Publikationen von F. Witte

F. Witte, D. Chan, A. N. Economides, S. Mundlos, and S. Stricker, "Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region," Proceedings of the National Academy of Sciences U S A 107 (32), 14211-14216 (2010).

F. Witte, O. Bernatik, K. Kirchner, J. Masek, A. Mahl, P. Krejci, S. Mundlos, A. Schambony, V. Bryja, and S. Stricker, "Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.," The FASEB Journal 24 (7), 2417-2426 (2010).

Nicole Verhey van Wijk, Florian Witte, Ann Carolin Feike, Alexandra Schambony, Walter Birchmeier, Stefan Mundlos, and Sigmar Stricker, "The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling," Biochemical and Biophysical Research Communications 390 (2), 211-216 (2009).

Wibke Schwarzer, Florian Witte, Anna Rajab, Stefan Mundlos, and Sigmar Stricker, "A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes," Human Molecular Genetics 18 (21), 4013-4021 (2009).

Bo Gao, Jianxin Hu, Sigmar Stricker, Martin Cheung, Gang Ma, Kit Fong Law, Florian Witte, James Briscoe, Stefan Mundlos, Lin He, Kathryn S. E. Cheah, and Danny Chan, "A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range," Nature 458 (7242), 1196-1200 (2009).

Florian Witte, Janine Dokas, Franziska Neuendorf, Stefan Mundlos, and Sigmar Stricker, "Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation," Gene Expression Patterns 9 (4), 215-223 (2009).

Pia Kuss, Pablo Villavicencio-Lorini, Florian Witte, Joachim Klose, Andrea N. Albrecht, Petra Seemann, Jochen Hecht, and Stefan Mundlos, "Mutant Hoxd13 induces extra digits in a mouse model of synpolydactyly directly and by decreasing retinoic acid synthesis," Journal of Clinical Investigation 119 (1), 146-156 (2009).

Regina Raz, Sigmar Stricker, Elizabetta Elizabetta Gazzerro, Julie L. Clor, Florian Witte, Harakiran Nistala, Stefanie Zabski, Renata C. Pereira, Lisa Stadmeyer, Xiangmin Wang, Lori Gowen, Mark W. Sleeman, George D. Yancopoulos, Ernesto Canalis, Stefan Mundlos, David M. V Valenzuela, and Aris N. Economides, "The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome," Development 135 (9), 1713-1723 (2008).

Sigmar Stricker, Nicole Verhey Van Wijk, Florian Witte, Norbert Brieske, Kathrin Seidel, and Stefan Mundlos, "Cloning and expression pattern of chicken Ror2 and functional characterization of truncating mutations in Brachydactyly type B and Robinow syndrome," Developmental Dynamics 235 (12), 3456-3465 (2006).

Florian Witte, Analyse der Ror2-Funktion in vivo und in vitro: die Ror2W749X-Maus als Modell für humane Brachydaktylie Typ B, PhD Thesis, Freie Universität, 2009.