Publikationen von B. Timmermann

C. Röhr, M. Kerick, A. Fischer, A. Kuehn, K. Kashofer, B. Timmermann, A. Daskalaki, T. Meinel, D. Drichel, S. Börno, A. Nowka, S. Krobitsch, A. C. McHardy, C. Kratsch, T. Becker, A. Wunderlich, C. Barmeyer, C. Viertler, K. Zatloukal, C. Wierling, H. Lehrach, and M.-R. Schweiger, "High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications," PLoS One 8 (7), e67461-e67461 (2013).

S. B. Montgomery, D. L. Goode, E. Kvikstad, C. H. Albers, Z. D. Zhang, X. J. Mu, G. Ananda, B. Howie, K. J. Karczewski, K. S. Smith, V. Anaya, R. Richardson, J. Davis, Consortium 1000 Genome Project, B. Timmermann, D. G. MacArthur, A. Sidow, L. Duret, M. Gerstein, K. D. Makova, J. Marchini, G. McVean, and G. Lunter, "The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes," Genome Research 23 (5), 749-761 (2013).

Radmila Feldmann, Cornelius Fischer, Vitam Kodelja, Sarah Behrens, Stefan Haas, Martin Vingron, Bernd Timmermann, Anne Geikowski, and Sascha Sauer, "Genome-wide analysis of LXRalpha activation reveals new transcriptional networks in human atherosclerotic foam cells," Nucleic Acids Research (London) 41 (6), 3518-3531 (2013).

Radmila Feldmann, Cornelius Fischer, Vitam Kodelja, Sarah Behrens, Stefan Haas, Martin Vingron, Bernd Timmermann, Anne Geikowski, and Sascha Sauer, "Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells," Nucleic Acids Research (London) 41 (6), 3518-3531 (2013).

M. Weimann, A. Grossmann, J. Woodsmith, Z. Özkan, P. Birth, D. Meierhofer, N. Benlasfer, T. Valovka, B. Timmermann, E. E. Wanker, S. Sauer, and U. Stelzl, "A Y2H-seq approach defines the human protein methyltransferase interactome," Nature methods 10 (4), 339-342 (2013).

H. Bu, M. R. Schweiger, T. Manke, A. Wunderlich, B. Timmermann, M. Kerick, L. Pasqualini, E. Shehu, C. Fuchsberger, A. C. Cato, and H. Klocker, "Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells," FEBS Journal 280 (5), 1249-66 (2013).

Christina Grimm, Lukas Chavez, Mireia Vilardell, Alexandra Farrall, Sascha Tierling, Julia W. Böhm, Phillip Grote, Matthias Lienhard, Jörn Dietrich, Bernd Timmermann, Jörn Walter, Michal R. Schweiger, Hans Lehrach, Ralf Herwig, Bernhard G. Herrmann, and Markus Morkel, "DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer," PLoS Genetics 9 (2), e1003250-e1003250 (2013).

M. R. Schweiger, C. Barmeyer, and B. Timmermann, "Genomics and epigenomics: new promises of personalized medicine for cancer patients," Briefings in Functional Genomics 12 (5), 411-21 (2013).

Yali Xue, Yuan Chen, Qasim Ayub, Ni Huang, Edward V. Ball, Matthew Mort, Andrew D. Phillips, Katy Shaw, Peter D. Stenson, David N. Cooper, Chris Tyler-Smith, The 1000 Genomes Project Consortium, Bernd Timmermann, Hans Lehrach, and Ralf Herwig, "Deleterious- and Disease-Allele Prevalence in Healthy Individuals: Insights from Current Predictions, Mutation Databases, and Population-Scale Resequencing," The American Journal of Human Genetics 91 (6), 1022-1031 (2012).

Etmar Bulk, Jun Yu, Antje Hascher, Steffen Koschmieder, Rainer Wiewrodt, Utz Krug, Bernd Timmermann, Alessandro Marra, Ludger Hillejan, Karsten Wiebe, Wolfgang E. Berdel, Albrecht Schwab, and Carsten Müller-Tidow, "Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer," PLoS One 7 (12), e44591 (2012).

Seval Türkmen, Bernd Timmermann, Gesine Bartels, Daniela Gröger, Claus Meyer, Stefan Schwartz, Claudia Haferlach, Harald Rieder, Nicola Gökbuget, Dieter Hoelzer, Rolf Marschalek, and Thomas Burmeister, "Involvement of the MLL gene in adult T-lymphoblastic leukemia," Genes, Chromosomes and Cancer 51 (12), 1114-1124 (2012).

Goncalo R. Abecasis, Adam Auton, Lisa D. Brooks, Mark A. DePristo, Richard M. Durbin, Robert E. Handsaker, Hyun Min Kang, Gabor T. Marth, Gil A. McVean, The 1000 Genomes Project Consortium, Ralf Sudbrak, Marcus Albrecht, Vyacheslav Amstislavskiy, Tatiana A. Borodina, Alexey Davydov, Ralf Herwig, Matthias Lienhard, Florian Mertes, Marc Sultan, Bernd Timmermann, Marie L. Yaspo, and Hans Lehrach, "An integrated map of genetic variation from 1,092 human genomes," Nature 491 (7422), 56-65 (2012).

S. Börno, A. Fischer, M. Kerick, M. Falth, M. Laible, J. C. Brase, R. Kuner, A. Dahl, C. Grimm, B. Sayanjali, M. Isau, C. Röhr, A. Wunderlich, B. Timmermann, R. Claus, C. Plass, M. Graefen, R. Simon, F. Demichelis, M. A. Rubin, G. Sauter, T. Schlomm, H. Sültmann, H. Lehrach, and M. R. Schweiger, "Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation," Cancer Discovery 2 (11), 1024-1035 (2012).

M. Spielmann, F. Brancati, P. M. Krawitz, P. N. Robinson, D. M. Ibrahim, M. Franke, J. Hecht, S. Lohan, K. Dathe, A. M. Nardone, P. Ferrari, A. Landi, L. Wittler, B. Timmermann, D. Chan, U. Mennen, E. Klopocki, and S. Mundlos, "Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus," American Journal of Human Genetics 91 (4), 629-635 (2012).

Markus Ralser and Bernd Timmermann, "Genomanalyse von Modellorganismen: Saccharomyces cerevisiae," Biospektrum 18 (5), 504-507 (2012).

Markus Ralser, Heiner Kuhl, Meryem Ralser, Martin Werber, Hans Lehrach, Michael Breitenbach, and Bernd Timmermann, "The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt," Open Biology 2 (8), 120093 (2012).

The 1000 Genomes Project Consortium, Ralf Sudbrak, Marcus Albrecht, Vyacheslav Amstislavskiy, Tatiana A. Borodina, Andreas Dahl, Alexey Davydov, Ralf Herwig, Peter Marquardt, Florian Mertes, Wilfried Nietfeld, Dmitri Parkhomchuk, Aleksey Soldatov, Bernd Timmermann, Marius Tolzmann, and Hans Lehrach, "The 1000 Genomes Project: data management and community access," Nature methods 9 (5), 459-462 (2012).

D. G. MacArthur, S. Balasubramanian, A. Frankish, Consortium 1000 Genomes Project, R. Sudbrak, M. W. Albrecht , V. Amstislavskiy, T. A. Borodina, Andreas Dahl, A. Davydov, R. Herwig, P. Marquardt, F. Mertes, W. Nietfeld, D. Parkhomchuk, A. Soldatov, B. Timmermann, M. Tolzmann, and H. Lehrach, "A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes," Science 335 (6070), 823-828 (2012).

J. Goke, M. Jung, S. Behrens, L. Chavez, S. O'Keeffe, B. Timmermann, H. Lehrach, J. Adjaye, and M. Vingron, "Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development," PLoS Comput Biol 7 (12), e1002304 (2011).

M. Kerick, M. Isau, B. Timmermann, H. Sultmann, R. Herwig, S. Krobitsch, G. Schaefer, I. Verdorfer, G. Bartsch, H. Klocker, H. Lehrach, and M. R. Schweiger, "Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity," BMC Med Genomics 4, 68 (2011).