Xiao, Anja Rabien, Rene Buschow, Vyacheslav Amstislavskiy, Jonas Busch, Ergin Kilic, Sonia L. Villegas, Bernd Timmermann, Moritz Schütte, Thorsten Mielke, Marie-Laure Yaspo, Klaus Jung, and David Meierhofer, "Endocytosis-mediated replenishment of amino acids favors cancer cell proliferation and survival in chromophobe renal cell carcinoma," Cancer research: an official organ of the American Association for Cancer Research 80, 5491-5501 (2020).

Beat Bornhauser, Gunnar Cario, Anna Rinaldi, Thomas Risch, Virginia Rodriguez Martinez, Moritz Schütte, Hans-Jörg Warnatz, Nastassja Scheidegger, Paulina Mirkowska, Martina Temperli, Claudia Möller, Angela Schumich, Michael Dworzak, Andishe Attarbaschi, Monika Brüggemann, Mathias Ritgen, Ester Mejstrikova, Andreas Hofmann, Barbara Buldini, Pamela Scarparo, Guiseppe Basso, Oscar Maglia, Guiseppe Gaipa, Tessa-Lara Skoblyn, Geertruij Te Kronnie, Elena Vendramini, Renate Panzer-Grümayer, Malwine Jeanette Barz, Blerim Marovca, Mathias Hauri-Hohl, Felix Niggli, Cornelia Eckert, Martin Schrappe, Martin Stanulla, Martin Zimmermann, Bernd Wollscheid, Marie-Laure Yaspo, and Jean-Pierre Bourquin, "The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL," Blood Advances 4 (17), 4052-4064 (2020).

Marie Burns, Axel R. Schulz, Désirée Kunkel, Manfred Hönig, Sarah Warth, Bertram Bengsch, Tyler Burns, Julia Reinhardt, Andreas Grützkau, Marie-Laure Yaspo, Jan Sodenkamp, Ute Hoffmann, and Henrik E. Mei, "Mass Cytometry-A Tool for the Curious: Networking in Berlin," Cytometry Part A 97 (8), 764-767 (2020).

Rita Lampignano , Martin H.D. Neumann, Sabrina Weber, Vera Kloten, Andrei Herdean, Thorsten Voss, Daniel Groelz, Anna Babayan, Marco Tibbesma, Martin Schlumpberger, Francesca Chemi, Dominic G. Rothwell, Harriet Wikman, Jean-Pierre Galizzi, Inger Riise Bergheim, Hege Russnes, Benedetta Mussolin, Serena Bonin, Christine Voigt, Hanny Musa, Pamela Pinzani, Evi Lianidou, Ged Brady, Michael R. Speicher, Klaus Pantel, Fay Betsou, Ed Schuuring, Mikael Kubista, Wim Ammerlaan, Markus Sprenger-Haussels, Thomas Schlange, Ellen Heitzer, Hans Lehrach, and Marie-Laure Yaspo, "Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows," Clinical Chemistry: International Journal of Molecular Diagnostics and Laboratory Medicine 66 (1), 149-160 (2020).

Yun Huang, Brice Mouttet , Hans-Jörg Warnatz, Thomas Risch, Fabian Rietmann, Fabian Frommelt, Quy A. Ngo, Maria Pamela Dobay, Blerim Marovca, Silvia Jenni, Yi-Chien Tsai, Sören Matzk, Vyacheslav Amstislavskiy, Martin Schrappe, Martin Stanulla, Matthias Gstaiger, Beat Bornhauser, Marie-Laure Yaspo, and Jean-Pierre Bourquin , "The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability," Cancer Cell 36 (6), 630-644 (2019).

Sophia Schade, Lesley A. Ogilvie, Thomas Kessler, Moritz Schütte, Christoph Wierling, Bodo M. Lange, Hans Lehrach, and Marie-Laure Yaspo, "A data- and model-driven approach for cancer treatment," Der Onkologe 25 (Suppl. 2), S132-S137 (2019).

Maurice Labuhn, Kelly Perkins, Sören Matzk, Leila Varghese, Catherine Garnett, Elli Papaemmanuil, Marlen Metzner, Alison Kennedy, Vyacheslav Amstislavskiy, Thomas Risch, Raj Bhayadia, David Samulowski, David Cruz Hernandez, Bilyana ... Stoilova, Marie-Laure Yaspo, Peter J. Campbell, Irene Roberts, Stefan N. Constantinescu, Paresh Vyas, Dirk Heckl, and Jan-Henning Klusmann, "Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome," Cancer Cell 36 (2), 123-138 (2019).

Sophia Schade, Lesley A. Ogilvie, Thomas Kessler, Moritz Schütte, Christoph Wierling, Bodo M. Lange, Hans Lehrach, and Marie-Laure Yaspo, "Ein daten- und modellgesteuerter Ansatz zur Behandlung maligner Tumoren," Der Onkologe 25 (Suppl. 1), S109-S115 (2019).

Guoqiang Yi, Albertus T. J. Wierenga, Francesca Petraglia, Pankaj Narang, Eva M. Janssen-Megens, Amit Mandoli, Angelika Merkel, Kim Berentsen, Bowon Kim, Filomena Matarese, Abhishek A. Singh, Ehsan Habibi, Koen H. M. Prange, Andre B. Mulder, Joop H. Jansen, Laura Clarke, Simon Heath, Bert A. van der Reijden, Paul Flicek, Marie-Laure Yaspo, Ivo Gut, Christoph Bock, Jan Jacob Schuringa, Lucia Altucci, Edo Vellenga, Hendrik G. Stunnenberg, and Joost H. A. Martens, "Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes," Cell Reports 26 (4), 1059-1069 (2019).

Clarissa Gerhauser, Francesco Favero, Thomas Risch, Ronald Simon, Lars Feuerbach, Yassen Assenov, Doreen Heckmann, Nikos Sidiropoulos, Sebastian M. Waszak, Daniel Hübschmann, Alfonso Urbanucci, Etsehiwot G. Girma, Vladimir Kuryshev, Leszek J. Klimczak, Natalie Saini, Adrian M. Stütz, Dieter Weichenhan, Lisa-Marie Böttcher, Reka Toth, Josephine D. Hendriksen, Christina Koop, Pavlo Lutsik, Sören Matzk, Hans-Jörg Warnatz, Vyacheslav Amstislavskiy, Clarissa Feuerstein, Benjamin Raeder, Olga Bogatyrova, Eva-Maria Schmitz, Claudia Hube-Magg, Martina Kluth, Hartwig Huland, Markus Graefen, Chris Lawerenz, Gervaise H. Henry, Takafumi N. Yamaguchi, Alicia Malewska, Jan Meiners, Daniela Schilling, Eva Reisinger, Roland Eils, Matthias Schlesner, Douglas W. Strand, Robert G. Bristow, Paul C. Boutros, Christof von Kalle, Dmitry Gordenin, Holger Sültmann, Benedikt Brors, Guido Sauter, Christoph Plass, Marie-Laure Yaspo, Jan O. Korbel, Thorsten Schlomm, and Joachim Weischenfeldt, "Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories," Cancer Cell 34 (6), 996-1011 (2018).