Publikationen von R. Herwig

M. Schütte, T. Risch, N. Abdavi Azar, K. Boehnke, D. Schumacher, M. Keil, R. Yildiriman, C. Jandrasits, T. Borodina, V. Amstislavskiy, C. L. Worth, C. Schweiger, S. Liebs, M. Lange, H. J. Warnatz, L. M. Butcher, J. E. Barrett, M. Sultan, C. Wierling, N. Golob-Schwarzl, S. Lax, S. Uranitsch, M. Becker, Y. Welte, J. L. Regan, M. Silvestrov, I. Kehler, A. Fusi, T. Kessler, R. Herwig, U. Landegren, D. Wienke, M. Nilsson, J. A. Velasco, P. Garin-Chesa, C. Reinhard, S. Beck, R. Schafer, C. R. Regenbrecht, D. Henderson, B. Lange, J. Haybaeck, U. Keilholz, J. Hoffmann, H. Lehrach, and M. L. Yaspo, "Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors," Nature Communications 8, 8:14262 (2017).

R. Herwig, C. Hardt, M. Lienhard, and A. Kamburov, "Analyzing and interpreting genome data at the network level with ConsensusPathDB," Nature Protocols 11 (10), 1889-1907 (2016).

R. Herwig, H. Gmuender, R. Corvi, K. M. Bloch, A. Brandenburg, J. Castell, L. Ceelen, C. Chesne, T. Y. Doktorova, D. Jennen, P. Jennings, A. Limonciel, E. A. Lock, T. McMorrow, P. Phrakonkham, R. Radford, C. Slattery, R. Stierum, M. Vilardell, T. Wittenberger, R. Yildirimman, M. Ryan, V. Rogiers, and J. Kleinjans, "Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective," Archives of Toxikology 90 (9), 2215-2229 (2016).

F. Broecker, C. Hardt, R. Herwig, B. Timmermann, M. Kerick, A. Wunderlich, M. R. Schweiger, L. Borsig, M. Heikenwalder, H. Lehrach, and K. Moelling, "Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line," The FEBS Journal 283 (9), 1669-1688 (2016).

C. Hardt, M. E. Beber, A. Rasche, A. Kamburov, D. G. Hebels, J. C. Kleinjans, and R. Herwig, "ToxDB: pathway-level interpretation of drug-treatment data," Database (Oxford) 2016, baw052 (2016).

Peter H. Sudmant, Tobias Rausch, Eugene J. Gardner, Robert E. Handsaker, Alexej Abyzov, John Huddleston, The 1000 Genomes Project Consortium, Bernd Timmermann, Ralf Herwig, and Hans Lehrach, "An integrated map of structural variation in 2,504 human genomes," Nature 526 (7571), 75-81 (2015).

The 1000 Genome Project Consortium, Hans Lehrach, Vyacheslav Amstislavskiy, Matthias Lienhard, Florian Mertes, Marc Sultan, Bernd Timmermann, Marie-Laure Yaspo, and Ralf Herwig, "A global reference for human genetic variation," Nature 526 (7571), 68-74 (2015).

Diana M. Hendrickx, Hugo J. W. L. Aerts, Florian Caiment, Dominic Clark, Timothy M. D. Ebbels, Chris T. Evelo, Hans Gmuender, Dennie G. A. J. Hebels, Ralf Herwig, Jürgen Hescheler, Danyel G. J. Jennen, Marlon J. A. Jetten, Stathis Kanterakis, Hector C. Keun, Vera Matser, John P. Overington, Ekaterina Pilicheva, Ugis Sarkans, Marcelo P. Segura-Lepe, Isaia Sotiriadou, Timo Wittenberger, Clemens Wittwehr, Antonella Zanzi, and Jos C. S. Kleinjans, "diXa: a data infrastructure for chemical safety assessment," Bioinformatics 31 (9), 1505-1507 (2015).

Ralf Herwig, "Computational modeling of drug response with applications to neuroscience," Dialogues in Clinical Neuroscience 16 (4), 465-477 (2014).

Ralf Herwig, "Computational modelling of drug response with applications to neuroscience," Dialogues in Clinical Neuroscience 16 (4), 465-477 (2014).

Gerald Reiner, Felix Dreher, Mario Drungowski, Doris Hoeltig, Natalie Bertsch, Martin Selke, Hermann Willems, Gerald Friedrich Gerlach, Inga Probst, Burkhardt Tuemmler, Karl-Heinz Waldmann, and Ralf Herwig, "Pathway deregulation and expression QTLs in response to Actinobacillus pleuropneumoniae infection in swine," Mammalian Genome 25 (11-12), 600-617 (2014).

Helen J. Hülsmann, Jana Rolff, Christian Bender, Mostafa Jarahian, Ulrike Korf, Ralf Herwig, Holger Fröhlich, Michael Thomas, Johannes Merk, Iduna Fichtner, Holger Sültmann, and Ruprecht Kuner, "Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib," Lung Cancer 86 (2), 151-157 (2014).

Thomas Willems, Melissa Gymrek, Gareth Highnam, Consortium The 1000 Genomes Project, Ralf Herwig, Hans Lehrach, Ralf Sudbrak, Bernd Timmermann, David Mittelman, and Yaniv Erlich, "The landscape of human STR variation," Genome Research 24 (11), 1894-1904 (2014).

Axel Rasche, Matthias Lienhard, Marie-Laure Yaspo, Hans Lehrach, and Ralf Herwig, "ARH-seq: identification of differential splicing in RNA-seq data," Nucleic Acids Research (London) 42 (14), e110 (2014).

V. Colonna, Q. Ayub, Y. Chen, L. Pagani, P. Luisi, M. Pybus, E. Garrison, Y. Xue, C. Tyler-Smith, Consortium 1000 Genomes Project, R. Sudbrak, M. Albrecht, V. Amstislavskiy, T. A. Borodina, A. Dahl, A. Davydov, R. Herwig, P. Marquardt, F. Mertes, W. Nietfeld, D. Parkhomchuk, A. V. Soldatov, B. Timmermann, M. Tolzmann, H. Lehrach, and M. L. Yaspo, "Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences," Genome Biology: Biology for the Post-Genomic Era 15 (6), R88 (2014).

O. Delaneau, J. Marchini, Consortium 1000 Genomes Project, H. Lehrach, R. Sudbrak, V. S. Amstislavskiy, M. Lienhard, F. Mertes, M. Sultan, B. Timmermann, M. L. Yaspo, and R. Herwig, "Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel," Nature Communications 5, 5:3934 (2014).

Tatyana Y. Doktorova, Reha Yildirimman, Liesbeth Ceelen, Mireia Vilardell, Tamara Vanhaecke, Mathieu Vinken, Gamze Ates, Anja Heymans, Hans Gmuender, Roque Bort, Raffaella Corvi, Pascal Phrakonkham, Ruoya Li, Nicolas Mouchet, Christophe Chesne, Joost van Delft, Jos Kleinjans, Jose Castell, Ralf Herwig, and Vera Rogiers, "Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model," Experimental and Clinical Sciences Journal (EXCLI Journal) 13, 623-637 (2014).

Gerald Reiner, Natalie Bertsch, Doris Hoeltig, Martin Selke, Hermann Willems, Gerald Friedrich Gerlach, Burkhard Tuemmler, Inga Probst, Ralf Herwig, Mario Drungowski, and Karl Heinz Waldmann, "Identification of QTL affecting resistance/susceptibility to acute Actinobacillus pleuropneumoniae infection in swine," Mammalian Genome 25 (3-4), 180-191 (2014).

Dennie G. A. Hebels, Marlon J. A. Jetten, Hugo J. W. Aerts, Ralf Herwig, Daniël H. J. Theunissen, Stan Gaj, Joost H. van Delft, and Jos C. S. Kleinjans, "Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity," Biomarkers in Medicine 8 (2), 185-200 (2014).

Matthias Lienhard, Christina Grimm, Markus Morkel, Ralf Herwig, and Lukas Chavez, "MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments," Bioinformatics 30 (2), 284-286 (2014).